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CONCIPLEX INJ (L)
CONCIPLEX INJ (L)
By CONCEPT
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Conciplex Vitamin B Complex Injection by Concept Pharmaceuticals Ltd. is a cutting-edge, high-potency parenteral B-vitamin formulation specifically developed to address the acute and chronic consequences of B-complex deficiency in cattle, sheep, dogs, and other livestock and companion animals. B-group vitamins are water-soluble and cannot be stored in meaningful quantities within the body, making them uniquely vulnerable to rapid depletion during periods of illness, fever, physiological stress, poor appetite, parasitic burden, post-surgical recovery, and intensive antibiotic therapy. When oral intake is compromised or absorption is inadequate, parenteral supplementation bypasses the gastrointestinal route entirely, delivering all six essential B-vitamins directly into systemic circulation at therapeutic concentrations, where they are immediately available to tissues, nerves, and metabolic pathways that depend upon them. Conciplex is formulated as an isotonic solution, making it exceptionally well-tolerated at the injection site and suitable for co-administration alongside antibacterial therapy. Animeal is proud to offer Conciplex Vitamin B Complex Injection 100ml as a reliable, veterinarian-trusted nutritional intervention for animals in need of rapid metabolic and neurological support.
Ingredients:
Thiamine (Vitamin B1) 33.3 mg/ml: Thiamine (3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium) functions as the essential coenzyme thiamine pyrophosphate (TPP) in carbohydrate metabolism, specifically as a cofactor for pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, and transketolase. These enzyme complexes are central to aerobic glucose oxidation and the pentose phosphate pathway. Deficiency of Thiamine in animals, particularly ruminants, leads to a condition known as polioencephalomalacia (cerebrocortical necrosis), characterised by neurological degeneration, muscular tremors, blindness, and eventual recumbency. At the high concentration present in Conciplex, parenteral Thiamine rapidly restores coenzyme availability within neural and muscular tissues, supporting recovery from nerve weakness, incoordination, and metabolic depression.
Riboflavin (Vitamin B2) 1.66 mg/ml: Riboflavin (7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4-dione) is the precursor to flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), two critical coenzymes embedded in the electron transport chain and responsible for cellular energy generation via oxidative phosphorylation. FAD-dependent enzymes such as succinate dehydrogenase and glutathione reductase play pivotal roles in cellular antioxidant defence and macronutrient catabolism. Riboflavin deficiency in animals presents as poor growth, dermatitis, oral mucosal lesions, and impaired corneal health, making its parenteral restoration important in debilitated or anorexic patients.
Pyridoxine (Vitamin B6) 3.3 mg/ml: Pyridoxine hydrochloride (5-hydroxy-6-methylpyridine-3,4-dimethanol hydrochloride) is metabolically activated to pyridoxal-5-phosphate (PLP), the active coenzyme form that participates in over 100 enzymatic reactions, including transamination, decarboxylation, and racemisation of amino acids. PLP is essential for the biosynthesis of neurotransmitters including serotonin, dopamine, and gamma-aminobutyric acid (GABA), as well as for haemoglobin synthesis via the porphyrin pathway. In states of B6 deficiency, animals exhibit microcytic anaemia, peripheral neuropathy, and immunosuppression, all of which are directly addressed by parenteral replenishment.
Nicotinamide (Vitamin B3) 33.3 mg/ml: Nicotinamide (pyridine-3-carboxamide) is the amide form of niacin and the direct precursor to nicotinamide adenine dinucleotide (NAD+) and its phosphate form (NADP+), which serve as universal electron carriers across hundreds of metabolic oxidation-reduction reactions. NAD+ is critical to glycolysis, the tricarboxylic acid cycle, and fatty acid beta-oxidation, while NADP+ drives biosynthetic pathways and the regeneration of reduced glutathione as a primary antioxidant. Nicotinamide also reinforces mucosal and dermal barrier integrity, making its inclusion in Conciplex particularly relevant for animals presenting with oral ulceration, lip sores, and skin deterioration.
D-Panthenol (Provitamin B5) 1.66 mg/ml: D-Panthenol (D-(+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide) is the alcohol precursor to pantothenic acid (Vitamin B5), which is converted within tissues to coenzyme A (CoA). CoA is an indispensable acyl-group carrier involved in the synthesis and oxidation of fatty acids, the activation of acetate for entry into the TCA cycle, and the biosynthesis of steroid hormones, haemoglobin, and acetylcholine. D-Panthenol is selected over pantothenic acid itself for parenteral formulations due to its superior chemical stability in aqueous solution, ensuring preserved potency throughout the product's shelf life.
Cyanocobalamin (Vitamin B12) 33.3 mcg/ml: Cyanocobalamin (cobalt-containing corrinoid coenzyme) is the most bioavailable pharmaceutical form of Vitamin B12, which serves as a cofactor for two critical enzymes in the body: methylmalonyl-CoA mutase and methionine synthase. Methylmalonyl-CoA mutase catalyses the conversion of methylmalonyl-CoA to succinyl-CoA within the TCA cycle, directly linking odd-chain fatty acid and amino acid catabolism to energy production. Methionine synthase is required for the remethylation of homocysteine to methionine, a reaction essential for DNA synthesis, myelin formation, and one-carbon metabolism. In animals, Vitamin B12 deficiency causes megaloblastic anaemia, peripheral neuropathy, reproductive failure, and poor weight gain, all of which are targeted by the high-concentration Cyanocobalamin in this formulation.
