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LEMASOL-75 INJ

LEMASOL-75 INJ

By ZENEX AH

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Expires on or after: Feb, 2028

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About Lemasol-75 Injection

Some medicines work best as an injection, given by a vet when a fast or reliable dose is needed.

Lemasol-75 Injection is an injection from Zenex that contains levamisole. Levamisole is a dewormer.

Vets commonly use it for roundworms and lungworms in cattle, sheep and goats. Your vet will confirm it suits your animal and set the dose and how long to give it.

Prescription Notice

This is a prescription veterinary product. Animeal dispenses it only against a valid prescription from a registered veterinarian. You can upload the prescription at checkout or send it on WhatsApp to +91 90041 57093.

Composition

Active ingredients listed for this product. The exact strength is printed on the pack.

Ingredient What it does
Levamisole Kills roundworms and lungworms.

Features and Benefits

  • Injection. Works quickly and gives a reliable dose when tablets are not practical.
  • Vet-guided. Your vet sets the dose and length of treatment for your animal.

How It Works

  • Levamisole. It paralyses worms so they are passed out.

How to Use

  • Given by a vet. Injections should be given by a vet, or by someone your vet has trained, using a sterile needle and syringe each time.
  • Dose. Your vet works out the dose from your animal's weight and condition, and decides how many injections are needed.
  • Storage. Store in a cool, dry place away from direct sunlight, unless the pack gives other storage directions. Keep out of reach of children.

Safety and Precautions

  • Stick to the dose for the animal's weight. Levamisole has a narrow safety margin.
  • Follow the milk and meat withdrawal period printed on the pack before milk or meat from treated animals is used for food.
  • Tell your vet about any other medicines your animal takes, and if your animal is pregnant, nursing or has liver or kidney problems.

Frequently Asked Questions

Do I need a prescription for Lemasol-75 Injection?

Yes. Lemasol-75 Injection is a prescription medicine. Animeal needs a valid prescription from a registered vet before it can be dispatched. You can upload it at checkout or send it on WhatsApp to +91 90041 57093.

What is Lemasol-75 Injection used for?

Lemasol-75 Injection contains levamisole. Vets use it for roundworms and lungworms in cattle, sheep and goats. Your vet decides whether it is right for your animal and for how long.

Can I give Lemasol-75 Injection at home?

Only if your vet has prescribed it and shown you how to inject safely. Most injections are given at the clinic.

Also in: Injectables for Farm Animals · All Farm Animal Products

Product Information

Detail Information
Brand Zenex
Active ingredients Levamisole
Form Injection
Pack size 30ml
Suitable for Cattle, buffaloes, sheep and goats
Prescription Required
Sold by Goodman Vetcare Pvt. Ltd. (Animeal), Warehouse No - 501 5th floor, Bharat industrial estate, Tokershi Jivraj Rd, Sewree West, Sindhu Nagar, Sewri, Mumbai, Maharashtra 400015

This product requires a valid prescription from a registered veterinarian. Animeal shares this information for educational purposes only. Always consult your vet before use.

Company Name & AddressZenex Animal Health India Pvt. Ltd., 9th Floor, N G Tower, Satellite Cross Roads, Sarkhej-Gandhinagar Highway, Ahmedabad – 380015, Gujarat

Broad Gastrointestinal Nematode Spectrum Cattle, Buffaloes & Sheep: Lemasol-75 provides clinically reliable coverage against all major gastrointestinal nematode species affecting Indian cattle, buffaloes, and sheep including Haemonchus contortus (Barber's Pole Worm the most economically important), Ostertagia spp., Trichostrongylus spp., Cooperia spp., Nematodirus spp., Bunostomum spp. (hookworm), Oesophagostomum spp. (nodular worm), Chabertia spp., and Neoascaris vitulorum in young calves

Pulmonary Nematode (Lungworm) Control Dictyocaulus spp. one of Levamisole's most clinically important advantages over benzimidazoles in cattle and sheep practice reliable efficacy against Dictyocaulus viviparus (bovine lungworm) and Dictyocaulus filaria (ovine lungworm) the causative agents of parasitic bronchitis (husk, hoose) that cause severe coughing, respiratory distress, and significant production losses and mortality in young cattle and sheep

