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LEMASOL-75 INJ

LEMASOL-75 INJ

By ZENEX AH

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Lemasol-75 Injection is a standout product in our VETERINARY ANTHELMINTIC INJECTABLE category. Manufactured to strict pharmaceutical-grade standards, Lemasol-75 delivers Levamisole Hydrochloride at the highly concentrated 75mg/ml strength in a convenient, ready-to-use 30ml multi-dose vial format making it the ideal anthelmintic injectable for large animal field veterinary practice, livestock farm management, and veterinary clinic use. Levamisole Hydrochloride is a member of the imidazothiazole chemical class of anthelmintics a completely distinct chemical class from benzimidazoles (Albendazole, Fenbendazole), macrocyclic lactones (Ivermectin, Doramectin), and tetrahydropyrimidines (Pyrantel) making it an invaluable rotation partner in integrated parasite management programmes designed to delay and manage the growing problem of anthelmintic resistance in Indian livestock. Beyond its potent nematocidal activity, Levamisole's unique additional immunostimulant property which restores depressed cell-mediated immune function and enhances antibody titre in treated animals provides the added benefit of improved resistance to infectious diseases including FMD and Rinderpest in livestock recovering from parasitic infestation and associated immunosuppression. With Lemasol-75, veterinarians and livestock managers can trust a pharmaceutical-grade, reliably dosed, and clinically versatile parenteral nematocide for comprehensive worm control across their entire animal caseload.

Composition:

  • Levamisole Hydrochloride 75mg/ml (Active Ingredient): the pure L-isomer of Tetramisole, Levamisole Hydrochloride is a potent nicotinic acetylcholine receptor agonist that exerts its nematocidal activity through a dual pharmacological mechanism. The primary mechanism involves selective stimulation of nicotinic acetylcholine receptors at the neuromuscular junction of susceptible nematode parasites causing irreversible depolarisation and spastic paralysis of the nematode musculature. Unlike the flaccid paralysis produced by macrocyclic lactones (which act on glutamate-gated chloride channels), Levamisole produces spastic (tonic) paralysis the paralysed nematode is unable to maintain its position in the intestinal lumen and is expelled by normal intestinal peristalsis within hours of treatment. The secondary mechanism involves inhibition of the nematode's fumarate reductase enzyme a key enzyme in the parasite's anaerobic energy metabolism pathway disrupting ATP production and further compromising nematode survival. Together, these two complementary mechanisms ensure rapid, complete, and irreversible nematode death within 12 to 24 hours of administration. The imidazothiazole chemical class of Levamisole has a completely distinct mechanism of action from all three other major anthelmintic classes making it the most important rotation partner in anthelmintic resistance management programmes
  • Levamisole's Additional Immunostimulant Property: beyond its primary nematocidal activity, Levamisole exerts a unique and clinically valuable immunomodulatory effect specifically the restoration of depressed cell-mediated immune function in immunocompromised, debilitated, or parasitosis-weakened animals. At sub-anthelmintic doses, Levamisole stimulates T-lymphocyte proliferation and maturation, enhances phagocytic activity of monocytes and macrophages, and increases antibody titre production providing meaningful immunological restoration in animals whose immune competence has been suppressed by heavy parasitic infestation, nutritional deficiency, or chronic disease. This immunostimulant benefit translates clinically into improved resistance to secondary bacterial and viral infections including FMD and Rinderpest in livestock recovering from significant nematode burdens
  • Aqueous Vehicle with Stabilisers: a pharmaceutical-grade aqueous injection base incorporating appropriate pH buffering agents and stabilisers that ensure chemical stability of the Levamisole Hydrochloride active ingredient throughout the entire shelf life of the vial, maintain the pH of the solution within the optimal range for subcutaneous tolerability, and provide a completely clear, colourless injectable solution free from particulate matter

