ANTI BIOTIC

MASTIWOK SYRINGE

By VETOQUINAL

₹ 257.81

₹ 257.81 M.R.P:

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Pack - 10mL

Expires on or after: Feb, 2027

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About Product

Mastiwok is a standout product in our VETERINARY ANTIBIOTIC category. Manufactured by Vetoquinol S.A. one of France's most prestigious and globally respected veterinary pharmaceutical companies with over 85 years of veterinary pharmaceutical excellence Mastiwok delivers Cefoperazone Sodium 250mg in a convenient, pre-filled, ready-to-use intramammary syringe that ensures precise, sterile, and clinically effective antibiotic delivery directly into the affected udder quarter. With its broad-spectrum bactericidal activity against the most common mastitis-causing pathogens in Indian dairy cattle, its excellent penetration into inflamed mammary gland tissue, and its convenient pre-filled syringe format that minimises contamination risk during administration, Mastiwok has established itself as a trusted first-line choice among Indian dairy veterinarians and progressive dairy farmers for rapid, reliable mastitis resolution. With Mastiwok, you can trust that you are offering your dairy animals the very best in evidence-based, pharmaceutical-grade mastitis management.

Composition:

Each Mastiwok pre-filled intramammary syringe contains a precisely formulated pharmaceutical composition for direct intramammary delivery:

Cefoperazone Sodium 250mg (Active Ingredient) a third-generation, broad-spectrum cephalosporin antibiotic that exerts its bactericidal activity by irreversibly binding to penicillin-binding proteins (PBPs) in the bacterial cell wall, thereby inhibiting the final transpeptidation step of peptidoglycan synthesis the structural polymer essential for maintaining bacterial cell wall integrity. This binding causes progressive weakening and eventual lysis of the bacterial cell wall, resulting in rapid bacterial cell death. Cefoperazone's third-generation cephalosporin classification confers significantly enhanced stability against beta-lactamase enzymatic degradation compared to first and second-generation cephalosporins maintaining bactericidal efficacy against many beta-lactamase-producing bacterial strains that would inactivate earlier-generation agents
Dispersible Mineral Oil Base: a pharmaceutical-grade, viscous mineral oil vehicle that serves as the intramammary delivery base, ensuring the active ingredient is uniformly suspended and retained within the mammary gland cistern for an extended duration after infusion maximising the tissue contact time and local drug concentration required for complete bactericidal efficacy against all mastitis pathogens present in the affected quarter
Aluminium Monostearate (Gelling Agent): a pharmaceutical excipient that contributes to the characteristic semi-viscous, gel-like consistency of the intramammary suspension ensuring optimal retention of the antibiotic within the udder cistern and teat canal after infusion, preventing premature drainage and maintaining therapeutic drug concentrations at the site of infection throughout the treatment period
Lecithin (Emulsifier & Spreading Agent): a naturally derived phospholipid emulsifier that facilitates the uniform distribution and spreading of the antibiotic suspension throughout the mammary gland cistern and ductular system, ensuring comprehensive coverage of all infected tissue surfaces within the treated quarter

Features and Benefits

Broad-Spectrum Bactericidal Coverage for All Ma...

Broad-Spectrum Bactericidal Coverage for All Major Mastitis Pathogens: Cefoperazone Sodium's third-generation cephalosporin spectrum provides effective bactericidal activity against the complete range of gram-positive and gram-negative mastitis-causing organisms most commonly encountered in Indian dairy cattle including Staphylococcus aureus, Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus uberis, Escherichia coli, Klebsiella spp., Enterobacter spp., and Pseudomonas aeruginosa ensuring reliable therapeutic coverage even when the specific causative organism has not yet been identified by culture and sensitivity testing

Enhanced Beta-Lactamase Stability for Resistant Strains: the third-generation cephalosporin classification of Cefoperazone confers significantly superior stability against the beta-lactamase enzymes produced by many mastitis pathogens particularly beta-lactamase-producing Staphylococcus aureus strains compared to first and second-generation cephalosporins and penicillin-class antibiotics, ensuring maintained bactericidal efficacy in cases involving resistant or partially resistant organisms