Comprehensive Swine Nematode Coverage: effective against the major gastrointestinal and pulmonary nematode species in Indian pigs including Ascaris suum, Oesophagostomum spp., Strongyloides ransomi, Stephanurus dentatus (kidney worm), and the lung nematodes Metastrongylus spp. (swine lungworm)

Companion Animal Endoparasiticide Applications: under veterinary prescription and with careful weight-based dosing, Levamisole is used in dogs for the treatment of roundworm (Toxocara canis, Toxascaris leonina) and hookworm (Ancylostoma caninum, Uncinaria stenocephala) infestations, and historically as a microfilaricide in the management of Dirofilaria immitis (heartworm) microfilariae a use requiring specialist veterinary supervision given the narrow safety margin in dogs

Unique Immunostimulant Benefit for Disease Resistance: the restoration of depressed cell-mediated immunity and enhanced antibody titre production that Levamisole provides to treated animals represents a meaningful clinical benefit beyond simple parasite elimination actively improving livestock resistance to major infectious diseases including FMD, Rinderpest, and secondary bacterial pneumonia that commonly complicate or follow significant parasitic infestations

Critical Anthelmintic Rotation Partner for Resistance Management: the imidazothiazole mechanism of action of Levamisole is completely distinct from benzimidazoles, macrocyclic lactones, and tetrahydropyrimidines making Lemasol-75 the most important strategic rotation anthelmintic for Indian livestock veterinarians and farmers implementing integrated parasite management programmes designed to delay, detect, and manage anthelmintic resistance in their herds

Rapid Onset Injectable Delivery for Maximum Bioavailability: the injectable delivery route ensures complete, predictable systemic bioavailability unaffected by variable gastrointestinal absorption, poor compliance with oral drenching, or the significant reduction in efficacy caused by feeding immediately before oral Levamisole administration making the injectable formulation the preferred choice for guaranteed therapeutic blood levels in field conditions

Convenient 30ml Multi-Dose Vial for Field & Farm Use: the 30ml vial provides sufficient volume for multiple large animal treatments at a single farm visit, reducing the number of vials required for routine herd deworming and minimising pharmaceutical waste in field practice

How to Use:

For subcutaneous (S/C) injection in large animals administered by or under the direct supervision of a licensed veterinarian only. In large animals, the preferred injection site is the side of the neck or pre-scapular region. Draw the required dose into a clean, sterile syringe using aseptic technique. Administer by slow subcutaneous injection, distributing large-volume doses across multiple injection sites in the same animal to minimise local tissue reaction and improve drug absorption. In dogs, administer by subcutaneous injection only never intravenously. In large animals, mild localised swelling at the injection site may occur and typically resolves within 7 to 14 days.

Storage Advice:

Store Lemasol-75 Injection below 25°C in a cool, dark, dry place. Protect strictly from direct sunlight Levamisole Hydrochloride is photosensitive and light exposure causes gradual potency degradation. Keep the vial cap tightly sealed between uses. Do not freeze. Keep out of reach of children. Do not use after the expiry date printed on the vial label and outer carton. Use aseptic technique for every dose drawn from the multi-dose vial to maintain sterility throughout the in-use period.

About the Brand:

Lemasol-75 is manufactured by a trusted Indian veterinary pharmaceutical company with a strong track record of delivering quality-assured, GMP-compliant veterinary injectable formulations to veterinarians, livestock farmers, and animal health professionals across India. With a formulation philosophy rooted in pharmaceutical precision, reliable active ingredient concentration accuracy, and accessible pricing that supports routine large animal herd deworming at the farm level, the manufacturer ensures that every vial of Lemasol-75 delivers the consistent potency and sterility that veterinarians and livestock managers depend upon for reliable therapeutic outcomes. Their commitment to accessible, quality-assured veterinary anthelmintic care aligns perfectly with Animeal's mission to provide registered veterinary professionals and livestock operators across India with reliable access to the full spectrum of veterinary pharmaceutical needs.