Broad Gastrointestinal Nematode Spectrum Cattle, Buffaloes & Sheep: Lemasol-75 provides clinically reliable coverage against all major gastrointestinal nematode species affecting Indian cattle, buffaloes, and sheep including Haemonchus contortus (Barber's Pole Worm the most economically important), Ostertagia spp., Trichostrongylus spp., Cooperia spp., Nematodirus spp., Bunostomum spp. (hookworm), Oesophagostomum spp. (nodular worm), Chabertia spp., and Neoascaris vitulorum in young calves

Pulmonary Nematode (Lungworm) Control Dictyocaulus spp. one of Levamisole's most clinically important advantages over benzimidazoles in cattle and sheep practice reliable efficacy against Dictyocaulus viviparus (bovine lungworm) and Dictyocaulus filaria (ovine lungworm) the causative agents of parasitic bronchitis (husk, hoose) that cause severe coughing, respiratory distress, and significant production losses and mortality in young cattle and sheep

Comprehensive Swine Nematode Coverage: effective against the major gastrointestinal and pulmonary nematode species in Indian pigs including Ascaris suum, Oesophagostomum spp., Strongyloides ransomi, Stephanurus dentatus (kidney worm), and the lung nematodes Metastrongylus spp. (swine lungworm)

Companion Animal Endoparasiticide Applications: under veterinary prescription and with careful weight-based dosing, Levamisole is used in dogs for the treatment of roundworm (Toxocara canis, Toxascaris leonina) and hookworm (Ancylostoma caninum, Uncinaria stenocephala) infestations, and historically as a microfilaricide in the management of Dirofilaria immitis (heartworm) microfilariae a use requiring specialist veterinary supervision given the narrow safety margin in dogs

Unique Immunostimulant Benefit for Disease Resistance: the restoration of depressed cell-mediated immunity and enhanced antibody titre production that Levamisole provides to treated animals represents a meaningful clinical benefit beyond simple parasite elimination actively improving livestock resistance to major infectious diseases including FMD, Rinderpest, and secondary bacterial pneumonia that commonly complicate or follow significant parasitic infestations

Critical Anthelmintic Rotation Partner for Resistance Management: the imidazothiazole mechanism of action of Levamisole is completely distinct from benzimidazoles, macrocyclic lactones, and tetrahydropyrimidines making Lemasol-75 the most important strategic rotation anthelmintic for Indian livestock veterinarians and farmers implementing integrated parasite management programmes designed to delay, detect, and manage anthelmintic resistance in their herds

Rapid Onset Injectable Delivery for Maximum Bioavailability: the injectable delivery route ensures complete, predictable systemic bioavailability unaffected by variable gastrointestinal absorption, poor compliance with oral drenching, or the significant reduction in efficacy caused by feeding immediately before oral Levamisole administration making the injectable formulation the preferred choice for guaranteed therapeutic blood levels in field conditions

Convenient 30ml Multi-Dose Vial for Field & Farm Use: the 30ml vial provides sufficient volume for multiple large animal treatments at a single farm visit, reducing the number of vials required for routine herd deworming and minimising pharmaceutical waste in field practice

How to Use:

For subcutaneous (S/C) injection in large animals administered by or under the direct supervision of a licensed veterinarian only. In large animals, the preferred injection site is the side of the neck or pre-scapular region. Draw the required dose into a clean, sterile syringe using aseptic technique. Administer by slow subcutaneous injection, distributing large-volume doses across multiple injection sites in the same animal to minimise local tissue reaction and improve drug absorption. In dogs, administer by subcutaneous injection only never intravenously. In large animals, mild localised swelling at the injection site may occur and typically resolves within 7 to 14 days.

Storage Advice:

Store Lemasol-75 Injection below 25°C in a cool, dark, dry place. Protect strictly from direct sunlight Levamisole Hydrochloride is photosensitive and light exposure causes gradual potency degradation. Keep the vial cap tightly sealed between uses. Do not freeze. Keep out of reach of children. Do not use after the expiry date printed on the vial label and outer carton. Use aseptic technique for every dose drawn from the multi-dose vial to maintain sterility throughout the in-use period.

