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ALASPAN TABLET

ALASPAN TABLET

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Alaspan 10mg Tablet by Bayer Pharmaceuticals is a second-generation, non-sedating oral antihistamine formulated to provide targeted relief from histamine-mediated allergic reactions in companion animals. It addresses a broad spectrum of allergy presentations, including seasonal environmental allergies, allergic skin disease, insect bite and sting reactions, urticaria (hives), and mild to moderate allergic rhinitis, by selectively blocking the peripheral histamine H1 receptor without the marked central nervous system sedation associated with older, first-generation antihistamines. Used under veterinary guidance in dogs and, to a lesser extent, cats, Alaspan 10mg offers a low-sedation, once-daily antihistamine option that can form part of a broader allergy management protocol for your companion animal. Animeal is proud to offer Alaspan 10mg Tablet as part of its curated range of veterinary-applicable pharmaceutical solutions, supporting informed, compassionate allergy care for your canine or feline companion.

Ingredients:

Loratadine (Loratadinum), 10mg per tablet: Loratadine is a second-generation, long-acting tricyclic antihistamine of the piperidine class that exerts its therapeutic effect by competitively and selectively antagonising peripheral histamine H1 receptors. Unlike first-generation antihistamines such as diphenhydramine, loratadine has a low affinity for crossing the blood-brain barrier due to its lipophobic molecular structure and P-glycoprotein-mediated efflux at the blood-brain barrier, which significantly reduces central nervous system penetration and the sedation and anticholinergic effects associated with older agents. At the cellular level, loratadine binds to H1 receptors on mast cells, basophils, vascular endothelium, and sensory nerve endings, preventing histamine from initiating the downstream signalling cascade that produces vasodilation, increased capillary permeability, tissue oedema, pruritus, and smooth muscle contraction. By occupying the H1 receptor before or during histamine release, loratadine intercepts the early-phase allergic response and attenuates the severity of the inflammatory chain, reducing the clinical manifestations of allergic reactions including itching, erythema, urticaria, sneezing, and ocular and nasal discharge. Its extended plasma half-life, along with that of its active metabolite descarboethoxyloratadine, supports sustained H1 receptor occupancy across a once-daily dosing interval, making it particularly effective as a long-term preventive agent rather than purely an acute rescue medication.

Low-Sedation Allergy Relief for Everyday Comfort:
Unlike older antihistamines, Alaspan 10mg's selective peripheral H1 receptor blockade means your companion animal can experience meaningful allergy relief without the drowsiness, disorientation, and reduced alertness that characterise first-generation agents. This makes it a well-tolerated option for daily, ongoing use in pets with chronic or seasonal allergic conditions, supporting normal activity levels and quality of life throughout the treatment period.

Broad-Spectrum Histamine Control Across Allergy Types:
Alaspan 10mg targets the common histamine-driven pathway underlying a wide variety of allergic presentations, including environmental allergies triggered by pollen, dust mites, and mould spores, insect bite and sting reactions, urticaria, and food-related allergic skin responses. This versatility means your canine or feline companion can benefit from the same clinically trusted molecule across different allergy triggers, simplifying their allergy management under veterinary guidance.

Preventive Flare Reduction with Long-Acting Coverage:
Loratadine and its active metabolite descarboethoxyloratadine maintain sustained H1 receptor blockade across an extended dosing window, making Alaspan 10mg most effective when used consistently over time rather than as a single acute dose. Long-term daily use reinforces a preventive barrier against allergic flare-ups, progressively reducing the frequency and intensity of allergic episodes in pets with recurrent seasonal or environmental sensitivities.

Support for Mast Cell-Related Histamine Excess:
Preliminary evidence suggests that loratadine's capacity to block H1 receptors may also help manage histamine-mediated inflammatory symptoms in animals with mast cell tumours, where cancerous mast cells release elevated circulating levels of histamine. While this application requires direct veterinary oversight and is not a replacement for primary oncological management, Alaspan 10mg may serve as a valuable adjunctive component in your companion's multifaceted treatment plan under specialist guidance.