CONCIPLEX INJ (L)
In Stock
Conciplex Vitamin B Complex Injection by Concept Pharmaceuticals Ltd. is a cutting-edge, high-potency parenteral B-vitamin formulation specifically developed to address the acute and chronic consequences of B-complex deficiency in cattle, sheep, dogs, and other livestock and companion animals. B-group vitamins are water-soluble and cannot be stored in meaningful quantities within the body, making them uniquely vulnerable to rapid depletion during periods of illness, fever, physiological stress, poor appetite, parasitic burden, post-surgical recovery, and intensive antibiotic therapy. When oral intake is compromised or absorption is inadequate, parenteral supplementation bypasses the gastrointestinal route entirely, delivering all six essential B-vitamins directly into systemic circulation at therapeutic concentrations, where they are immediately available to tissues, nerves, and metabolic pathways that depend upon them. Conciplex is formulated as an isotonic solution, making it exceptionally well-tolerated at the injection site and suitable for co-administration alongside antibacterial therapy. Animeal is proud to offer Conciplex Vitamin B Complex Injection 100ml as a reliable, veterinarian-trusted nutritional intervention for animals in need of rapid metabolic and neurological support.
Ingredients:
Thiamine (Vitamin B1) 33.3 mg/ml: Thiamine (3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium) functions as the essential coenzyme thiamine pyrophosphate (TPP) in carbohydrate metabolism, specifically as a cofactor for pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, and transketolase. These enzyme complexes are central to aerobic glucose oxidation and the pentose phosphate pathway. Deficiency of Thiamine in animals, particularly ruminants, leads to a condition known as polioencephalomalacia (cerebrocortical necrosis), characterised by neurological degeneration, muscular tremors, blindness, and eventual recumbency. At the high concentration present in Conciplex, parenteral Thiamine rapidly restores coenzyme availability within neural and muscular tissues, supporting recovery from nerve weakness, incoordination, and metabolic depression.
Riboflavin (Vitamin B2) 1.66 mg/ml: Riboflavin (7,8-dimethyl-10-[(2S,3S,4R)-2,3,4,5-tetrahydroxypentyl]benzo[g]pteridine-2,4-dione) is the precursor to flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), two critical coenzymes embedded in the electron transport chain and responsible for cellular energy generation via oxidative phosphorylation. FAD-dependent enzymes such as succinate dehydrogenase and glutathione reductase play pivotal roles in cellular antioxidant defence and macronutrient catabolism. Riboflavin deficiency in animals presents as poor growth, dermatitis, oral mucosal lesions, and impaired corneal health, making its parenteral restoration important in debilitated or anorexic patients.
Pyridoxine (Vitamin B6) 3.3 mg/ml: Pyridoxine hydrochloride (5-hydroxy-6-methylpyridine-3,4-dimethanol hydrochloride) is metabolically activated to pyridoxal-5-phosphate (PLP), the active coenzyme form that participates in over 100 enzymatic reactions, including transamination, decarboxylation, and racemisation of amino acids. PLP is essential for the biosynthesis of neurotransmitters including serotonin, dopamine, and gamma-aminobutyric acid (GABA), as well as for haemoglobin synthesis via the porphyrin pathway. In states of B6 deficiency, animals exhibit microcytic anaemia, peripheral neuropathy, and immunosuppression, all of which are directly addressed by parenteral replenishment.
Nicotinamide (Vitamin B3) 33.3 mg/ml: Nicotinamide (pyridine-3-carboxamide) is the amide form of niacin and the direct precursor to nicotinamide adenine dinucleotide (NAD+) and its phosphate form (NADP+), which serve as universal electron carriers across hundreds of metabolic oxidation-reduction reactions. NAD+ is critical to glycolysis, the tricarboxylic acid cycle, and fatty acid beta-oxidation, while NADP+ drives biosynthetic pathways and the regeneration of reduced glutathione as a primary antioxidant. Nicotinamide also reinforces mucosal and dermal barrier integrity, making its inclusion in Conciplex particularly relevant for animals presenting with oral ulceration, lip sores, and skin deterioration.
D-Panthenol (Provitamin B5) 1.66 mg/ml: D-Panthenol (D-(+)-2,4-dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutanamide) is the alcohol precursor to pantothenic acid (Vitamin B5), which is converted within tissues to coenzyme A (CoA). CoA is an indispensable acyl-group carrier involved in the synthesis and oxidation of fatty acids, the activation of acetate for entry into the TCA cycle, and the biosynthesis of steroid hormones, haemoglobin, and acetylcholine. D-Panthenol is selected over pantothenic acid itself for parenteral formulations due to its superior chemical stability in aqueous solution, ensuring preserved potency throughout the product's shelf life.
Cyanocobalamin (Vitamin B12) 33.3 mcg/ml: Cyanocobalamin (cobalt-containing corrinoid coenzyme) is the most bioavailable pharmaceutical form of Vitamin B12, which serves as a cofactor for two critical enzymes in the body: methylmalonyl-CoA mutase and methionine synthase. Methylmalonyl-CoA mutase catalyses the conversion of methylmalonyl-CoA to succinyl-CoA within the TCA cycle, directly linking odd-chain fatty acid and amino acid catabolism to energy production. Methionine synthase is required for the remethylation of homocysteine to methionine, a reaction essential for DNA synthesis, myelin formation, and one-carbon metabolism. In animals, Vitamin B12 deficiency causes megaloblastic anaemia, peripheral neuropathy, reproductive failure, and poor weight gain, all of which are targeted by the high-concentration Cyanocobalamin in this formulation.