About the Brand:

Lemasol-75 is manufactured by a trusted Indian veterinary pharmaceutical company with a strong track record of delivering quality-assured, GMP-compliant veterinary injectable formulations to veterinarians, livestock farmers, and animal health professionals across India. With a formulation philosophy rooted in pharmaceutical precision, reliable active ingredient concentration accuracy, and accessible pricing that supports routine large animal herd deworming at the farm level, the manufacturer ensures that every vial of Lemasol-75 delivers the consistent potency and sterility that veterinarians and livestock managers depend upon for reliable therapeutic outcomes. Their commitment to accessible, quality-assured veterinary anthelmintic care aligns perfectly with Animeal's mission to provide registered veterinary professionals and livestock operators across India with reliable access to the full spectrum of veterinary pharmaceutical needs.

Disclaimer:

Lemasol-75 Injection is a prescription-only veterinary injectable anthelmintic that must be prescribed and administered exclusively by or under the direct supervision of a licensed veterinarian. It is not available for general retail sale or self-administration. Levamisole has a relatively narrow safety margin particularly in dogs where neurotoxicity including panting, trembling, and behavioural changes has been reported at doses slightly above the recommended therapeutic range. Do not use concurrently with Pyrantel both agents act via nicotinic acetylcholine receptor agonism and concurrent use significantly increases the risk of cholinergic toxicity. Do not use in lactating dairy animals without veterinary guidance. Do not use in severely debilitated, renally or hepatically impaired animals without veterinary assessment. Observe all meat and milk withholding periods strictly. Resistance of gastrointestinal nematodes to Levamisole is a growing concern in livestock regular faecal egg count reduction testing is recommended to monitor anthelmintic efficacy. Animeal facilitates enquiry and procurement for registered veterinary professionals only. Always refer to the current product prescribing information and your clinical judgement for complete prescribing, administration, and withholding period guidance.

Q: What is Levamisole's mechanism of action and why does it differ from Ivermectin and Albendazole?
Levamisole's primary nematocidal mechanism is nicotinic acetylcholine receptor agonism at the nematode neuromuscular junction causing irreversible spastic (tonic) paralysis of the worm's body musculature, followed by expulsion from the gut by intestinal peristalsis within hours. This is completely distinct from Ivermectin's mechanism which act on glutamate-gated chloride channels causing flaccid (not spastic) paralysis and from Albendazole's mechanism which inhibits tubulin polymerisation disrupting the nematode's cytoskeletal structure. Since resistance develops specifically to each individual mechanism of action, Levamisole's completely different target site means that nematode populations that have developed resistance to Ivermectin or Albendazole remain fully susceptible to Levamisole, making it the essential rotation and combination partner in managing multi-drug resistance in Indian livestock.
Q: What is the immunostimulant benefit of Levamisole and which animals benefit most?
Levamisole's immunostimulant effect involves restoration of depressed cell-mediated immune function specifically stimulation of T-lymphocyte maturation and proliferation, enhanced phagocytic activity of monocytes and macrophages, and increased antibody titre production. This effect is most pronounced and clinically meaningful in immunocompromised animals including livestock with heavy parasitic burdens, animals recovering from illness or nutritional deficiency, young animals with immature immune systems, and stressed animals following transport or environmental challenges. In these patients, the immunostimulant benefit of Levamisole translates into improved resistance to secondary infections including FMD and Rinderpest, faster clinical recovery, and improved overall disease resistance following anthelmintic treatment. In healthy, immunocompetent animals, the immunostimulant effect is less pronounced.
Q: Why must Levamisole never be combined with Pyrantel in dogs?
Levamisole and Pyrantel share the same pharmacological mechanism of action both are nicotinic acetylcholine receptor agonists at the nematode neuromuscular junction. However, because the nicotinic acetylcholine receptors targeted by both drugs are not completely nematode-specific, both agents also have some activity at mammalian nicotinic receptors at high plasma concentrations. When both drugs are administered concurrently, their combined cholinergic receptor stimulation produces additive and potentially synergistic toxicity in the treated animal, significantly increasing the risk of cholinergic adverse effects including excessive salivation, lacrimation, muscle tremors, ataxia, and in severe cases respiratory depression and collapse. This combination is therefore strictly contraindicated in all animal species.
Q: What are the most important safety precautions when using Lemasol-75 in dogs?
Levamisole has a significantly narrower safety margin in dogs than in large animals the therapeutic dose and the toxic dose are closer together, meaning dosing errors have more serious clinical consequences. Key precautions include: always weigh the dog accurately before calculating the dose rather than estimating; never exceed the maximum recommended dose of 10mg/kg in dogs; monitor closely for signs of neurotoxicity including panting, trembling, agitation, salivation, and behavioural changes in the first 2 hours post-injection; do not combine with Pyrantel; use with extreme caution or avoid entirely in Collies and related herding breeds that may carry the MDR1/ABCB1 gene mutation causing elevated central nervous system drug sensitivity; always administer subcutaneously never intravenously; and have atropine available for management of cholinergic toxicity if required.
Q: How can veterinary clinics and livestock operators procure Lemasol-75 Injection through Animeal?
Registered veterinary practitioners, veterinary clinics, animal hospitals, and authorised livestock farm operators can enquire about and procure Lemasol-75 Injection through Animeal's dedicated veterinary pharmaceutical enquiry channel. Please use the Enquire Now button on this product page or contact our veterinary pharma team directly via WhatsApp or phone with your valid veterinary prescription and practice or farm registration details. Our team will respond promptly with product availability, current pricing, pack size options, and delivery arrangements to your registered practice, clinic, or farm address anywhere across India.
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LEMASOL-75 INJ