Antihistamine Trial Suitability Across Species:
Loratadine belongs to the piperidine class of antihistamines, a distinct pharmacological family from the ethanolamine and phenothiazine classes, meaning it offers a clinically differentiated option when antihistamines from other classes have not delivered adequate relief for your companion animal. Veterinary dermatologists frequently incorporate loratadine into sequential antihistamine trials for allergic skin disease in both dogs and cats, recognising its particular utility in feline patients where antihistamines in general demonstrate stronger efficacy relative to dogs.

How to Use:

Alaspan 10mg Tablet must be used only under the direction and prescription of a qualified veterinarian, who will determine the appropriate dose based on your companion animal's species, body weight, specific allergic condition, and response to therapy. The tablet should be administered orally and may be given with or without food; consistency in the timing of daily administration is recommended to maintain stable plasma concentrations and optimise the preventive effect of the medication. The tablet should be swallowed whole and not crushed, broken, or dissolved in liquid unless specifically instructed by your veterinarian. It is important to note that human loratadine combination formulations, particularly those containing pseudoephedrine (sold as Claritin-D and similar variants), must never be used in pets, as pseudoephedrine is toxic to companion animals; only plain loratadine formulations such as Alaspan 10mg are appropriate for veterinary use. Similarly, loratadine syrup formulations preserved in propylene glycol must not be administered to cats. Do not discontinue or adjust the dose without consulting your veterinarian, and inform them of all other medications your companion is currently receiving to avoid potential interactions with agents such as ketoconazole, erythromycin, or cimetidine, which may elevate plasma loratadine concentrations.

Storage Advice:

Store unopened Alaspan 10mg Tablet in a cool, dry place below 25 degrees C away from direct sunlight. Do not freeze. Once opened, keep the strip in its original blister packaging and reseal after each use to protect the remaining tablets from moisture and humidity. Keep out of reach of children and pets at all times. Do not use after the best-before date printed on the blister strip or carton.

About the Brand:

Founded globally on August 1, 1863, in Barmen, Germany, Bayer is one of the world's foremost life sciences companies, with a presence across 80 countries and a consistently recognised track record of quality, including receipt of the Great Place to Work certification for six consecutive years in India and designation among the Best Companies for Women in India. Bayer has been present in India since 1896, when it established its first wholly owned Asian subsidiary in Mumbai, and its Indian pharmaceutical operations today are driven by a strategic commitment to first-in-class, innovative therapies, underpinned by manufacturing facilities that hold international quality certifications including LEED accreditation for its Vapi production site. Bayer's guiding mission of "Science For A Better Life," anchored in rigorous R&D and a philosophy of expanding access to proven medicines, aligns with Animeal's commitment to offering trusted, science-backed solutions for your companion animal's health and wellbeing. Discover Bayer today.

Disclaimer:

Please note that while Alaspan 10mg Tablet is formulated from loratadine, a second-generation antihistamine, and may be used in dogs and cats under veterinary prescription as a complementary antihistamine therapy, it is not an approved veterinary pharmaceutical and its use in animals is considered off-label; it must therefore be administered only under the explicit guidance of a qualified veterinarian. Alaspan 10mg is a complementary therapeutic aid and is not a replacement for prescribed primary allergy therapy, veterinary allergy testing, or specialist dermatological management in animals with moderate to severe allergic skin disease. For pets with liver disease, dry eye (keratoconjunctivitis sicca), known hypersensitivity to loratadine or any excipient, concurrent use of interacting medications, or those who are pregnant or lactating, consult your veterinarian before introducing this product. Animeal supports your pet's health and happiness journey but does not replace the advice of a qualified veterinary professional.

