OCUVIR 800 DT TABLET
Out of Stock
Prescription Required
Ocuvir 800 DT Tablet by FDC Limited is a prescription-only, high-strength dispersible antiviral formulation containing Acyclovir 800mg, engineered to target serious herpesvirus infections in companion animals. It addresses clinically significant viral conditions caused by alpha-herpesviruses, including herpes simplex virus infections, herpes zoster (shingles), and varicella-zoster virus (chickenpox), by disrupting viral DNA replication at the intracellular level and halting the propagation of infection through host tissue. The dispersible tablet format ensures flexible, precise administration, particularly important in veterinary contexts where swallowing intact tablets may be challenging and where dose titration is critical. In veterinary medicine, Acyclovir has been used in the management of canine herpesvirus-1 infections and, under strict veterinary supervision with careful species-specific caution, as part of antiviral management protocols in select cases. Animeal is proud to offer Ocuvir 800 DT Tablet as part of its curated prescription pharmaceutical range, supporting informed, responsible antiviral care for your companion animal.
Ingredients:
Acyclovir 800mg per dispersible tablet:
Acyclovir is a synthetic acyclic purine nucleoside analogue of deoxyguanosine, the naturally occurring nucleoside building block of DNA. Its antiviral action is exquisitely selective and depends on a multi-step phosphorylation cascade that is initiated almost exclusively in virus-infected cells. Upon entering a herpesvirus-infected cell, acyclovir is first phosphorylated to acyclovir monophosphate by viral thymidine kinase (TK), an enzyme expressed specifically by herpesvirus-infected cells and virtually absent in uninfected host cells. This first phosphorylation step is the critical selectivity gate that concentrates the drug's activity in infected cells while largely sparing healthy tissue. Host cellular kinases then convert acyclovir monophosphate sequentially to acyclovir diphosphate and finally to the active triphosphate form, acyclovir triphosphate. Acyclovir triphosphate competitively inhibits viral DNA polymerase with approximately 30 to 50 times greater affinity than it inhibits mammalian cellular DNA polymerase, thereby achieving targeted viral suppression. Additionally, when acyclovir triphosphate is incorporated into the growing viral DNA chain in place of deoxyguanosine triphosphate, it acts as an obligate chain terminator: the absence of a 3-prime hydroxyl group on its acyclic sugar moiety prevents further elongation of the DNA strand, permanently halting viral genome replication. This dual action of competitive enzyme inhibition and irreversible DNA chain termination makes acyclovir a potent and highly selective antiviral agent against susceptible herpesviruses.
