Bio-pet Glucochond Tablet (S)
In Stock
Bio PetActive GlucoCHOND by Bio PetActive is a scientifically formulated, multi-ingredient chewable joint supplement designed to address one of the most common and quality-of-life-limiting challenges facing dogs and cats of all ages: progressive joint degeneration, cartilage breakdown, and the pain and restricted mobility that accompany hip dysplasia, elbow dysplasia, osteoarthritis, and other musculoskeletal disorders. Unlike single-ingredient joint supplements, GlucoCHOND delivers a synergistic five-component formula Glucosamine, Chondroitin Sulphate, MSM, Manganese, and Vitamin C each chosen for its specific, evidence-supported role in cartilage repair, synovial fluid maintenance, and connective tissue protection. Presented as palatable chewable tablets that can be offered directly or crumbled into food, GlucoCHOND is as easy to administer as it is effective making consistent, daily joint support practical for every pet parent. Animeal is proud to offer Bio PetActive GlucoCHOND as part of its curated selection of internationally certified, premium-quality nutritional supplements for the long-term health and mobility of your canine and feline companions across India.
Ingredients:
Glucosamine 500 mg per tablet: Glucosamine (2-amino-2-deoxy-D-glucose) is an endogenously produced aminomonosaccharide that serves as the primary biosynthetic precursor for glycosaminoglycans the long-chain polysaccharide molecules that form the structural backbone of articular cartilage, synovial fluid, and joint-associated connective tissue. In ageing, injured, or dysplastic joints, the rate of cartilage catabolism exceeds the body's capacity for glucosamine biosynthesis and glycosaminoglycan replenishment, resulting in progressive thinning of the cartilage matrix, loss of joint cushioning, and bone-on-bone friction. Exogenous glucosamine supplementation at 500 mg per tablet provides the critical substrate required by chondrocytes (cartilage cells) to synthesise new proteoglycan and collagen molecules, effectively restoring the raw materials of cartilage regeneration. Glucosamine also exerts modest anti-inflammatory activity by modulating signalling pathways that drive chondrocyte-mediated cartilage destruction, making it both reparative and protective in its joint action.
Chondroitin Sulphate 250 mg per tablet: Chondroitin sulphate is a sulphated glycosaminoglycan a large, negatively charged polysaccharide that forms a core structural component of the extracellular matrix of articular cartilage, tendons, ligaments, corneal tissue, and mucous membranes throughout the body. Its high negative charge density attracts and retains water molecules within the cartilage matrix, maintaining the hydration and viscoelastic "shock-absorbing" properties of the tissue under compressive load. At the cellular level, chondroitin sulphate inhibits the activity of matrix-degrading enzymes (particularly matrix metalloproteinases and aggrecanases) that are upregulated in arthritic and degenerating joints, thereby slowing the enzymatic breakdown of the existing cartilage matrix while simultaneously stimulating chondrocyte anabolic activity. Clinical research consistently demonstrates that glucosamine and chondroitin sulphate act synergistically with chondroitin protecting the existing cartilage structure while glucosamine drives new matrix synthesis, producing a combined effect superior to either ingredient in isolation.
MSM (Methylsulfonylmethane) 200 mg per tablet: Methylsulfonylmethane (dimethyl sulfone, (CH₃)₂SO₂) is a naturally occurring, bioavailable organic sulphur compound found in small quantities in many fresh foods. Sulphur is an essential mineral for the cross-linking and stabilisation of collagen and keratin proteins the structural proteins of cartilage, tendons, ligaments, and joint capsule tissue. MSM supplementation provides a concentrated, readily absorbed source of biological sulphur, directly supporting the structural integrity of the cartilage matrix. Beyond its structural role, MSM exerts meaningful anti-inflammatory and antioxidant activity: it inhibits the nuclear factor-κB (NF-κB) inflammatory signalling pathway, reducing the production of pro-inflammatory cytokines (TNF-α, IL-1β, IL-6) that drive joint inflammation and pain in osteoarthritis. MSM also reduces oxidative stress within the joint microenvironment by supporting glutathione synthesis, protecting chondrocytes and synovial cells from reactive oxygen species-mediated damage particularly relevant in chronically inflamed joints where oxidative burden is elevated.
Manganese 15.94 mg per tablet: Manganese (Mn) is an essential trace mineral that functions as a critical cofactor for several key enzymes involved in cartilage and bone metabolism. Most critically, manganese is required for the activity of manganese superoxide dismutase (MnSOD) the primary mitochondrial antioxidant enzyme and for the enzyme glycosyltransferase, which is directly responsible for the biosynthesis of glycosaminoglycan chains within chondrocytes. Without adequate manganese, the assembly of chondroitin sulphate and hyaluronic acid proteoglycans is impaired at the enzymatic level, regardless of how much glucosamine or chondroitin sulphate is supplemented. Manganese therefore acts as an essential enabler of the joint-rebuilding activity of the other ingredients in GlucoCHOND, ensuring that the biosynthetic machinery within cartilage cells functions at full capacity. It also supports bone mineralisation and plays a role in the collagen cross-linking process that gives tendons and ligaments their tensile strength.
Vitamin C (Ascorbic Acid) 50 mg per tablet: Vitamin C (L-ascorbic acid) is an essential water-soluble micronutrient and one of the most important cofactors in collagen biosynthesis. At the molecular level, Vitamin C is required for the hydroxylation of proline and lysine residues in procollagen chains a step catalysed by the enzymes prolyl hydroxylase and lysyl hydroxylase that is essential for the formation of stable collagen triple-helix structures. Without adequate Vitamin C, collagen molecules cannot form stable cross-links, resulting in mechanically weak connective tissue, impaired cartilage repair capacity, and fragile ligaments and tendons. In addition to its collagen-supporting role, Vitamin C is a potent antioxidant in the aqueous phase of cells and synovial fluid, neutralising free radicals that contribute to chondrocyte apoptosis and inflammatory amplification in arthritic joints. The inclusion of Vitamin C in GlucoCHOND ensures that the collagen biosynthesis pathway is fully supported alongside cartilage matrix restoration making the entire formula more effective at the tissue level.