Q: Is Alaspan 10mg Tablet suitable for all companion animals?
Alaspan 10mg Tablet containing loratadine is most commonly used in dogs and, to a lesser extent, cats, when prescribed by a veterinarian for the management of mild to moderate allergic conditions. It is not recommended for use in animals with known liver disease, dry eye conditions, or hypersensitivity to loratadine, and its safety in pregnant or lactating animals has not been established, making veterinary consultation essential before use. Suitability across specific breeds, age groups, and body weights must always be determined on an individual basis by your veterinarian.
Q: How often should Alaspan 10mg Tablet be administered to my companion animal?
Alaspan 10mg Tablet is typically considered for once-daily administration in dogs based on its pharmacokinetic profile, though the exact frequency, dose, and duration of treatment must be prescribed by your veterinarian in accordance with your companion animal's specific condition, body weight, and clinical response. Long-term, consistent daily use is generally more effective for preventing allergic flare-ups than intermittent or reactive dosing, and your veterinarian will advise on the appropriate treatment duration.
Q: How effective is Alaspan 10mg for managing allergies in pets?
Loratadine, the active ingredient in Alaspan 10mg, offers clinically meaningful relief for mild to moderate histamine-mediated allergic conditions in companion animals, and is particularly noted for its greater efficacy in cats relative to dogs. It is most effective as a long-term preventive agent that reduces the severity and frequency of allergic flare-ups, rather than as a rapid-acting rescue medication during acute episodes, and may form part of a broader, multimodal allergy management plan as recommended by your veterinarian. Its efficacy varies between individual animals, and some dogs may require alternative or additional therapies if adequate relief is not achieved with loratadine alone.
Q: What are the potential side effects of Alaspan 10mg Tablet in companion animals?
Alaspan 10mg is generally well tolerated in companion animals, with drowsiness being reported less frequently than with older first-generation antihistamines due to loratadine's limited central nervous system penetration. Potential side effects include mild sedation, gastrointestinal disturbances, dry mouth, and, in cases of overdose, tachycardia and headache-equivalent signs. If your companion animal displays unusual lethargy, agitation, vomiting, or loss of appetite following administration, contact your veterinarian promptly for assessment.
Q: What makes Alaspan 10mg different from older antihistamine tablets such as diphenhydramine or chlorpheniramine?
Alaspan 10mg contains loratadine, a second-generation antihistamine that selectively targets peripheral H1 receptors with minimal affinity for crossing the blood-brain barrier, a pharmacological distinction that sharply reduces the sedation, drowsiness, and anticholinergic effects such as dry mouth and urinary retention commonly associated with first-generation antihistamines. This makes Alaspan 10mg a considerably more comfortable and practical option for daily, long-term allergy management in companion animals, as it allows therapeutic H1 receptor blockade to be maintained consistently without the compromised alertness and activity levels that older agents can cause. Its once-daily dosing interval further simplifies administration and supports better owner compliance throughout an extended allergy management programme.
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ALLERGY RELIEF

ALASPAN TABLET

By PIRAMAL
₹ 146.25
You save ₹ 16.25 (10%)
MRP ₹ 162.50 (Incl. taxes)

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₹ 146.25
MRP ₹ 162.50  10% OFF
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Alaspan 10mg Tablet by Bayer Pharmaceuticals is a second-generation, non-sedating oral antihistamine formulated to provide targeted relief from histamine-mediated allergic reactions in companion animals. It addresses a broad spectrum of allergy presentations, including seasonal environmental allergies, allergic skin disease, insect bite and sting reactions, urticaria (hives), and mild to moderate allergic rhinitis, by selectively blocking the peripheral histamine H1 receptor without the marked central nervous system sedation associated with older, first-generation antihistamines. Used under veterinary guidance in dogs and, to a lesser extent, cats, Alaspan 10mg offers a low-sedation, once-daily antihistamine option that can form part of a broader allergy management protocol for your companion animal. Animeal is proud to offer Alaspan 10mg Tablet as part of its curated range of veterinary-applicable pharmaceutical solutions, supporting informed, compassionate allergy care for your canine or feline companion.