By ZENEX AH
₹ 75.60
You save ₹ 8.40 (10%)
MRP ₹ 84.00 (Incl. taxes)

Out of Stock

Expires on or after: Feb, 2026
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₹ 75.60
MRP ₹ 84.00  10% OFF
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Lemasol-75 Injection is a standout product in our VETERINARY ANTHELMINTIC INJECTABLE category. Manufactured to strict pharmaceutical-grade standards, Lemasol-75 delivers Levamisole Hydrochloride at the highly concentrated 75mg/ml strength in a convenient, ready-to-use 30ml multi-dose vial format making it the ideal anthelmintic injectable for large animal field veterinary practice, livestock farm management, and veterinary clinic use. Levamisole Hydrochloride is a member of the imidazothiazole chemical class of anthelmintics a completely distinct chemical class from benzimidazoles (Albendazole, Fenbendazole), macrocyclic lactones (Ivermectin, Doramectin), and tetrahydropyrimidines (Pyrantel) making it an invaluable rotation partner in integrated parasite management programmes designed to delay and manage the growing problem of anthelmintic resistance in Indian livestock. Beyond its potent nematocidal activity, Levamisole's unique additional immunostimulant property which restores depressed cell-mediated immune function and enhances antibody titre in treated animals provides the added benefit of improved resistance to infectious diseases including FMD and Rinderpest in livestock recovering from parasitic infestation and associated immunosuppression. With Lemasol-75, veterinarians and livestock managers can trust a pharmaceutical-grade, reliably dosed, and clinically versatile parenteral nematocide for comprehensive worm control across their entire animal caseload.