Disclaimer:

Lemasol-75 Injection is a prescription-only veterinary injectable anthelmintic that must be prescribed and administered exclusively by or under the direct supervision of a licensed veterinarian. It is not available for general retail sale or self-administration. Levamisole has a relatively narrow safety margin particularly in dogs where neurotoxicity including panting, trembling, and behavioural changes has been reported at doses slightly above the recommended therapeutic range. Do not use concurrently with Pyrantel both agents act via nicotinic acetylcholine receptor agonism and concurrent use significantly increases the risk of cholinergic toxicity. Do not use in lactating dairy animals without veterinary guidance. Do not use in severely debilitated, renally or hepatically impaired animals without veterinary assessment. Observe all meat and milk withholding periods strictly. Resistance of gastrointestinal nematodes to Levamisole is a growing concern in livestock regular faecal egg count reduction testing is recommended to monitor anthelmintic efficacy. Animeal facilitates enquiry and procurement for registered veterinary professionals only. Always refer to the current product prescribing information and your clinical judgement for complete prescribing, administration, and withholding period guidance.

Q: What is Levamisole's mechanism of action and why does it differ from Ivermectin and Albendazole?
Levamisole's primary nematocidal mechanism is nicotinic acetylcholine receptor agonism at the nematode neuromuscular junction causing irreversible spastic (tonic) paralysis of the worm's body musculature, followed by expulsion from the gut by intestinal peristalsis within hours. This is completely distinct from Ivermectin's mechanism which act on glutamate-gated chloride channels causing flaccid (not spastic) paralysis and from Albendazole's mechanism which inhibits tubulin polymerisation disrupting the nematode's cytoskeletal structure. Since resistance develops specifically to each individual mechanism of action, Levamisole's completely different target site means that nematode populations that have developed resistance to Ivermectin or Albendazole remain fully susceptible to Levamisole, making it the essential rotation and combination partner in managing multi-drug resistance in Indian livestock.
Q: What is the immunostimulant benefit of Levamisole and which animals benefit most?
Levamisole's immunostimulant effect involves restoration of depressed cell-mediated immune function specifically stimulation of T-lymphocyte maturation and proliferation, enhanced phagocytic activity of monocytes and macrophages, and increased antibody titre production. This effect is most pronounced and clinically meaningful in immunocompromised animals including livestock with heavy parasitic burdens, animals recovering from illness or nutritional deficiency, young animals with immature immune systems, and stressed animals following transport or environmental challenges. In these patients, the immunostimulant benefit of Levamisole translates into improved resistance to secondary infections including FMD and Rinderpest, faster clinical recovery, and improved overall disease resistance following anthelmintic treatment. In healthy, immunocompetent animals, the immunostimulant effect is less pronounced.
Q: Why must Levamisole never be combined with Pyrantel in dogs?
Levamisole and Pyrantel share the same pharmacological mechanism of action both are nicotinic acetylcholine receptor agonists at the nematode neuromuscular junction. However, because the nicotinic acetylcholine receptors targeted by both drugs are not completely nematode-specific, both agents also have some activity at mammalian nicotinic receptors at high plasma concentrations. When both drugs are administered concurrently, their combined cholinergic receptor stimulation produces additive and potentially synergistic toxicity in the treated animal, significantly increasing the risk of cholinergic adverse effects including excessive salivation, lacrimation, muscle tremors, ataxia, and in severe cases respiratory depression and collapse. This combination is therefore strictly contraindicated in all animal species.
Q: What are the most important safety precautions when using Lemasol-75 in dogs?
Levamisole has a significantly narrower safety margin in dogs than in large animals the therapeutic dose and the toxic dose are closer together, meaning dosing errors have more serious clinical consequences. Key precautions include: always weigh the dog accurately before calculating the dose rather than estimating; never exceed the maximum recommended dose of 10mg/kg in dogs; monitor closely for signs of neurotoxicity including panting, trembling, agitation, salivation, and behavioural changes in the first 2 hours post-injection; do not combine with Pyrantel; use with extreme caution or avoid entirely in Collies and related herding breeds that may carry the MDR1/ABCB1 gene mutation causing elevated central nervous system drug sensitivity; always administer subcutaneously never intravenously; and have atropine available for management of cholinergic toxicity if required.
Q: How can veterinary clinics and livestock operators procure Lemasol-75 Injection through Animeal?
Registered veterinary practitioners, veterinary clinics, animal hospitals, and authorised livestock farm operators can enquire about and procure Lemasol-75 Injection through Animeal's dedicated veterinary pharmaceutical enquiry channel. Please use the Enquire Now button on this product page or contact our veterinary pharma team directly via WhatsApp or phone with your valid veterinary prescription and practice or farm registration details. Our team will respond promptly with product availability, current pricing, pack size options, and delivery arrangements to your registered practice, clinic, or farm address anywhere across India.
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INJECTABLE

LEMASOL-75 INJ

By ZENEX AH
WhatsApp us to book your order!

