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INJECTABLE
EVATOCIN INJ
EVATOCIN INJ
By NEON
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About Product
Evatocin INJ by Neon Laboratories Ltd. is a sterile, synthetic oxytocin injection containing 5 IU of oxytocin per mL, formulated to address one of the most clinically critical challenges in veterinary obstetrics and post-partum care: inadequate uterine contractility and impaired milk let-down in livestock and companion animals. Whether supporting the progression of labour in cattle, buffalo, sheep, goats, and sows, managing post-partum uterine complications, or facilitating milk ejection in lactating dams, Evatocin INJ delivers the precise oxytocic action required at the most decisive moments in an animal's reproductive cycle. As a Schedule H prescription-only parenteral medicine, it is intended for use under the strict supervision and direction of a qualified veterinarian. Animeal is proud to offer Evatocin INJ as part of its comprehensive range of veterinarian-trusted reproductive health solutions for livestock and companion animal care across India.
Ingredients:
Oxytocin (Synthetic) 5 IU per mL: Oxytocin (cyclo[1-6]-L-cystyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cystyl-L-prolyl-L-leucyl-glycinamide) is a nonapeptide neurohypophysial hormone that is produced endogenously in the magnocellular neurosecretory cells of the hypothalamus and released via the posterior pituitary gland. In Evatocin INJ, the synthetic equivalent replicates the biological activity of endogenous oxytocin with high precision and purity. Upon intramuscular or intravenous administration, oxytocin binds to specific G-protein coupled oxytocin receptors (OTRs) on the smooth muscle cells of the uterine myometrium, triggering activation of phospholipase C, release of intracellular calcium, and ultimately the coordinated rhythmic contraction of uterine smooth muscle essential for the expulsion of the fetus and placenta during parturition. The density and sensitivity of myometrial OTRs increases dramatically during late gestation under oestrogen priming, which is why oxytocin's effect on the uterus is markedly stronger near and at term than during early pregnancy. In the mammary gland, oxytocin targets the myoepithelial cells surrounding the alveoli, stimulating their contraction to force milk from the alveolar ducts into the major ducts and cisterns a process referred to as milk let-down or the milk ejection reflex provided the udder is in a physiologically ready state. Synthetic oxytocin used in Evatocin INJ is produced by solid-phase peptide synthesis to pharmaceutical purity standards, ensuring consistent potency, absence of vasopressin-like pressor contamination, and reliable clinical performance in every vial.
Sodium Chloride (as Isotonic Carrier): Sodium chloride (NaCl) at physiological concentration (0.9% w/v) is used as the aqueous vehicle for the oxytocin solution, ensuring isotonicity with body fluids to prevent cellular damage or discomfort at the injection site and to maintain the solubility and stability of the oxytocin peptide in solution.
Chlorobutanol (as Preservative): Chlorobutanol (1,1,1-trichloro-2-methyl-2-propanol) at 0.5% w/v functions as a broad-spectrum antimicrobial preservative in the multi-dose vial formulation, maintaining sterility against bacterial and fungal contamination across the usage life of the opened vial without compromising the bioactivity of the oxytocin molecule.
Features and Benefits
Precise Uterine Stimulation at the Critical Mom...
Precise Uterine Stimulation at the Critical Moment of Parturition:
Evatocin INJ delivers synthetic oxytocin at a clinically targeted 5 IU/mL concentration, providing the veterinarian with a reliable and controllable uterotonic tool during the most time-sensitive phase of an animal's reproductive life. By binding directly to myometrial oxytocin receptors, it initiates and sustains the rhythmic, coordinated uterine contractions needed to complete delivery safely reducing the duration of dystocia and the risk of fetal compromise in affected animals.
Supports Complete Post-Partum Uterine Recovery:
The post-partum period is one of the highest-risk windows for uterine disease in livestock. Evatocin INJ targets the atonic, poorly involuting uterus by restoring its contractile activity facilitating the expulsion of retained placenta, clearing the uterine environment of debris and pathogens, and accelerating the involution process that underpins a prompt return to the reproductive cycle. This makes it a critical tool in reducing the incidence of metritis, endometritis, and post-partum infertility in dairy and breeding herds.
Restores Milk Let-Down in Lactating Dams:
Failure of milk ejection whether due to post-partum stress, inadequate udder stimulation, or physiological disruption can have significant consequences for both neonatal nutrition and dairy productivity. Evatocin INJ restores the milk let-down reflex by directly stimulating the myoepithelial cells of the mammary alveoli, facilitating the release of stored milk into the duct system for efficient nursing or milking, provided the mammary gland is in an appropriate physiological state.
