Novartis Calborol Injection for Cattle, 450ml

Rapid IV Calcium Replenishment Acts Within Minutes: Intravenous Calborol delivers elemental calcium directly into the bloodstream, bypassing the digestive system entirely. Blood calcium levels begin rising within minutes of the start of slow IV infusion providing critically fast restoration of nerve transmission, muscle function, and cardiac rhythm in animals presenting with acute hypocalcaemia and collapse.

Gold Standard Milk Fever Treatment: Milk fever (parturient paresis) is the most common periparturient metabolic emergency in dairy cattle, with an annual incidence of 5 to 8% in dairy herds. It occurs when the sudden demand for calcium in colostrum and milk production at calving outpaces the cow's ability to mobilise calcium from bone and absorb it from feed causing rapid, dangerous hypocalcaemia. A typical treatment to an adult lactating dairy cow with periparturient hypocalcaemia is 500ml of 23% calcium borogluconate by slow intravenous injection with cardiac auscultation this provides 10.7g of calcium.Calborol's 450ml bottle is specifically sized for a full therapeutic dose in a standard dairy cow.

Nil Milk & Meat Withdrawal Safe for Dairy Animals: Calborol carries a zero-day withdrawal period for both milk and meat meaning treated dairy cows can return to milk production immediately after recovery, with no discarding of milk required and no delay in slaughter eligibility. This is a critical commercial and welfare advantage for dairy farmers.

Broad Multi-Species Application: Calborol is clinically indicated across a wide range of animal species including dairy cattle, beef cattle, buffaloes, sheep, goats, pigs, horses, dogs, and cats making it a versatile, essential addition to any veterinary clinic, dairy farm, or livestock operation's emergency medicine kit.

Treats the Full Spectrum of Hypocalcaemic Conditions: Beyond milk fever, Calborol is indicated for all conditions where rapidly raising blood calcium is clinically necessary including eclampsia (puerperal tetany) in whelping and lactating dogs and cats, hypoparathyroidism, grass tetany, transport tetany, hypocalcaemia secondary to renal failure, post-surgical hypocalcaemia, and rickets and osteomalacia in growing animals.

Superior Safety Profile Over Calcium Chloride: Calcium gluconate and calcium borogluconate are the preferred forms for intravenous and subcutaneous administration because CaCl2 causes extensive necrosis and sloughs of tissue when administered perivascularly. Calborol's Borogluconate formulation is safe for both IV and SC use a significant clinical safety advantage, especially in farm settings where perivascular injection can occur.

Improved Solubility & Shelf Life: Compared to calcium gluconate, calcium borogluconate has improved solubility and shelf life ensuring the solution remains clear, stable, and fully bioavailable throughout the product's entire shelf life, even in variable storage conditions encountered in farm and field settings.

Subcutaneous Administration Option for Field Use: When intravenous access is not immediately practical or in cases of moderate rather than severe hypocalcaemia, Calborol can be administered subcutaneously divided over multiple sites to facilitate absorption. This makes it practical for use in field conditions by trained farm staff under veterinary guidance.

Prevents Dangerous Secondary Complications of Milk Fever: Untreated or inadequately treated milk fever rapidly progresses from muscle weakness to recumbency to coma and death and also predisposes cows to a cascade of secondary conditions including mastitis, retained placenta, metritis, displaced abomasum, and ketosis. Prompt Calborol treatment halts this cascade, protecting both the animal's life and the farmer's productivity investment.

Supports Post-Whelping Recovery in Dogs & Cats: Calcium borogluconate is especially useful for dogs with eclampsia after whelping it can help in the treatment of hypocalcaemia and should be cautiously administered in dogs with heart problems. Eclampsia (milk fever in bitches and queens) is a serious and rapidly life-threatening condition in small animals Calborol under slow IV administration by a veterinarian is the emergency treatment of choice.

How to Use:

Calborol Injection is a prescription-only veterinary injectable and must be administered strictly under the supervision and guidance of a licensed veterinarian. Incorrect administration rate is the primary risk factor associated with this product always administer slowly with cardiac monitoring.

Important Care & Administration Notes:

• Before treatment, ensure the liquid is at the same temperature as the body temperature of the afflicted animal. Cold solution administered intravenously can cause cardiac arrhythmia warm the bottle to body temperature (approximately 38–39°C) before administration.
• Administer IV at a rate no faster than 1ml per kg body weight per minute continuous cardiac auscultation with a stethoscope during infusion is mandatory.
• If no improvement is noticed in the condition being treated after 24 hours, the diagnosis should be re-evaluated and a veterinarian consulted.
• In cases of severe hypocalcaemia, a second dose may be necessary always allow at least 6 to 12 hours between repeat doses and reassess the animal's condition before redosing.
• Do not retain a partially used vial discard any unused portion immediately after use to prevent microbial contamination of the remaining solution.
• Do not use in animals with known hypercalcaemia or digitalis toxicity.
• Use with extreme caution in animals with concurrent cardiac disease or renal failure consult a veterinarian before administration.

Storage Advice:
Store at room temperature between 15°C and 30°C in a cool, dry place away from direct sunlight and freezing temperatures. Do not refrigerate. Keep the bottle sealed until immediately before use. Keep out of reach of children. Do not use after the expiry date printed on the label.

About the Brand:

Calborol is a trusted, long-established veterinary injectable product distributed through leading veterinary pharmaceutical channels in India, manufactured to meet the strict quality and sterility standards required for parenteral veterinary medicines. The Calcium Borogluconate 23% formulation has been the internationally accepted gold standard for milk fever treatment since its first clinical use was reported in 1934 and remains, nearly a century later, the most widely prescribed and clinically trusted parenteral calcium therapy in veterinary medicine worldwide. At Animeal, we are proud to stock Calborol as part of our commitment to providing every veterinary professional, dairy farmer, and livestock health caretaker with access to reliable, pharmaceutical-grade emergency metabolic care products that protect the lives and productivity of animals across India.

Disclaimer:

Calborol Calcium Borogluconate Injection 23% is a prescription-only veterinary injectable medicine intended for use under the direct supervision of a licensed veterinarian only. Self-administration by untrained personnel carries serious risks of cardiovascular complications including fatal heart block if administered too rapidly. This product is strictly for animal use only it is not intended for human use. Animeal provides product information as a reference only this does not substitute a veterinary diagnosis, clinical examination, or individually prescribed treatment protocol. Contraindicated in animals with hypercalcaemia, severe renal failure, or digitalis toxicity. Use with extreme caution in animals with known cardiac disease. Discard partially used vials immediately after use. Keep out of reach of children.