In Stock

Expires on or after: Feb, 2028
Size

Prescription Required question

Check Availability

About Lemasol-75 Injection

Some medicines work best as an injection, given by a vet when a fast or reliable dose is needed.

Lemasol-75 Injection is an injection from Zenex that contains levamisole. Levamisole is a dewormer.

Vets commonly use it for roundworms and lungworms in cattle, sheep and goats. Your vet will confirm it suits your animal and set the dose and how long to give it.

Prescription Notice

This is a prescription veterinary product. Animeal dispenses it only against a valid prescription from a registered veterinarian. You can upload the prescription at checkout or send it on WhatsApp to +91 90041 57093.

Composition

Active ingredients listed for this product. The exact strength is printed on the pack.

Ingredient What it does
Levamisole Kills roundworms and lungworms.

Features and Benefits

  • Injection. Works quickly and gives a reliable dose when tablets are not practical.
  • Vet-guided. Your vet sets the dose and length of treatment for your animal.

How It Works

  • Levamisole. It paralyses worms so they are passed out.

How to Use

  • Given by a vet. Injections should be given by a vet, or by someone your vet has trained, using a sterile needle and syringe each time.
  • Dose. Your vet works out the dose from your animal's weight and condition, and decides how many injections are needed.
  • Storage. Store in a cool, dry place away from direct sunlight, unless the pack gives other storage directions. Keep out of reach of children.

Safety and Precautions

  • Stick to the dose for the animal's weight. Levamisole has a narrow safety margin.
  • Follow the milk and meat withdrawal period printed on the pack before milk or meat from treated animals is used for food.
  • Tell your vet about any other medicines your animal takes, and if your animal is pregnant, nursing or has liver or kidney problems.

Frequently Asked Questions

Do I need a prescription for Lemasol-75 Injection?

Yes. Lemasol-75 Injection is a prescription medicine. Animeal needs a valid prescription from a registered vet before it can be dispatched. You can upload it at checkout or send it on WhatsApp to +91 90041 57093.

What is Lemasol-75 Injection used for?

Lemasol-75 Injection contains levamisole. Vets use it for roundworms and lungworms in cattle, sheep and goats. Your vet decides whether it is right for your animal and for how long.

Can I give Lemasol-75 Injection at home?

Only if your vet has prescribed it and shown you how to inject safely. Most injections are given at the clinic.

Also in: Injectables for Farm Animals · All Farm Animal Products

Product Information

Detail Information
Brand Zenex
Active ingredients Levamisole
Form Injection
Pack size 30ml
Suitable for Cattle, buffaloes, sheep and goats
Prescription Required
Sold by Goodman Vetcare Pvt. Ltd. (Animeal), Warehouse No - 501 5th floor, Bharat industrial estate, Tokershi Jivraj Rd, Sewree West, Sindhu Nagar, Sewri, Mumbai, Maharashtra 400015

This product requires a valid prescription from a registered veterinarian. Animeal shares this information for educational purposes only. Always consult your vet before use.

Company Name & AddressZenex Animal Health India Pvt. Ltd., 9th Floor, N G Tower, Satellite Cross Roads, Sarkhej-Gandhinagar Highway, Ahmedabad – 380015, Gujarat

Broad Gastrointestinal Nematode Spectrum Cattle, Buffaloes & Sheep: Lemasol-75 provides clinically reliable coverage against all major gastrointestinal nematode species affecting Indian cattle, buffaloes, and sheep including Haemonchus contortus (Barber's Pole Worm the most economically important), Ostertagia spp., Trichostrongylus spp., Cooperia spp., Nematodirus spp., Bunostomum spp. (hookworm), Oesophagostomum spp. (nodular worm), Chabertia spp., and Neoascaris vitulorum in young calves

