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PRE NATAL CARE
MIFEX LIQUID [5LTR]
MIFEX LIQUID [5LTR]
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About Product
Mifex Oral Suspension, manufactured by Elanco India Pvt Ltd, is a cutting-edge veterinary-grade oral liquid feed supplement specifically formulated to address one of the most economically significant and health-threatening conditions in dairy farming milk fever (hypocalcaemia) and its associated macro-mineral deficiencies, including hypomagnesaemia and hypophosphataemia. Occurring most commonly in high-yielding cattle, buffaloes, sheep, and goats in the periparturient (around-calving) period, these mineral imbalances can cause muscle weakness, recumbency, impaired immune function, reduced milk production, and in severe cases, life-threatening metabolic collapse. Mifex Oral Suspension delivers Calcium, Magnesium, Phosphorus, Vitamin D3, Vitamin B12, and carbohydrates in ideal proportions through a highly bioavailable oral liquid format, making it practical for large-scale herd management and routine supplementation on dairy farms of all sizes. Animeal is proud to offer Mifex Oral Suspension as part of its trusted livestock health portfolio, empowering farmers and veterinary professionals with a reliable solution to protect and optimise the health and productivity of your dairy animals.
Ingredients:
- Calcium (as Dibasic Calcium Phosphate / Calcium Borogluconate): Calcium is the principal macro-mineral in Mifex Oral Suspension. At the cellular level, calcium is essential for muscle contraction including cardiac and smooth muscle nerve impulse transmission, and the secretory processes involved in milk synthesis. During peak lactation, a high-yielding cow can mobilise up to 30g of calcium per day into milk, far exceeding dietary intake, which triggers hypocalcaemia. The dibasic (dicalcium phosphate) form used in oral supplements offers superior bioavailability over elemental calcium sources, facilitating rapid intestinal absorption via active transport mechanisms dependent on Vitamin D3. Calcium is maintained in a 2:1 ratio with phosphorus in this formulation, the scientifically validated ratio for maximum skeletal uptake and homeostatic balance.
- Magnesium: Magnesium (Mg²⁺) plays a pivotal co-regulatory role in calcium metabolism by supporting the activity of parathyroid hormone (PTH) the primary hormonal driver of calcium mobilisation from bone reserves and enhanced intestinal absorption. Magnesium deficiency (hypomagnesaemia) blunts PTH secretion and peripheral tissue responsiveness, directly worsening hypocalcaemia. At the neuromuscular level, adequate magnesium is critical for preventing tetanic spasms, hyperexcitability, and nervous system dysregulation hallmarks of grass tetany in cattle and sheep. Magnesium also serves as a cofactor for ATP synthesis and over 300 enzymatic reactions involved in energy metabolism, protein synthesis, and immune cell function.
- Phosphorus: Phosphorus is the second most abundant mineral in the body and is intrinsically linked to calcium metabolism. It is essential for the formation of hydroxyapatite crystals in bone matrix, ATP (adenosine triphosphate) energy production, phospholipid membrane integrity, and the enzymatic reactions governing carbohydrate and protein metabolism. Hypophosphataemia low blood phosphorus frequently accompanies milk fever and contributes to post-partum recumbency even after calcium correction. The phosphorus in Mifex Oral Suspension restores serum phosphate levels and supports rapid recovery of muscle function and energy metabolism in periparturient animals.
- Vitamin D3 (Cholecalciferol): Vitamin D3 is the master regulator of calcium and phosphorus homeostasis. Once ingested, cholecalciferol is hydroxylated in the liver to 25-hydroxyvitamin D, and subsequently in the kidneys to the biologically active form, 1,25-dihydroxyvitamin D (calcitriol). Calcitriol upregulates the expression of calcium-binding proteins (calbindins) in intestinal epithelial cells, dramatically increasing active calcium absorption from the gut. It also stimulates osteoclast-mediated calcium mobilisation from bone and enhances renal calcium reabsorption. Supplementation with Vitamin D3 in Mifex Oral is critical to ensuring that the calcium and phosphorus delivered in the formulation is fully utilised by your animal's body rather than passing unabsorbed.
- Vitamin B12 (Cyanocobalamin): Vitamin B12 is a water-soluble, cobalt-containing vitamin essential for the synthesis of red blood cells through the maturation of megaloblastic precursors in bone marrow. In ruminants, cobalt-deficient diets impair the ruminal microbial synthesis of B12, leading to metabolic anaemia, weight loss, reduced appetite, and impaired energy metabolism. At the biochemical level, B12 acts as a cofactor for methylmalonyl-CoA mutase a key enzyme in propionate metabolism which is the principal gluconeogenic precursor in ruminants. By supporting this pathway, B12 in Mifex Oral helps maintain energy balance and combat metabolic stress during the high-demand periparturient period.
- Carbohydrates (Dextrose/Glucose): The carbohydrate fraction in Mifex Oral Suspension, primarily in the form of dextrose (glucose), provides an immediate and readily bioavailable source of energy to counter the negative energy balance seen during peak lactation. Dextrose also plays a vital role in preventing acetonaemia (ketosis) a common metabolic disorder in dairy cattle where deficient glucose availability drives the liver to produce ketone bodies, leading to appetite suppression, reduced milk yield, and systemic toxicity. By maintaining adequate blood glucose levels, the carbohydrate component in Mifex Oral directly supports sustained milk production and rapid post-partum recovery.
Features and Benefits
Targets the Root Cause of Milk Fever at the Met...
