MEZOLAM INJE

Rapid, Reliable Onset of Action:
Mezolam's unique pH-dependent solubility ensures that your veterinary patient achieves therapeutic CNS sedation within minutes of intravenous administration, with intramuscular bioavailability reaching approximately 91%. This rapid pharmacokinetic profile is critical in emergency scenarios such as status epilepticus, where delayed action can have life-altering consequences for your companion animal.

Superior Muscle Relaxation Without Cardiovascular Compromise:
Unlike many anaesthetic agents, Midazolam achieves profound skeletal muscle relaxation via depression of spinal motor interneurons, without the significant cardiovascular depression associated with barbiturates or high-dose propofol. This makes Mezolam a preferred choice of veterinarians for compromised or haemodynamically unstable patients who require sedation with a minimal cardiac impact.

Dose-Sparing Synergy With Co-Induction Agents:
When used as part of a balanced anaesthetic protocol alongside ketamine, alfaxalone, or alpha-2 agonists, Mezolam significantly reduces the total doses of primary induction agents required, lowering cumulative drug load and supporting smoother induction, better intraoperative muscle tone, and more controlled recovery for your canine or feline patient.

Versatile Multi-Route Administration:
Mezolam's water-soluble formulation supports intravenous, intramuscular, intranasal, and intrarectal administration unlike lipid-soluble benzodiazepines that are restricted to intravenous use due to tissue irritation. This versatility is particularly valuable in emergency field situations or in fractious patients where intravenous access is challenging.

Short-Acting and Fully Reversible:
With a short elimination half-life of approximately 1–6 hours in companion animals and full reversal achievable with flumazenil (a specific benzodiazepine antagonist), Mezolam allows the attending veterinarian to retain precise pharmacological control over the depth and duration of sedation a vital safety feature in critically ill or geriatric patients.

Anticonvulsant Efficacy Backed by Clinical Evidence:
Clinical data in dogs demonstrates that Midazolam delivered via continuous rate infusion achieves seizure control in approximately 77% of cases involving status epilepticus or cluster seizures, positioning Mezolam as one of the most clinically substantiated first- and second-line anticonvulsant options available in veterinary emergency medicine.

How to Use:

Mezolam Injection 5ml must be administered exclusively by a licensed veterinarian or trained veterinary medical professional in a clinical setting equipped with appropriate resuscitation facilities and monitoring equipment. The route of administration intravenous, intramuscular, intranasal, or intrarectal will be selected by the attending veterinarian based on the clinical urgency, patient status, and intended use (pre-anaesthetic, procedural sedation, or emergency anticonvulsant). The injectable solution may be diluted with 0.9% sodium chloride, 5% glucose, Ringer's Lactate, or Hartmann's solution when preparing infusions; diluted solutions should be used within 24 hours at room temperature or within 72 hours if refrigerated at 5°C. Mezolam Injection is compatible with atropine sulfate, glycopyrrolate, ketamine, morphine, fentanyl, and nalbuphine, but compatibility must be confirmed with the dispensing veterinarian before combining with other agents. This product must never be self-administered by the pet owner. If intranasal or intrarectal home administration is specifically prescribed by your veterinarian for emergency seizure management, follow their directions precisely and contact your veterinary clinic immediately following use.

Storage Advice:

Store unopened Mezolam Injection 5ml in a cool, dry place between 15°C and 30°C, protected from direct sunlight and moisture. Do not freeze. As a Schedule H prescription-only controlled substance, Mezolam must be stored in a locked cabinet or secure safe with access restricted to authorised personnel only; monitor remaining quantities regularly to ensure the expected volume is present. Once opened or diluted for infusion, use within 24 hours at room temperature or within 72 hours at 5°C. Do not use after the best-before date printed on the vial label or outer packaging.

About the Brand:

Neon Laboratories Ltd. was incorporated on 22 June 1982 in Mumbai, Maharashtra, and has grown from a family-founded enterprise into one of India's most respected pharmaceutical manufacturers, holding over 14 domestic and international patents across its product portfolio. The company's three manufacturing facilities operate in full compliance with Good Manufacturing Practice (GMP) standards as prescribed by the World Health Organization (WHO), and Neon has established a global supply presence across South Asia, the Middle East, Central America, and beyond. Neon's core scientific philosophy centres on the development and production of Active Pharmaceutical Ingredients and parenteral formulations in the highly specialised domains of anaesthesiology, oncology, and critical care areas where precision and product integrity are non-negotiable. The company's uncompromising commitment to Total Quality Management, first established under the founding leadership of the Jain family, continues to drive every stage of formulation, testing, and delivery. This dedication to pharmaceutical excellence aligns with Animeal's commitment to providing veterinary professionals and informed pet parents with products they can trust unequivocally. Discover Neon Laboratories today.

Disclaimer:

Please note that while Mezolam Injection 5ml is formulated from Midazolam Hydrochloride a clinically validated benzodiazepine and is appropriate for use in dogs, cats, horses, and exotic species under veterinary supervision, it is a prescription-only controlled substance and must not be obtained, stored, or administered without a valid prescription from a licensed veterinarian. This product is not available for over-the-counter purchase and may only be dispensed and administered within a clinical or authorised veterinary setting. For pets with known hypersensitivity to benzodiazepines, pre-existing liver or kidney disease, glaucoma, or respiratory compromise, consult your veterinarian before use, as dose adjustments and heightened monitoring may be required. Animeal supports your pet's health and happiness journey but does not replace the advice of a qualified veterinary professional.