Pulmonary Nematode (Lungworm) Control Dictyocaulus spp. one of Levamisole's most clinically important advantages over benzimidazoles in cattle and sheep practice reliable efficacy against Dictyocaulus viviparus (bovine lungworm) and Dictyocaulus filaria (ovine lungworm) the causative agents of parasitic bronchitis (husk, hoose) that cause severe coughing, respiratory distress, and significant production losses and mortality in young cattle and sheep

Comprehensive Swine Nematode Coverage: effective against the major gastrointestinal and pulmonary nematode species in Indian pigs including Ascaris suum, Oesophagostomum spp., Strongyloides ransomi, Stephanurus dentatus (kidney worm), and the lung nematodes Metastrongylus spp. (swine lungworm)

Companion Animal Endoparasiticide Applications: under veterinary prescription and with careful weight-based dosing, Levamisole is used in dogs for the treatment of roundworm (Toxocara canis, Toxascaris leonina) and hookworm (Ancylostoma caninum, Uncinaria stenocephala) infestations, and historically as a microfilaricide in the management of Dirofilaria immitis (heartworm) microfilariae a use requiring specialist veterinary supervision given the narrow safety margin in dogs

Unique Immunostimulant Benefit for Disease Resistance: the restoration of depressed cell-mediated immunity and enhanced antibody titre production that Levamisole provides to treated animals represents a meaningful clinical benefit beyond simple parasite elimination actively improving livestock resistance to major infectious diseases including FMD, Rinderpest, and secondary bacterial pneumonia that commonly complicate or follow significant parasitic infestations

Critical Anthelmintic Rotation Partner for Resistance Management: the imidazothiazole mechanism of action of Levamisole is completely distinct from benzimidazoles, macrocyclic lactones, and tetrahydropyrimidines making Lemasol-75 the most important strategic rotation anthelmintic for Indian livestock veterinarians and farmers implementing integrated parasite management programmes designed to delay, detect, and manage anthelmintic resistance in their herds

Rapid Onset Injectable Delivery for Maximum Bioavailability: the injectable delivery route ensures complete, predictable systemic bioavailability unaffected by variable gastrointestinal absorption, poor compliance with oral drenching, or the significant reduction in efficacy caused by feeding immediately before oral Levamisole administration making the injectable formulation the preferred choice for guaranteed therapeutic blood levels in field conditions

Convenient 30ml Multi-Dose Vial for Field & Farm Use: the 30ml vial provides sufficient volume for multiple large animal treatments at a single farm visit, reducing the number of vials required for routine herd deworming and minimising pharmaceutical waste in field practice

How to Use:

For subcutaneous (S/C) injection in large animals administered by or under the direct supervision of a licensed veterinarian only. In large animals, the preferred injection site is the side of the neck or pre-scapular region. Draw the required dose into a clean, sterile syringe using aseptic technique. Administer by slow subcutaneous injection, distributing large-volume doses across multiple injection sites in the same animal to minimise local tissue reaction and improve drug absorption. In dogs, administer by subcutaneous injection only never intravenously. In large animals, mild localised swelling at the injection site may occur and typically resolves within 7 to 14 days.

Storage Advice:

Store Lemasol-75 Injection below 25°C in a cool, dark, dry place. Protect strictly from direct sunlight Levamisole Hydrochloride is photosensitive and light exposure causes gradual potency degradation. Keep the vial cap tightly sealed between uses. Do not freeze. Keep out of reach of children. Do not use after the expiry date printed on the vial label and outer carton. Use aseptic technique for every dose drawn from the multi-dose vial to maintain sterility throughout the in-use period.

About the Brand:

Lemasol-75 is manufactured by a trusted Indian veterinary pharmaceutical company with a strong track record of delivering quality-assured, GMP-compliant veterinary injectable formulations to veterinarians, livestock farmers, and animal health professionals across India. With a formulation philosophy rooted in pharmaceutical precision, reliable active ingredient concentration accuracy, and accessible pricing that supports routine large animal herd deworming at the farm level, the manufacturer ensures that every vial of Lemasol-75 delivers the consistent potency and sterility that veterinarians and livestock managers depend upon for reliable therapeutic outcomes. Their commitment to accessible, quality-assured veterinary anthelmintic care aligns perfectly with Animeal's mission to provide registered veterinary professionals and livestock operators across India with reliable access to the full spectrum of veterinary pharmaceutical needs.