Composition:

  • Levamisole Hydrochloride 75mg/ml (Active Ingredient): the pure L-isomer of Tetramisole, Levamisole Hydrochloride is a potent nicotinic acetylcholine receptor agonist that exerts its nematocidal activity through a dual pharmacological mechanism. The primary mechanism involves selective stimulation of nicotinic acetylcholine receptors at the neuromuscular junction of susceptible nematode parasites causing irreversible depolarisation and spastic paralysis of the nematode musculature. Unlike the flaccid paralysis produced by macrocyclic lactones (which act on glutamate-gated chloride channels), Levamisole produces spastic (tonic) paralysis the paralysed nematode is unable to maintain its position in the intestinal lumen and is expelled by normal intestinal peristalsis within hours of treatment. The secondary mechanism involves inhibition of the nematode's fumarate reductase enzyme a key enzyme in the parasite's anaerobic energy metabolism pathway disrupting ATP production and further compromising nematode survival. Together, these two complementary mechanisms ensure rapid, complete, and irreversible nematode death within 12 to 24 hours of administration. The imidazothiazole chemical class of Levamisole has a completely distinct mechanism of action from all three other major anthelmintic classes making it the most important rotation partner in anthelmintic resistance management programmes
  • Levamisole's Additional Immunostimulant Property: beyond its primary nematocidal activity, Levamisole exerts a unique and clinically valuable immunomodulatory effect specifically the restoration of depressed cell-mediated immune function in immunocompromised, debilitated, or parasitosis-weakened animals. At sub-anthelmintic doses, Levamisole stimulates T-lymphocyte proliferation and maturation, enhances phagocytic activity of monocytes and macrophages, and increases antibody titre production providing meaningful immunological restoration in animals whose immune competence has been suppressed by heavy parasitic infestation, nutritional deficiency, or chronic disease. This immunostimulant benefit translates clinically into improved resistance to secondary bacterial and viral infections including FMD and Rinderpest in livestock recovering from significant nematode burdens
  • Aqueous Vehicle with Stabilisers: a pharmaceutical-grade aqueous injection base incorporating appropriate pH buffering agents and stabilisers that ensure chemical stability of the Levamisole Hydrochloride active ingredient throughout the entire shelf life of the vial, maintain the pH of the solution within the optimal range for subcutaneous tolerability, and provide a completely clear, colourless injectable solution free from particulate matter

Broad Gastrointestinal Nematode Spectrum Cattle, Buffaloes & Sheep: Lemasol-75 provides clinically reliable coverage against all major gastrointestinal nematode species affecting Indian cattle, buffaloes, and sheep including Haemonchus contortus (Barber's Pole Worm the most economically important), Ostertagia spp., Trichostrongylus spp., Cooperia spp., Nematodirus spp., Bunostomum spp. (hookworm), Oesophagostomum spp. (nodular worm), Chabertia spp., and Neoascaris vitulorum in young calves

Pulmonary Nematode (Lungworm) Control Dictyocaulus spp. one of Levamisole's most clinically important advantages over benzimidazoles in cattle and sheep practice reliable efficacy against Dictyocaulus viviparus (bovine lungworm) and Dictyocaulus filaria (ovine lungworm) the causative agents of parasitic bronchitis (husk, hoose) that cause severe coughing, respiratory distress, and significant production losses and mortality in young cattle and sheep

Comprehensive Swine Nematode Coverage: effective against the major gastrointestinal and pulmonary nematode species in Indian pigs including Ascaris suum, Oesophagostomum spp., Strongyloides ransomi, Stephanurus dentatus (kidney worm), and the lung nematodes Metastrongylus spp. (swine lungworm)

Companion Animal Endoparasiticide Applications: under veterinary prescription and with careful weight-based dosing, Levamisole is used in dogs for the treatment of roundworm (Toxocara canis, Toxascaris leonina) and hookworm (Ancylostoma caninum, Uncinaria stenocephala) infestations, and historically as a microfilaricide in the management of Dirofilaria immitis (heartworm) microfilariae a use requiring specialist veterinary supervision given the narrow safety margin in dogs

Unique Immunostimulant Benefit for Disease Resistance: the restoration of depressed cell-mediated immunity and enhanced antibody titre production that Levamisole provides to treated animals represents a meaningful clinical benefit beyond simple parasite elimination actively improving livestock resistance to major infectious diseases including FMD, Rinderpest, and secondary bacterial pneumonia that commonly complicate or follow significant parasitic infestations

