MUCOMIX INJ
In Stock
Mucomix Injection by Samarth Life Sciences is a prescription-only, clinically critical injectable formulation of N-Acetylcysteine (NAC), designed to address two of the most urgent medical emergencies encountered in both human and veterinary clinical settings paracetamol (acetaminophen) toxicity and the management of thick, obstructive mucus secretions in respiratory tract diseases. Paracetamol overdose is one of the leading causes of acute liver failure, and the therapeutic window for effective intervention is dangerously narrow making the rapid, accurate administration of this antidote a life-or-death decision. Simultaneously, in conditions such as bronchitis, emphysema, bronchiectasis, and cystic fibrosis, excessive and viscous mucus can severely compromise airway patency and respiratory function. Mucomix Injection targets both these pathologies through a single, well-established active molecule with decades of clinical validation. Animeal is proud to offer Mucomix Injection as part of our curated selection of critical care pharmaceutical solutions for veterinary use, available for prescription-guided purchase through our platform.
Ingredients:
N-Acetylcysteine (NAC) 400 mg per 2 ml ampoule: (N-acetyl-L-cysteine; CAS No. 616-91-1) N-Acetylcysteine is a synthetic derivative of the naturally occurring amino acid L-cysteine, and its therapeutic action operates across two distinct but interconnected physiological pathways.
As a Mucolytic Agent: NAC directly targets the disulfide bonds within the glycoprotein matrix of mucus. At the biochemical level, its free thiol (-SH) group cleaves the disulfide bridges that maintain the structural rigidity and high viscosity of mucus polymers. This depolymerisation of mucus macromolecules reduces mucosal viscosity and elasticity, facilitating mucociliary clearance and making expectoration significantly easier. This action alleviates airway obstruction and improves respiratory function in conditions characterised by mucus hypersecretion.
As a Hepatoprotective Antidote: In the context of paracetamol toxicity, NAC functions as both a direct precursor to glutathione (GSH) and as a direct antioxidant. When paracetamol is metabolised in excess, the cytochrome P450 enzyme system generates a highly reactive hepatotoxic metabolite, N-acetyl-p-benzoquinone imine (NAPQI). Under normal conditions, NAPQI is rapidly conjugated and neutralised by hepatic glutathione. In overdose scenarios, glutathione stores become rapidly depleted, allowing NAPQI to accumulate and covalently bind to hepatocellular proteins, triggering oxidative stress, mitochondrial dysfunction, and ultimately necrotic cell death. NAC replenishes intracellular cysteine stores the rate-limiting substrate for glutathione biosynthesis thereby restoring GSH levels, neutralising NAPQI, and protecting hepatocytes from irreversible damage. Additionally, NAC exerts direct antioxidant activity, scavenging reactive oxygen species (ROS) independently of the GSH pathway, and improves microcirculatory blood flow in the liver, further reinforcing hepatic recovery.