Targets the Root Cause of Milk Fever at the Metabolic Level:
Mifex Oral Suspension does not merely address symptoms it replenishes the exact macro-minerals and vitamins depleted during periparturient hypocalcaemia, restoring serum calcium, magnesium, and phosphorus to physiologically normal levels. This comprehensive mineral matrix supports faster clinical recovery and reduces the risk of secondary complications such as displaced abomasum and retained placenta.
Enhances Milk Yield Through Nutritional Fortification:
By correcting the mineral and energy deficits that directly suppress mammary gland function, Mifex Oral supports the restoration and optimisation of milk production in your dairy animals. The carbohydrate component provides the glucose substrate necessary for lactose synthesis the primary driver of milk volume while calcium and phosphorus underpin the secretory cell machinery of the udder.
Supports Robust Bone Health and Skeletal Integrity:
The scientifically validated 2:1 calcium-to-phosphorus ratio in Mifex Oral ensures maximum bone mineralisation efficiency, reducing the risk of osteoporosis-related fractures and skeletal weakness in high-producing animals undergoing repeated calving cycles. Vitamin D3 amplifies this effect by maximising intestinal calcium absorption and promoting mineralisation of newly formed bone tissue.
Reinforces Nerve and Muscle Function, Preventing Tetanic Episodes:
Magnesium in Mifex Oral directly reinforces PTH-mediated calcium mobilisation and maintains neuromuscular excitability thresholds, preventing the dangerous hyperexcitability and muscle spasms associated with grass tetany and lactation tetany. This protective action is critical in grazing animals on lush pastures during spring and autumn the highest-risk seasons for hypomagnesaemic tetany.
Combats Acetonaemia and Restores Energy Balance:
The dextrose and Vitamin B12 complex in Mifex Oral work synergistically to maintain blood glucose levels and support propionate metabolism, the cornerstone of gluconeogenesis in ruminants. This dual-action energy support alleviates the clinical signs of ketosis including appetite loss, weight decline, and reduced milk yield helping your animal return to optimal metabolic health faster.
Practical Large-Volume Oral Format for Farm-Scale Use:
Available in a convenient 5-litre HDPE jar, Mifex Oral Suspension is formulated for straightforward administration directly into the feed or as a drench, eliminating the need for intravenous administration in non-emergency scenarios. This makes it the preferred choice of dairy farmers and veterinarians for routine herd-level supplementation and early-stage clinical management.
Usage and Applications
How to Use:Mifex Oral Suspension is administere...
How to Use:
Mifex Oral Suspension is administered orally, either as a drench or mixed into feed, as directed by a qualified veterinarian or livestock nutritionist. Shake the container thoroughly before each use to ensure uniform dispersion of the mineral suspension. The frequency and quantity of administration should be determined based on the animal's species, body weight, stage of lactation, and severity of the mineral deficiency always follow your veterinarian's specific recommendations for your herd. For routine prophylactic supplementation, the product may be incorporated into daily feeding schedules during the pre-calving dry period and early lactation phase. For clinical cases of milk fever or acute mineral deficiency, veterinary consultation is essential before initiating oral supplementation, as severe cases may require concurrent intravenous therapy. Ensure clean, calibrated drenching equipment is used for accurate delivery, and wear gloves when handling large volumes of the suspension. Do not administer to animals that are unable to swallow or are in a state of recumbency without veterinary guidance.
Storage Advice:
Store unopened Mifex Oral Suspension 5 Litre in a cool, dry place below 25°C away from direct sunlight. Do not freeze. Once opened, secure the HDPE jar lid tightly after each use and store in a shaded, well-ventilated area to prevent mineral sedimentation and microbial contamination. Shake the container thoroughly before each subsequent use to restore suspension uniformity. Do not use after the best-before date printed on the jar label or base.
About the Brand:
Elanco Animal Health Incorporated traces its origins to 1954, when it was established as part of Eli Lilly and Company, with its first FDA-approved veterinary product marking the foundation of a science-driven legacy in animal health. Today, Elanco operates as an independent, publicly listed global leader one of the top animal health companies in the world with a portfolio of over 200 brands sold across more than 90 countries, backed by rigorous R&D investment and a commitment to evidence-based veterinary science. Elanco's product philosophy centres on developing solutions that simultaneously improve animal wellbeing, support food production sustainability, and empower the farmers, veterinarians, and animal health professionals who depend on reliable science every day. The company's "Elanco Healthy Purpose framework reflects deep ESG commitments including goals to help farmers reduce their environmental footprint and advance food security for millions in emerging markets, including India. Elanco's ethos of making life better for animals aligns seamlessly with Animeal's commitment to delivering trustworthy, high-quality animal health products to every pet and livestock owner in India discover Elanco today.
Disclaimer:
Please note that while Mifex Oral Suspension is formulated from calcium, magnesium, phosphorus, Vitamin D3, Vitamin B12, and carbohydrates and is appropriate for cattle, buffaloes, goats, sheep, and other dairy livestock, it is a complementary feed supplement and is not a substitute for a complete, balanced livestock diet nor a replacement for prescribed veterinary therapy in clinically severe cases. In animals presenting with acute recumbency, severe neurological signs, or unresponsiveness consistent with advanced milk fever, oral administration alone is not sufficient and intravenous calcium therapy under veterinary supervision must be prioritised. For livestock with pre-existing renal impairment, chronic metabolic disorders, or history of hypercalcaemia, consult your veterinarian before introducing this product. Animeal supports your pet's and livestock's health and happiness journey but does not replace the advice of a qualified veterinary professional.
