CRESP 40MG INJ [0.4ML]

Stimulates Red Blood Cell Production: Cresp 40mcg Injection contains the protein Darbepoetin alfa, which works by providing signals to the bone marrow to make more red blood cells directly addressing the root cause of anaemia by restoring the body's ability to produce sufficient red blood cells and haemoglobin.

Treats Anaemia in Chronic Kidney Disease (CKD): In chronic kidney disease, when the kidney fails to produce sufficient erythropoietin protein which aids in the formation of red blood cells, Cresp 40mcg Injection stimulates the production of this protein in the bone marrow restoring red blood cell levels and relieving debilitating anaemia symptoms in CKD patients on and off dialysis.

Treats Chemotherapy-Induced Anaemia: Cresp 40mcg Injection helps cancer patients maintain adequate haemoglobin levels during chemotherapy treatment reducing the need for blood transfusions and improving the patient's energy levels and quality of life throughout the course of cancer treatment.

Extended Half-Life Less Frequent Dosing: Increased glycosylation is responsible for the increased half-life of Darbepoetin alfa. Subcutaneously administered Darbepoetin alfa has a half-life two to three times longer than that of recombinant human erythropoietin (rHuEPO) at approximately allowing physicians to dose less frequently while maintaining an equivalent biological response for CKD and oncology patients.

Clinically Equivalent to rHuEPO with Superior Convenience: Results from clinical studies in patients with chronic renal failure have shown that Darbepoetin alfa is equivalent to rHuEPO in terms of onset of action, increases in haemoglobin concentration, and percentage of patients achieving target haemoglobin concentration, although Darbepoetin alfa is administered less frequently once weekly or every other week.

Measurable Improvement in 2–6 Weeks: Patients will be able to notice an increase in the count of red blood cells (haemoglobin levels) in 2 to 6 weeks of starting Cresp 40 Injection providing measurable, tangible relief from anaemia symptoms including fatigue, weakness, breathlessness, and pallor within a clinically meaningful timeframe.

Improves Quality of Life: By addressing anaemia and its associated symptoms, Cresp 40 Injection can enhance the overall wellbeing and quality of life for individuals undergoing treatment for chronic kidney disease or cancer helping patients feel stronger, more active, and significantly better during their treatment journey.

Sterile, Preservative-Free Single-Dose Vial: Cresp is supplied in sterile, preservative-free, non-pyrogenic single-dose vials ensuring maximum safety, sterility, and precision dosing with zero risk of preservative-related adverse reactions for every injection administered.

Indications:

Cresp 40mcg Injection is indicated for the treatment of:

• Symptomatic anaemia associated with Chronic Renal Failure (CRF) in adult and paediatric patients on and not on dialysis
• Chemotherapy-induced anaemia in adult patients with non-myeloid malignancies receiving multi-cycle chemotherapy
• Anaemia in certain surgical patients to reduce the need for allogeneic blood transfusions (as directed by physician)

Precautions:

• Cresp 40mcg Injection is not recommended for use in patients with high blood pressure which is not being controlled with other medicines.
• Patients may not respond to Cresp 40 Injection if they have deficiencies of iron, folic acid, or Vitamin B12. It is important to correct these deficiencies before or during treatment.
• Cresp 40 Injection can enhance the risk of serious heart problems including heart attack inform your doctor immediately if you notice shortness of breath, sudden numbness or weakness, chest pain, or trouble speaking or understanding.
• Darbepoetin alfa may cause a serious type of allergic reaction called anaphylaxis, which can be life-threatening and requires immediate medical attention.
• Inform your doctor of all current medications before starting Cresp, as drug interactions may affect its efficacy and safety.
• Use with caution in patients with liver disease, seizure history, sickle cell anaemia, or bone marrow conditions.
• Using Cresp 40 Injection during pregnancy or while nursing may be dangerous consult your healthcare provider before use.

Side Effects:

Common side effects may include:

• Headache
• Nausea or vomiting
• Diarrhoea or abdominal pain
• High blood pressure (hypertension)
• Injection site reactions redness, pain, or swelling
• Shortness of breath or cough
• Low blood pressure during dialysis
• Joint or muscle pain
• Peripheral oedema (swelling of limbs)

Stop receiving Cresp and contact your doctor immediately if you experience severe headache, drowsiness, confusion, eyesight problems, nausea, vomiting or fits (which could indicate very high blood pressure), or if you develop serious skin rashes such as Stevens-Johnson syndrome or toxic epidermal necrolysis.

Storage:

Store Cresp Injection at a temperature of 2°C to 8°C. Keep this medicine away from light. Keep it out of the reach of children and pets. Do not freeze. Do not shake. Always check the expiry date before use. Do not use if the solution appears discoloured, cloudy, or contains visible particles. Dispose of used vials and syringes safely in an approved sharps container.

About the Brand Dr. Reddy's Laboratories Ltd.:

Dr. Reddy's Laboratories Ltd. is one of India's most esteemed and globally recognised pharmaceutical companies, headquartered in Hyderabad, Telangana. With decades of commitment to delivering high-quality, affordable, and innovative medicines across multiple therapeutic areas, Dr. Reddy's has earned the trust of healthcare professionals and patients worldwide. Their unwavering focus on pharmaceutical excellence, patient safety, and clinical innovation aligns perfectly with Animeal's commitment to offering every customer the most reliable, high-quality medicines and healthcare products available.

Disclaimer:

While Animeal provides expert-reviewed and accurate product information, Cresp 40mcg Injection is a prescription-only pharmaceutical product that must be administered strictly under the supervision of a qualified and experienced healthcare professional. This information is intended for general awareness only and does not constitute medical advice. Never self-administer this injection without proper medical training and explicit prescription from your doctor. Do not alter your prescribed dose or frequency without consulting your physician. For emergencies or severe side effects, seek immediate medical attention. Keep this and all medicines out of reach of children.