Excellent Penetration into Inflamed Mammary Tissue: the physicochemical properties of Cefoperazone Sodium and the mineral oil base formulation ensure superior penetration and distribution of the active ingredient throughout inflamed mammary gland tissue reaching therapeutic bactericidal concentrations in the parenchymal tissue and ductular system of affected quarters, not just the cistern providing far more complete treatment of deep-seated parenchymal infections compared to water-based formulations

Extended Local Drug Retention for Sustained Therapeutic Action: the viscous mineral oil base and aluminium monostearate gelling system ensure prolonged retention of the antibiotic suspension within the mammary gland cistern after infusion maintaining local therapeutic drug concentrations at the site of infection throughout the complete treatment interval between infusions and supporting complete bacteriological cure rather than merely temporary clinical resolution

Treatment of Both Clinical & Sub-Clinical Mastitis: Mastiwok is indicated for the effective treatment of both clinically apparent mastitis (with visible changes in milk appearance, udder swelling, heat, and pain) and sub-clinical mastitis (detectable by elevated somatic cell count or California Mastitis Test positivity without visible clinical signs) making it a comprehensive mastitis management tool for both acute treatment and herd-level sub-clinical control programs

Convenient Pre-Filled Sterile Syringe Format: the ready-to-use, pre-filled syringe format eliminates the preparation errors, dose measurement inaccuracies, and contamination risks associated with multi-dose vials and manual syringe filling ensuring precise, consistent, and sterile intramammary delivery with every treatment, significantly reducing the risk of iatrogenic teat canal contamination and treatment failure

Rapid Clinical Response for Swift Animal Welfare Improvement: the bactericidal mechanism and excellent mammary tissue penetration of Cefoperazone Sodium support rapid clinical improvement including resolution of udder inflammation, return of normal milk appearance, and reduction of animal discomfort typically within the first 24 to 48 hours of initiating treatment, supporting both animal welfare and early restoration of milk production

Usage and Applications

How to Use:For administration by or under the d...

How to Use:

For administration by or under the direct supervision of a licensed veterinarian only. Immediately before use, thoroughly strip and discard all milk from the affected quarter. Clean and dry the teat thoroughly. Disinfect the teat end with a spirit swab and allow to dry completely. Remove the cap from the pre-filled syringe and gently insert the syringe nozzle into the teat canal without forcing. Infuse the entire contents of the syringe slowly and completely into the teat cistern. After infusion, gently massage the teat and lower udder to distribute the suspension upward into the gland cistern. Apply a post-dipping teat disinfectant to the teat end after each infusion. Repeat the treatment at the next milking interval as directed by your veterinarian.

Storage Advice:

Store Mastiwok Intramammary Infusion below 25°C in a cool, dry place away from direct sunlight and heat. Do not freeze. Keep in original packaging until point of use. Keep out of reach of children. Do not use after the expiry date printed on the syringe label and outer packaging. Use immediately once the syringe cap has been removed do not store opened, partially used syringes.

About the Brand:

Vetoquinol S.A. is one of the world's most prestigious and respected veterinary pharmaceutical companies founded in France in 1933 and operating across more than 30 countries with a dedicated global presence spanning companion animal, production animal, and equine veterinary medicine. With over 85 years of unwavering commitment to advancing animal health through rigorous science, pharmaceutical-grade manufacturing, and a genuinely passion-driven mission to improve the lives of animals and the professionals who care for them, Vetoquinol has established itself as a trusted partner of veterinarians, dairy farmers, and animal health professionals worldwide. Their Indian operations Vetoquinol India Animal Health Pvt. Ltd. deliver the same world-class pharmaceutical standards and innovative product portfolio to the Indian veterinary community, addressing the unique animal health challenges of the Indian subcontinent with globally validated solutions. Vetoquinol's unwavering dedication to scientific excellence, product safety, and genuine animal welfare aligns perfectly with Animeal's mission to provide registered veterinary professionals and dairy farmers across India with reliable, quality-assured access to the best in veterinary pharmaceuticals.