Critical Anthelmintic Rotation Partner for Resistance Management: the imidazothiazole mechanism of action of Levamisole is completely distinct from benzimidazoles, macrocyclic lactones, and tetrahydropyrimidines making Lemasol-75 the most important strategic rotation anthelmintic for Indian livestock veterinarians and farmers implementing integrated parasite management programmes designed to delay, detect, and manage anthelmintic resistance in their herds

Rapid Onset Injectable Delivery for Maximum Bioavailability: the injectable delivery route ensures complete, predictable systemic bioavailability unaffected by variable gastrointestinal absorption, poor compliance with oral drenching, or the significant reduction in efficacy caused by feeding immediately before oral Levamisole administration making the injectable formulation the preferred choice for guaranteed therapeutic blood levels in field conditions

Convenient 30ml Multi-Dose Vial for Field & Farm Use: the 30ml vial provides sufficient volume for multiple large animal treatments at a single farm visit, reducing the number of vials required for routine herd deworming and minimising pharmaceutical waste in field practice

How to Use:

For subcutaneous (S/C) injection in large animals administered by or under the direct supervision of a licensed veterinarian only. In large animals, the preferred injection site is the side of the neck or pre-scapular region. Draw the required dose into a clean, sterile syringe using aseptic technique. Administer by slow subcutaneous injection, distributing large-volume doses across multiple injection sites in the same animal to minimise local tissue reaction and improve drug absorption. In dogs, administer by subcutaneous injection only never intravenously. In large animals, mild localised swelling at the injection site may occur and typically resolves within 7 to 14 days.

Storage Advice:

Store Lemasol-75 Injection below 25°C in a cool, dark, dry place. Protect strictly from direct sunlight Levamisole Hydrochloride is photosensitive and light exposure causes gradual potency degradation. Keep the vial cap tightly sealed between uses. Do not freeze. Keep out of reach of children. Do not use after the expiry date printed on the vial label and outer carton. Use aseptic technique for every dose drawn from the multi-dose vial to maintain sterility throughout the in-use period.

About the Brand:

Lemasol-75 is manufactured by a trusted Indian veterinary pharmaceutical company with a strong track record of delivering quality-assured, GMP-compliant veterinary injectable formulations to veterinarians, livestock farmers, and animal health professionals across India. With a formulation philosophy rooted in pharmaceutical precision, reliable active ingredient concentration accuracy, and accessible pricing that supports routine large animal herd deworming at the farm level, the manufacturer ensures that every vial of Lemasol-75 delivers the consistent potency and sterility that veterinarians and livestock managers depend upon for reliable therapeutic outcomes. Their commitment to accessible, quality-assured veterinary anthelmintic care aligns perfectly with Animeal's mission to provide registered veterinary professionals and livestock operators across India with reliable access to the full spectrum of veterinary pharmaceutical needs.

Disclaimer:

Lemasol-75 Injection is a prescription-only veterinary injectable anthelmintic that must be prescribed and administered exclusively by or under the direct supervision of a licensed veterinarian. It is not available for general retail sale or self-administration. Levamisole has a relatively narrow safety margin particularly in dogs where neurotoxicity including panting, trembling, and behavioural changes has been reported at doses slightly above the recommended therapeutic range. Do not use concurrently with Pyrantel both agents act via nicotinic acetylcholine receptor agonism and concurrent use significantly increases the risk of cholinergic toxicity. Do not use in lactating dairy animals without veterinary guidance. Do not use in severely debilitated, renally or hepatically impaired animals without veterinary assessment. Observe all meat and milk withholding periods strictly. Resistance of gastrointestinal nematodes to Levamisole is a growing concern in livestock regular faecal egg count reduction testing is recommended to monitor anthelmintic efficacy. Animeal facilitates enquiry and procurement for registered veterinary professionals only. Always refer to the current product prescribing information and your clinical judgement for complete prescribing, administration, and withholding period guidance.