Disclaimer:

Lemasol-75 Injection is a prescription-only veterinary injectable anthelmintic that must be prescribed and administered exclusively by or under the direct supervision of a licensed veterinarian. It is not available for general retail sale or self-administration. Levamisole has a relatively narrow safety margin particularly in dogs where neurotoxicity including panting, trembling, and behavioural changes has been reported at doses slightly above the recommended therapeutic range. Do not use concurrently with Pyrantel both agents act via nicotinic acetylcholine receptor agonism and concurrent use significantly increases the risk of cholinergic toxicity. Do not use in lactating dairy animals without veterinary guidance. Do not use in severely debilitated, renally or hepatically impaired animals without veterinary assessment. Observe all meat and milk withholding periods strictly. Resistance of gastrointestinal nematodes to Levamisole is a growing concern in livestock regular faecal egg count reduction testing is recommended to monitor anthelmintic efficacy. Animeal facilitates enquiry and procurement for registered veterinary professionals only. Always refer to the current product prescribing information and your clinical judgement for complete prescribing, administration, and withholding period guidance.

Q: What is Levamisole's mechanism of action and why does it differ from Ivermectin and Albendazole?
Levamisole's primary nematocidal mechanism is nicotinic acetylcholine receptor agonism at the nematode neuromuscular junction causing irreversible spastic (tonic) paralysis of the worm's body musculature, followed by expulsion from the gut by intestinal peristalsis within hours. This is completely distinct from Ivermectin's mechanism which act on glutamate-gated chloride channels causing flaccid (not spastic) paralysis and from Albendazole's mechanism which inhibits tubulin polymerisation disrupting the nematode's cytoskeletal structure. Since resistance develops specifically to each individual mechanism of action, Levamisole's completely different target site means that nematode populations that have developed resistance to Ivermectin or Albendazole remain fully susceptible to Levamisole, making it the essential rotation and combination partner in managing multi-drug resistance in Indian livestock.
Q: What is the immunostimulant benefit of Levamisole and which animals benefit most?
Levamisole's immunostimulant effect involves restoration of depressed cell-mediated immune function specifically stimulation of T-lymphocyte maturation and proliferation, enhanced phagocytic activity of monocytes and macrophages, and increased antibody titre production. This effect is most pronounced and clinically meaningful in immunocompromised animals including livestock with heavy parasitic burdens, animals recovering from illness or nutritional deficiency, young animals with immature immune systems, and stressed animals following transport or environmental challenges. In these patients, the immunostimulant benefit of Levamisole translates into improved resistance to secondary infections including FMD and Rinderpest, faster clinical recovery, and improved overall disease resistance following anthelmintic treatment. In healthy, immunocompetent animals, the immunostimulant effect is less pronounced.
Q: Why must Levamisole never be combined with Pyrantel in dogs?
Levamisole and Pyrantel share the same pharmacological mechanism of action both are nicotinic acetylcholine receptor agonists at the nematode neuromuscular junction. However, because the nicotinic acetylcholine receptors targeted by both drugs are not completely nematode-specific, both agents also have some activity at mammalian nicotinic receptors at high plasma concentrations. When both drugs are administered concurrently, their combined cholinergic receptor stimulation produces additive and potentially synergistic toxicity in the treated animal, significantly increasing the risk of cholinergic adverse effects including excessive salivation, lacrimation, muscle tremors, ataxia, and in severe cases respiratory depression and collapse. This combination is therefore strictly contraindicated in all animal species.
Q: What are the most important safety precautions when using Lemasol-75 in dogs?
Levamisole has a significantly narrower safety margin in dogs than in large animals the therapeutic dose and the toxic dose are closer together, meaning dosing errors have more serious clinical consequences. Key precautions include: always weigh the dog accurately before calculating the dose rather than estimating; never exceed the maximum recommended dose of 10mg/kg in dogs; monitor closely for signs of neurotoxicity including panting, trembling, agitation, salivation, and behavioural changes in the first 2 hours post-injection; do not combine with Pyrantel; use with extreme caution or avoid entirely in Collies and related herding breeds that may carry the MDR1/ABCB1 gene mutation causing elevated central nervous system drug sensitivity; always administer subcutaneously never intravenously; and have atropine available for management of cholinergic toxicity if required.
Q: How can veterinary clinics and livestock operators procure Lemasol-75 Injection through Animeal?
Registered veterinary practitioners, veterinary clinics, animal hospitals, and authorised livestock farm operators can enquire about and procure Lemasol-75 Injection through Animeal's dedicated veterinary pharmaceutical enquiry channel. Please use the Enquire Now button on this product page or contact our veterinary pharma team directly via WhatsApp or phone with your valid veterinary prescription and practice or farm registration details. Our team will respond promptly with product availability, current pricing, pack size options, and delivery arrangements to your registered practice, clinic, or farm address anywhere across India.

