Zydus Duromect Injection, 10ml

Broad-Spectrum Single-Injection Parasite Control:
A single administration of Duromect targets a comprehensive range of both internal parasites (roundworms, lungworms, eyeworms) and external parasites (mites, lice, ticks, screwworms) simultaneously, eliminating the need for multiple antiparasitic agents and simplifying treatment protocols for veterinarians managing complex or mixed infestations. This dual internal and external efficacy within one injection is a defining advantage of Doramectin over narrower-spectrum antiparasitics.

Extended Duration of Action and Persistent Protection:
The lipophilic oily depot formulation ensures that Doramectin is absorbed gradually from the injection site, maintaining effective plasma concentrations for extended periods following a single dose. This persistent pharmacokinetic profile provides protection against reinfestation after treatment, with documented protective intervals of up to 35 days against Ostertagia ostertagi and Dictyocaulus viviparus in cattle, up to 28 days against Haemonchus placei and sucking lice, and up to 42 days against Psoroptes bovis mange mites, substantially reducing the frequency of retreatment required.

Safe for Use in Ivermectin-Sensitive Breeds:
One of the most clinically significant distinguishing features of Duromect is its reported safety profile in dog breeds carrying the MDR1 (ABCB1) gene mutation, such as Collies, Shetland Sheepdogs, Australian Shepherds, and related herding breeds. These breeds are known to have increased blood-brain barrier permeability to many macrocyclic lactones, particularly ivermectin. Doramectin, used at veterinarian-prescribed doses via the subcutaneous route, has been documented in literature to be tolerable in these sensitive breeds for the treatment of generalised demodicosis, making it a valuable clinical option where ivermectin may be contraindicated.

Low-Volume Injection for Minimal Animal Stress:
Duromect is a concentrated, low-volume formulation that delivers the full therapeutic dose in a small injection volume, reducing the physical burden on the animal and minimising tissue trauma at the injection site. For livestock operations requiring treatment of large numbers of animals, this translates to faster administration, reduced animal handling stress, and improved operator efficiency without compromising treatment efficacy.

Supports Herd Health, Productivity, and Weight Performance:
In livestock, parasitic burdens are a primary cause of impaired feed conversion, reduced weight gain, decreased milk production, and compromised reproductive performance. By systematically eliminating both internal and external parasites, regular strategic use of Duromect as part of a veterinarian-guided parasite management programme directly supports the productive capacity and overall health of your herd, delivering measurable economic and welfare benefits.

How to Use:

Duromect Doramectin Injection must be administered exclusively by a qualified veterinarian or veterinary professional and must not be self-administered by animal owners or farm workers without direct veterinary instruction and supervision. The product is a pale yellow, ready-to-use sterile solution supplied in 10 ml and 50 ml vials. For cattle, sheep, and goats, the injection is administered via the intramuscular or subcutaneous route at a dosage rate corresponding to body weight, with the neck region being the recommended site for cattle to comply with Beef Quality Assurance guidelines. For swine, the injection is given by the intramuscular route only. For dogs and cats in cases of generalised demodicosis, administration is by the subcutaneous route at the dosage and frequency determined by the attending veterinarian. The exact dose must always be calculated based on a current, accurate body weight; underdosing may result in treatment failure and can contribute to the development of parasite resistance. Use a clean needle for each injection and withdraw from the vial aseptically. Do not mix with other products in the same syringe. Sheep and goats should be vaccinated against enterotoxemia or pulpy kidney disease before treatment with Duromect. Vaccination against broad-spectrum Clostridium infections is strongly recommended in cattle, sheep, and goats prior to or concurrent with treatment. The number of withdrawals from a single vial must not exceed ten.

Storage Advice

Store unopened Duromect Doramectin Injection vials in a cool, dry place below 30 degrees C, away from direct sunlight and heat sources. Do not freeze. Once a vial has been broached, reseal immediately after withdrawal using a clean sterile needle to maintain aseptic conditions, and do not exceed ten withdrawals from any single vial. Store broached vials under the same temperature conditions and use within the period recommended by your veterinarian. Do not use after the best-before date printed on the vial label or outer carton. Keep out of reach of uninformed persons and children at all times.

About the Brand:

Zydus AHL (Zydus Animal Health and Investments Limited) is the animal health division of Zydus Lifesciences Limited, formerly known as Cadila Healthcare Limited, a fully integrated Indian pharmaceutical group with origins tracing back to 1952 and an operational presence in animal health spanning more than six decades. As one of India's leading animal health companies, Zydus AHL holds leadership positions across antimicrobials, vitamin injectables, corticosteroids, hormones, anti-mastitis products, and antiparasitic formulations, supported by the Zydus Group's state-of-the-art Pharmaceutical Technology Centre, which drives new product development, novel delivery research, and rigorous stability and toxicological testing. Zydus AHL operates through species-based strategic business units supported by a technically trained field force that provides round-the-clock veterinary and agricultural support across India, and has partnered globally with Phibro AHC for co-marketing of international animal health products, reflecting a product philosophy grounded in comprehensive health coverage, quality manufacturing, and cost-effective innovation that aligns with Animeal's commitment to offering only trusted, evidence-based pharmaceutical solutions for your animals. Discover Zydus AHL today.

Disclaimer:

Please note that while Duromect Doramectin Injection is formulated from pharmaceutical-grade Doramectin (10 mg/ml) with Benzyl Alcohol as preservative in an oily base, and is appropriate for use in cattle, sheep, goats, swine, dogs, and cats under veterinary supervision, it is a prescription-only injectable parasiticide and must not be purchased, stored, or administered without a valid veterinary prescription and direct veterinary oversight. This product is not a complete antiparasitic solution in isolation; it must be used as part of a veterinarian-guided, integrated parasite management programme that accounts for local parasite resistance patterns, seasonal epidemiology, and species-specific risk factors. Meat withdrawal periods apply: 28 days for meat and 7 days for milk in livestock; treated animals must not be slaughtered for human consumption before the expiry of these periods. This product must not be used in animals producing milk for human consumption. For pets and livestock with known or suspected MDR1 gene mutations, hepatic disease, or prior hypersensitivity to macrocyclic lactones, consult your veterinarian before introducing this product. Animeal supports your pet's health and happiness journey but does not replace the advice of a qualified veterinary professional.