Q: What is Levamisole's mechanism of action and why does it differ from Ivermectin and Albendazole?
Levamisole's primary nematocidal mechanism is nicotinic acetylcholine receptor agonism at the nematode neuromuscular junction causing irreversible spastic (tonic) paralysis of the worm's body musculature, followed by expulsion from the gut by intestinal peristalsis within hours. This is completely distinct from Ivermectin's mechanism which act on glutamate-gated chloride channels causing flaccid (not spastic) paralysis and from Albendazole's mechanism which inhibits tubulin polymerisation disrupting the nematode's cytoskeletal structure. Since resistance develops specifically to each individual mechanism of action, Levamisole's completely different target site means that nematode populations that have developed resistance to Ivermectin or Albendazole remain fully susceptible to Levamisole, making it the essential rotation and combination partner in managing multi-drug resistance in Indian livestock.
Q: What is the immunostimulant benefit of Levamisole and which animals benefit most?
Levamisole's immunostimulant effect involves restoration of depressed cell-mediated immune function specifically stimulation of T-lymphocyte maturation and proliferation, enhanced phagocytic activity of monocytes and macrophages, and increased antibody titre production. This effect is most pronounced and clinically meaningful in immunocompromised animals including livestock with heavy parasitic burdens, animals recovering from illness or nutritional deficiency, young animals with immature immune systems, and stressed animals following transport or environmental challenges. In these patients, the immunostimulant benefit of Levamisole translates into improved resistance to secondary infections including FMD and Rinderpest, faster clinical recovery, and improved overall disease resistance following anthelmintic treatment. In healthy, immunocompetent animals, the immunostimulant effect is less pronounced.
Q: Why must Levamisole never be combined with Pyrantel in dogs?
Levamisole and Pyrantel share the same pharmacological mechanism of action both are nicotinic acetylcholine receptor agonists at the nematode neuromuscular junction. However, because the nicotinic acetylcholine receptors targeted by both drugs are not completely nematode-specific, both agents also have some activity at mammalian nicotinic receptors at high plasma concentrations. When both drugs are administered concurrently, their combined cholinergic receptor stimulation produces additive and potentially synergistic toxicity in the treated animal, significantly increasing the risk of cholinergic adverse effects including excessive salivation, lacrimation, muscle tremors, ataxia, and in severe cases respiratory depression and collapse. This combination is therefore strictly contraindicated in all animal species.
Q: What are the most important safety precautions when using Lemasol-75 in dogs?
Levamisole has a significantly narrower safety margin in dogs than in large animals the therapeutic dose and the toxic dose are closer together, meaning dosing errors have more serious clinical consequences. Key precautions include: always weigh the dog accurately before calculating the dose rather than estimating; never exceed the maximum recommended dose of 10mg/kg in dogs; monitor closely for signs of neurotoxicity including panting, trembling, agitation, salivation, and behavioural changes in the first 2 hours post-injection; do not combine with Pyrantel; use with extreme caution or avoid entirely in Collies and related herding breeds that may carry the MDR1/ABCB1 gene mutation causing elevated central nervous system drug sensitivity; always administer subcutaneously never intravenously; and have atropine available for management of cholinergic toxicity if required.
Q: How can veterinary clinics and livestock operators procure Lemasol-75 Injection through Animeal?
Registered veterinary practitioners, veterinary clinics, animal hospitals, and authorised livestock farm operators can enquire about and procure Lemasol-75 Injection through Animeal's dedicated veterinary pharmaceutical enquiry channel. Please use the Enquire Now button on this product page or contact our veterinary pharma team directly via WhatsApp or phone with your valid veterinary prescription and practice or farm registration details. Our team will respond promptly with product availability, current pricing, pack size options, and delivery arrangements to your registered practice, clinic, or farm address anywhere across India.
LEMASOL-75 INJ
₹ 75.60
₹ 84.00  10% OFF

Frequently Asked Questions

What is Levamisole's mechanism of action and why does it differ from Ivermectin and Albendazole?