Ingredients:

Loratadine (Loratadinum), 10mg per tablet: Loratadine is a second-generation, long-acting tricyclic antihistamine of the piperidine class that exerts its therapeutic effect by competitively and selectively antagonising peripheral histamine H1 receptors. Unlike first-generation antihistamines such as diphenhydramine, loratadine has a low affinity for crossing the blood-brain barrier due to its lipophobic molecular structure and P-glycoprotein-mediated efflux at the blood-brain barrier, which significantly reduces central nervous system penetration and the sedation and anticholinergic effects associated with older agents. At the cellular level, loratadine binds to H1 receptors on mast cells, basophils, vascular endothelium, and sensory nerve endings, preventing histamine from initiating the downstream signalling cascade that produces vasodilation, increased capillary permeability, tissue oedema, pruritus, and smooth muscle contraction. By occupying the H1 receptor before or during histamine release, loratadine intercepts the early-phase allergic response and attenuates the severity of the inflammatory chain, reducing the clinical manifestations of allergic reactions including itching, erythema, urticaria, sneezing, and ocular and nasal discharge. Its extended plasma half-life, along with that of its active metabolite descarboethoxyloratadine, supports sustained H1 receptor occupancy across a once-daily dosing interval, making it particularly effective as a long-term preventive agent rather than purely an acute rescue medication.

Low-Sedation Allergy Relief for Everyday Comfort:
Unlike older antihistamines, Alaspan 10mg's selective peripheral H1 receptor blockade means your companion animal can experience meaningful allergy relief without the drowsiness, disorientation, and reduced alertness that characterise first-generation agents. This makes it a well-tolerated option for daily, ongoing use in pets with chronic or seasonal allergic conditions, supporting normal activity levels and quality of life throughout the treatment period.

Broad-Spectrum Histamine Control Across Allergy Types:
Alaspan 10mg targets the common histamine-driven pathway underlying a wide variety of allergic presentations, including environmental allergies triggered by pollen, dust mites, and mould spores, insect bite and sting reactions, urticaria, and food-related allergic skin responses. This versatility means your canine or feline companion can benefit from the same clinically trusted molecule across different allergy triggers, simplifying their allergy management under veterinary guidance.

Preventive Flare Reduction with Long-Acting Coverage:
Loratadine and its active metabolite descarboethoxyloratadine maintain sustained H1 receptor blockade across an extended dosing window, making Alaspan 10mg most effective when used consistently over time rather than as a single acute dose. Long-term daily use reinforces a preventive barrier against allergic flare-ups, progressively reducing the frequency and intensity of allergic episodes in pets with recurrent seasonal or environmental sensitivities.

Support for Mast Cell-Related Histamine Excess:
Preliminary evidence suggests that loratadine's capacity to block H1 receptors may also help manage histamine-mediated inflammatory symptoms in animals with mast cell tumours, where cancerous mast cells release elevated circulating levels of histamine. While this application requires direct veterinary oversight and is not a replacement for primary oncological management, Alaspan 10mg may serve as a valuable adjunctive component in your companion's multifaceted treatment plan under specialist guidance.

Antihistamine Trial Suitability Across Species:
Loratadine belongs to the piperidine class of antihistamines, a distinct pharmacological family from the ethanolamine and phenothiazine classes, meaning it offers a clinically differentiated option when antihistamines from other classes have not delivered adequate relief for your companion animal. Veterinary dermatologists frequently incorporate loratadine into sequential antihistamine trials for allergic skin disease in both dogs and cats, recognising its particular utility in feline patients where antihistamines in general demonstrate stronger efficacy relative to dogs.

How to Use:

Alaspan 10mg Tablet must be used only under the direction and prescription of a qualified veterinarian, who will determine the appropriate dose based on your companion animal's species, body weight, specific allergic condition, and response to therapy. The tablet should be administered orally and may be given with or without food; consistency in the timing of daily administration is recommended to maintain stable plasma concentrations and optimise the preventive effect of the medication. The tablet should be swallowed whole and not crushed, broken, or dissolved in liquid unless specifically instructed by your veterinarian. It is important to note that human loratadine combination formulations, particularly those containing pseudoephedrine (sold as Claritin-D and similar variants), must never be used in pets, as pseudoephedrine is toxic to companion animals; only plain loratadine formulations such as Alaspan 10mg are appropriate for veterinary use. Similarly, loratadine syrup formulations preserved in propylene glycol must not be administered to cats. Do not discontinue or adjust the dose without consulting your veterinarian, and inform them of all other medications your companion is currently receiving to avoid potential interactions with agents such as ketoconazole, erythromycin, or cimetidine, which may elevate plasma loratadine concentrations.