Frequently Asked Questions

What is Levamisole's mechanism of action and why does it differ from Ivermectin and Albendazole?

Levamisole's primary nematocidal mechanism is nicotinic acetylcholine receptor agonism at the nematode neuromuscular junction causing irreversible spastic (tonic) paralysis of the worm's body musculature, followed by expulsion from the gut by intestinal peristalsis within hours. This is completely distinct from Ivermectin's mechanism which act on glutamate-gated chloride channels causing flaccid (not spastic) paralysis and from Albendazole's mechanism which inhibits tubulin polymerisation disrupting the nematode's cytoskeletal structure. Since resistance develops specifically to each individual mechanism of action, Levamisole's completely different target site means that nematode populations that have developed resistance to Ivermectin or Albendazole remain fully susceptible to Levamisole, making it the essential rotation and combination partner in managing multi-drug resistance in Indian livestock.

What is the immunostimulant benefit of Levamisole and which animals benefit most?

Levamisole's immunostimulant effect involves restoration of depressed cell-mediated immune function specifically stimulation of T-lymphocyte maturation and proliferation, enhanced phagocytic activity of monocytes and macrophages, and increased antibody titre production. This effect is most pronounced and clinically meaningful in immunocompromised animals including livestock with heavy parasitic burdens, animals recovering from illness or nutritional deficiency, young animals with immature immune systems, and stressed animals following transport or environmental challenges. In these patients, the immunostimulant benefit of Levamisole translates into improved resistance to secondary infections including FMD and Rinderpest, faster clinical recovery, and improved overall disease resistance following anthelmintic treatment. In healthy, immunocompetent animals, the immunostimulant effect is less pronounced.

Why must Levamisole never be combined with Pyrantel in dogs?

Levamisole and Pyrantel share the same pharmacological mechanism of action both are nicotinic acetylcholine receptor agonists at the nematode neuromuscular junction. However, because the nicotinic acetylcholine receptors targeted by both drugs are not completely nematode-specific, both agents also have some activity at mammalian nicotinic receptors at high plasma concentrations. When both drugs are administered concurrently, their combined cholinergic receptor stimulation produces additive and potentially synergistic toxicity in the treated animal, significantly increasing the risk of cholinergic adverse effects including excessive salivation, lacrimation, muscle tremors, ataxia, and in severe cases respiratory depression and collapse. This combination is therefore strictly contraindicated in all animal species.

What are the most important safety precautions when using Lemasol-75 in dogs?

Levamisole has a significantly narrower safety margin in dogs than in large animals the therapeutic dose and the toxic dose are closer together, meaning dosing errors have more serious clinical consequences. Key precautions include: always weigh the dog accurately before calculating the dose rather than estimating; never exceed the maximum recommended dose of 10mg/kg in dogs; monitor closely for signs of neurotoxicity including panting, trembling, agitation, salivation, and behavioural changes in the first 2 hours post-injection; do not combine with Pyrantel; use with extreme caution or avoid entirely in Collies and related herding breeds that may carry the MDR1/ABCB1 gene mutation causing elevated central nervous system drug sensitivity; always administer subcutaneously never intravenously; and have atropine available for management of cholinergic toxicity if required.

How can veterinary clinics and livestock operators procure Lemasol-75 Injection through Animeal?

Registered veterinary practitioners, veterinary clinics, animal hospitals, and authorised livestock farm operators can enquire about and procure Lemasol-75 Injection through Animeal's dedicated veterinary pharmaceutical enquiry channel. Please use the Enquire Now button on this product page or contact our veterinary pharma team directly via WhatsApp or phone with your valid veterinary prescription and practice or farm registration details. Our team will respond promptly with product availability, current pricing, pack size options, and delivery arrangements to your registered practice, clinic, or farm address anywhere across India.