Sterile, Consistent-Potency Parenteral Formulation:
Manufactured by Neon Laboratories Ltd. to rigorous pharmaceutical GMP standards, Evatocin INJ provides a sterile, clearly specified 5 IU/mL oxytocin concentration in a stable aqueous solution ensuring that every dose administered under veterinary prescription delivers precisely predictable and reproducible pharmacological action with minimal pressor activity, reducing the risk of cardiovascular side effects associated with impure or inconsistently potent oxytocin preparations.
Broad Species Applicability in a Single Formulation:
Evatocin INJ is clinically appropriate for a wide range of species including cattle, buffalo, horses, sheep, goats, sows, dogs, and cats making it a versatile and practical single-agent solution for the veterinarian managing reproductive emergencies and post-partum complications across both large and small animal practice.
Usage and Applications
How to Use:Evatocin INJ must be administered ex...
How to Use:
Evatocin INJ must be administered exclusively by a qualified and registered veterinarian. It is formulated for intramuscular (I/M), subcutaneous (S/C), or intravenous (I/V) administration as determined by the attending veterinarian based on clinical indication and urgency. The injection site should be prepared with standard aseptic technique using a sterile needle and syringe for each administration. The vial must be inspected visually before use and must not be administered if the solution appears discoloured, cloudy, or contains visible particulate matter. Dosage is strictly species- and indication-specific and must be determined by the prescribing veterinarian based on body weight, clinical assessment, stage of parturition or lactation, and concurrent medications. Evatocin INJ must not be used in cases of obstructive dystocia, abnormal fetal presentation prior to correction, an unopened or rigid cervix, or where vaginal delivery is contraindicated administration in these situations carries serious risk of uterine rupture and fetal compromise. This product is a Schedule H prescription-only veterinary medicine and may only be dispensed and administered against a valid prescription issued by a registered veterinary practitioner. All dosing records should be maintained and monitored to ensure safe and appropriate use.
Storage Advice:
Store unopened Evatocin INJ in a cool, dry place below 25°C, away from direct sunlight and heat sources. Do not freeze freezing degrades the peptide structure of oxytocin and renders it ineffective. Once opened, the multi-dose vial should be handled under strict aseptic conditions; re-seal with the original sterile stopper after each withdrawal, store under the same temperature conditions, and use within the period recommended on the label. As a controlled prescription injectable, store in a secure location accessible only to authorised veterinary personnel. Do not use after the best-before date printed on the vial and outer carton.
About the Brand:
Neon Laboratories Ltd. is a trusted, Mumbai-based Indian pharmaceutical company incorporated in 1982, with a long-standing reputation as a specialist manufacturer of high-quality parenteral formulations including anaesthetics, critical care injectables, and gynaecological products across both human and veterinary medicine. With three WHO-GMP-compliant manufacturing facilities, more than 14 Indian and global patents, and a product portfolio spanning anesthesiology, oncology, cardiology, and gynaecology, Neon has built its identity as a precision-focused parenteral pharmaceutical manufacturer guided by an uncompromising commitment to Total Quality Management. Their dedication to developing affordable, reliable, clinically essential injectable medicines including reproductive health products such as Evatocin INJ reflects a philosophy of putting patient and animal outcomes first, backed by rigorous science and manufacturing excellence. This commitment to quality-driven pharmaceutical manufacturing aligns with Animeal's mission to offer only the most dependable, veterinarian-trusted clinical products to animal caregivers and livestock managers across India discover Neon Laboratories today.
Disclaimer:
Please note that while Evatocin INJ is formulated from synthetic oxytocin and is appropriate for use in cattle, buffalo, horses, sheep, goats, sows, dogs, and cats for obstetric and lactation-related indications, it is a Schedule H prescription-only injectable veterinary medicine and must not be purchased, possessed, or administered without a valid prescription from a registered veterinary practitioner. This product must be administered only by a qualified veterinarian self-administration or administration by untrained personnel carries serious risk of harm to the animal, including uterine rupture, fetal distress, and cardiovascular complications. Evatocin INJ is a targeted reproductive health agent and is not a substitute for comprehensive obstetric assessment, diagnosis, or management. For animals with a history of hypersensitivity to oxytocin, hypocalcaemia, hypoglycaemia, cardiovascular compromise, or any condition where uterine contraction is contraindicated, consult your veterinarian before administering this product. Animeal supports your pet's health and happiness journey but does not replace the advice of a qualified veterinary professional.