Storage Advice:

Store unopened Alaspan 10mg Tablet in a cool, dry place below 25 degrees C away from direct sunlight. Do not freeze. Once opened, keep the strip in its original blister packaging and reseal after each use to protect the remaining tablets from moisture and humidity. Keep out of reach of children and pets at all times. Do not use after the best-before date printed on the blister strip or carton.

About the Brand:

Founded globally on August 1, 1863, in Barmen, Germany, Bayer is one of the world's foremost life sciences companies, with a presence across 80 countries and a consistently recognised track record of quality, including receipt of the Great Place to Work certification for six consecutive years in India and designation among the Best Companies for Women in India. Bayer has been present in India since 1896, when it established its first wholly owned Asian subsidiary in Mumbai, and its Indian pharmaceutical operations today are driven by a strategic commitment to first-in-class, innovative therapies, underpinned by manufacturing facilities that hold international quality certifications including LEED accreditation for its Vapi production site. Bayer's guiding mission of "Science For A Better Life," anchored in rigorous R&D and a philosophy of expanding access to proven medicines, aligns with Animeal's commitment to offering trusted, science-backed solutions for your companion animal's health and wellbeing. Discover Bayer today.

Disclaimer:

Please note that while Alaspan 10mg Tablet is formulated from loratadine, a second-generation antihistamine, and may be used in dogs and cats under veterinary prescription as a complementary antihistamine therapy, it is not an approved veterinary pharmaceutical and its use in animals is considered off-label; it must therefore be administered only under the explicit guidance of a qualified veterinarian. Alaspan 10mg is a complementary therapeutic aid and is not a replacement for prescribed primary allergy therapy, veterinary allergy testing, or specialist dermatological management in animals with moderate to severe allergic skin disease. For pets with liver disease, dry eye (keratoconjunctivitis sicca), known hypersensitivity to loratadine or any excipient, concurrent use of interacting medications, or those who are pregnant or lactating, consult your veterinarian before introducing this product. Animeal supports your pet's health and happiness journey but does not replace the advice of a qualified veterinary professional.

Q: Is Alaspan 10mg Tablet suitable for all companion animals?
Alaspan 10mg Tablet containing loratadine is most commonly used in dogs and, to a lesser extent, cats, when prescribed by a veterinarian for the management of mild to moderate allergic conditions. It is not recommended for use in animals with known liver disease, dry eye conditions, or hypersensitivity to loratadine, and its safety in pregnant or lactating animals has not been established, making veterinary consultation essential before use. Suitability across specific breeds, age groups, and body weights must always be determined on an individual basis by your veterinarian.
Q: How often should Alaspan 10mg Tablet be administered to my companion animal?
Alaspan 10mg Tablet is typically considered for once-daily administration in dogs based on its pharmacokinetic profile, though the exact frequency, dose, and duration of treatment must be prescribed by your veterinarian in accordance with your companion animal's specific condition, body weight, and clinical response. Long-term, consistent daily use is generally more effective for preventing allergic flare-ups than intermittent or reactive dosing, and your veterinarian will advise on the appropriate treatment duration.
Q: How effective is Alaspan 10mg for managing allergies in pets?
Loratadine, the active ingredient in Alaspan 10mg, offers clinically meaningful relief for mild to moderate histamine-mediated allergic conditions in companion animals, and is particularly noted for its greater efficacy in cats relative to dogs. It is most effective as a long-term preventive agent that reduces the severity and frequency of allergic flare-ups, rather than as a rapid-acting rescue medication during acute episodes, and may form part of a broader, multimodal allergy management plan as recommended by your veterinarian. Its efficacy varies between individual animals, and some dogs may require alternative or additional therapies if adequate relief is not achieved with loratadine alone.
Q: What are the potential side effects of Alaspan 10mg Tablet in companion animals?
Alaspan 10mg is generally well tolerated in companion animals, with drowsiness being reported less frequently than with older first-generation antihistamines due to loratadine's limited central nervous system penetration. Potential side effects include mild sedation, gastrointestinal disturbances, dry mouth, and, in cases of overdose, tachycardia and headache-equivalent signs. If your companion animal displays unusual lethargy, agitation, vomiting, or loss of appetite following administration, contact your veterinarian promptly for assessment.
Q: What makes Alaspan 10mg different from older antihistamine tablets such as diphenhydramine or chlorpheniramine?
Alaspan 10mg contains loratadine, a second-generation antihistamine that selectively targets peripheral H1 receptors with minimal affinity for crossing the blood-brain barrier, a pharmacological distinction that sharply reduces the sedation, drowsiness, and anticholinergic effects such as dry mouth and urinary retention commonly associated with first-generation antihistamines. This makes Alaspan 10mg a considerably more comfortable and practical option for daily, long-term allergy management in companion animals, as it allows therapeutic H1 receptor blockade to be maintained consistently without the compromised alertness and activity levels that older agents can cause. Its once-daily dosing interval further simplifies administration and supports better owner compliance throughout an extended allergy management programme.
ALASPAN TABLET
₹ 146.25
₹ 162.50  10% OFF