Levamisole's primary nematocidal mechanism is nicotinic acetylcholine receptor agonism at the nematode neuromuscular junction causing irreversible spastic (tonic) paralysis of the worm's body musculature, followed by expulsion from the gut by intestinal peristalsis within hours. This is completely distinct from Ivermectin's mechanism which act on glutamate-gated chloride channels causing flaccid (not spastic) paralysis and from Albendazole's mechanism which inhibits tubulin polymerisation disrupting the nematode's cytoskeletal structure. Since resistance develops specifically to each individual mechanism of action, Levamisole's completely different target site means that nematode populations that have developed resistance to Ivermectin or Albendazole remain fully susceptible to Levamisole, making it the essential rotation and combination partner in managing multi-drug resistance in Indian livestock.

What is the immunostimulant benefit of Levamisole and which animals benefit most?

Levamisole's immunostimulant effect involves restoration of depressed cell-mediated immune function specifically stimulation of T-lymphocyte maturation and proliferation, enhanced phagocytic activity of monocytes and macrophages, and increased antibody titre production. This effect is most pronounced and clinically meaningful in immunocompromised animals including livestock with heavy parasitic burdens, animals recovering from illness or nutritional deficiency, young animals with immature immune systems, and stressed animals following transport or environmental challenges. In these patients, the immunostimulant benefit of Levamisole translates into improved resistance to secondary infections including FMD and Rinderpest, faster clinical recovery, and improved overall disease resistance following anthelmintic treatment. In healthy, immunocompetent animals, the immunostimulant effect is less pronounced.

Why must Levamisole never be combined with Pyrantel in dogs?

Levamisole and Pyrantel share the same pharmacological mechanism of action both are nicotinic acetylcholine receptor agonists at the nematode neuromuscular junction. However, because the nicotinic acetylcholine receptors targeted by both drugs are not completely nematode-specific, both agents also have some activity at mammalian nicotinic receptors at high plasma concentrations. When both drugs are administered concurrently, their combined cholinergic receptor stimulation produces additive and potentially synergistic toxicity in the treated animal, significantly increasing the risk of cholinergic adverse effects including excessive salivation, lacrimation, muscle tremors, ataxia, and in severe cases respiratory depression and collapse. This combination is therefore strictly contraindicated in all animal species.

What are the most important safety precautions when using Lemasol-75 in dogs?

Levamisole has a significantly narrower safety margin in dogs than in large animals the therapeutic dose and the toxic dose are closer together, meaning dosing errors have more serious clinical consequences. Key precautions include: always weigh the dog accurately before calculating the dose rather than estimating; never exceed the maximum recommended dose of 10mg/kg in dogs; monitor closely for signs of neurotoxicity including panting, trembling, agitation, salivation, and behavioural changes in the first 2 hours post-injection; do not combine with Pyrantel; use with extreme caution or avoid entirely in Collies and related herding breeds that may carry the MDR1/ABCB1 gene mutation causing elevated central nervous system drug sensitivity; always administer subcutaneously never intravenously; and have atropine available for management of cholinergic toxicity if required.

How can veterinary clinics and livestock operators procure Lemasol-75 Injection through Animeal?

Registered veterinary practitioners, veterinary clinics, animal hospitals, and authorised livestock farm operators can enquire about and procure Lemasol-75 Injection through Animeal's dedicated veterinary pharmaceutical enquiry channel. Please use the Enquire Now button on this product page or contact our veterinary pharma team directly via WhatsApp or phone with your valid veterinary prescription and practice or farm registration details. Our team will respond promptly with product availability, current pricing, pack size options, and delivery arrangements to your registered practice, clinic, or farm address anywhere across India.
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