Disclaimer:

Mastiwok Intramammary Infusion is a Schedule H prescription-only veterinary antibiotic product for intramammary use in lactating dairy cattle only. It must be prescribed, dispensed, and administered exclusively by or under the direct supervision of a licensed veterinarian. Strict adherence to the prescribed milk and meat withholding periods is mandatory to ensure consumer food safety and regulatory compliance. Inappropriate use, incorrect administration technique, or failure to observe withholding periods may result in treatment failure, antibiotic residues in milk and meat, and serious regulatory and food safety consequences. Animeal facilitates enquiry and procurement for registered veterinary professionals and licensed dairy farm operators this product is not available for general retail sale. Always refer to the current product data sheet and your prescribing veterinarian's guidance for complete prescribing, administration, and withholding period information.

Frequently Asked Questions

Which mastitis-causing organisms does Mastiwok cover?

Mastiwok's active ingredient, Cefoperazone Sodium, provides broad-spectrum bactericidal coverage against the complete range of gram-positive and gram-negative mastitis pathogens most commonly encountered in Indian dairy cattle. This includes Staphylococcus aureus including many beta-lactamase-producing strains Streptococcus agalactiae, Streptococcus dysgalactiae, Streptococcus uberis, Escherichia coli, Klebsiella spp., Enterobacter spp., and Pseudomonas aeruginosa. This broad-spectrum coverage makes Mastiwok a reliable empirical first-line treatment choice even before culture and sensitivity results are available, ensuring that treatment can begin immediately without delay.

Why is Cefoperazone Sodium preferred over first-generation cephalosporins for mastitis treatment?

Cefoperazone Sodium's third-generation cephalosporin classification offers two significant clinical advantages over first-generation cephalosporins such as Cefazolin for mastitis treatment. First, its significantly enhanced stability against beta-lactamase enzymatic inactivation allows it to maintain bactericidal efficacy against many beta-lactamase-producing staphylococcal and gram-negative strains that would readily inactivate first-generation agents a critical advantage given the increasing prevalence of beta-lactamase-producing Staphylococcus aureus in Indian dairy herds. Second, its extended gram-negative spectrum provides effective coverage against coliform and environmental mastitis pathogens including E. coli and Klebsiella that are not reliably covered by first-generation cephalosporins, making it a more comprehensive therapeutic choice for mixed infections and environmentally-acquired mastitis cases.

What is the correct milk withholding period after Mastiwok treatment?

Milk from quarters treated with Mastiwok must not be used for human consumption during the entire treatment course and for a minimum of 3 to 4 days equivalent to 6 to 8 consecutive milkings after the last intramammary infusion. Strict adherence to the withholding period is mandatory to ensure the complete elimination of antibiotic residues from milk and full compliance with Indian food safety and dairy regulatory requirements. Always confirm the precise withholding period with your prescribing veterinarian and refer to the current product data sheet for the most up-to-date withholding period guidance.

Can Mastiwok be used for both clinical and sub-clinical mastitis?

Yes Mastiwok is indicated and effective for the treatment of both clinically apparent mastitis and sub-clinical mastitis in lactating cows and buffaloes. For clinical mastitis with visible symptoms including abnormal milk, udder swelling, heat, and pain, prompt treatment at the first presentation of signs is strongly recommended to prevent progression to severe systemic illness and permanent udder damage. For sub-clinical mastitis identified by elevated somatic cell count, positive California Mastitis Test, or routine herd screening early treatment with Mastiwok can significantly reduce the duration of infection, prevent spread to other quarters and herd members, and protect long-term milk production and udder health.

How can I enquire about or procure Vetoquinol Mastiwok through Animeal?

Registered veterinary professionals, licensed dairy farm operators, and authorised veterinary pharmaceutical distributors can enquire about Vetoquinol Mastiwok Intramammary Infusion through Animeal's dedicated veterinary pharmaceutical enquiry channel. Please use the Enquire Now button on this product page or contact our veterinary pharma team directly via WhatsApp or phone with your valid veterinary prescription and practice registration details. Our team will respond promptly with product availability, pricing, pack sizes, and delivery arrangements to your registered practice or farm address across India.

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