Frequently Asked Questions

Is Alaspan 10mg Tablet suitable for all companion animals?

Alaspan 10mg Tablet containing loratadine is most commonly used in dogs and, to a lesser extent, cats, when prescribed by a veterinarian for the management of mild to moderate allergic conditions. It is not recommended for use in animals with known liver disease, dry eye conditions, or hypersensitivity to loratadine, and its safety in pregnant or lactating animals has not been established, making veterinary consultation essential before use. Suitability across specific breeds, age groups, and body weights must always be determined on an individual basis by your veterinarian.

How often should Alaspan 10mg Tablet be administered to my companion animal?

Alaspan 10mg Tablet is typically considered for once-daily administration in dogs based on its pharmacokinetic profile, though the exact frequency, dose, and duration of treatment must be prescribed by your veterinarian in accordance with your companion animal's specific condition, body weight, and clinical response. Long-term, consistent daily use is generally more effective for preventing allergic flare-ups than intermittent or reactive dosing, and your veterinarian will advise on the appropriate treatment duration.

How effective is Alaspan 10mg for managing allergies in pets?

Loratadine, the active ingredient in Alaspan 10mg, offers clinically meaningful relief for mild to moderate histamine-mediated allergic conditions in companion animals, and is particularly noted for its greater efficacy in cats relative to dogs. It is most effective as a long-term preventive agent that reduces the severity and frequency of allergic flare-ups, rather than as a rapid-acting rescue medication during acute episodes, and may form part of a broader, multimodal allergy management plan as recommended by your veterinarian. Its efficacy varies between individual animals, and some dogs may require alternative or additional therapies if adequate relief is not achieved with loratadine alone.

What are the potential side effects of Alaspan 10mg Tablet in companion animals?

Alaspan 10mg is generally well tolerated in companion animals, with drowsiness being reported less frequently than with older first-generation antihistamines due to loratadine's limited central nervous system penetration. Potential side effects include mild sedation, gastrointestinal disturbances, dry mouth, and, in cases of overdose, tachycardia and headache-equivalent signs. If your companion animal displays unusual lethargy, agitation, vomiting, or loss of appetite following administration, contact your veterinarian promptly for assessment.

What makes Alaspan 10mg different from older antihistamine tablets such as diphenhydramine or chlorpheniramine?

Alaspan 10mg contains loratadine, a second-generation antihistamine that selectively targets peripheral H1 receptors with minimal affinity for crossing the blood-brain barrier, a pharmacological distinction that sharply reduces the sedation, drowsiness, and anticholinergic effects such as dry mouth and urinary retention commonly associated with first-generation antihistamines. This makes Alaspan 10mg a considerably more comfortable and practical option for daily, long-term allergy management in companion animals, as it allows therapeutic H1 receptor blockade to be maintained consistently without the compromised alertness and activity levels that older agents can cause. Its once-daily dosing interval further simplifies administration and supports better owner compliance throughout an extended allergy management programme.
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