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EYE AND EAR CARE
OFLOX SYRUP
OFLOX SYRUP
By CIPLA
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About Product
Oflox 0.3% Eye/Ear Drops, manufactured by Cipla Ltd., is a precision-formulated, broad-spectrum fluoroquinolone antibiotic solution designed to target and eliminate bacterial infections of the eye and external ear canal. Whether your pet is struggling with the discomfort of bacterial conjunctivitis, corneal ulceration, otitis externa, or chronic suppurative otitis media, Oflox 0.3% delivers targeted antimicrobial action directly to the site of infection, alleviating redness, discharge, swelling, and pain with clinical efficacy. This prescription-grade ophthalmic and otic solution is trusted by veterinarians globally for its rapid onset, documented tissue penetration, and established safety profile across species. Animeal is proud to offer Oflox 0.3% Eye/Ear Drops as part of its curated range of veterinary-grade pharmaceutical solutions, making advanced infection management accessible for your beloved companion.
Ingredients
Ofloxacin (Ofloxacinum) 0.3% w/v (3 mg per ml):Ofloxacin is a second-generation fluoroquinolone antibiotic with a well-characterised dual mechanism of bacterial eradication. At the molecular level, it targets and inhibits two essential bacterial enzymes: DNA gyrase (topoisomerase II) and topoisomerase IV. These enzymes are responsible for the supercoiling, relaxation, and segregation of bacterial DNA during replication and transcription. By binding to the enzyme-DNA complex and forming a ternary complex, ofloxacin introduces double-strand breaks into the bacterial chromosome that the cell cannot repair, ultimately causing rapid bactericidal death. Crucially, these enzymes differ structurally from mammalian topoisomerases, which explains the selective toxicity to bacteria and the favourable safety profile in host tissue. Ofloxacin demonstrates superior aqueous penetration when applied topically, with studies confirming meaningful concentration levels in the corneal stroma and aqueous humour following instillation, ensuring adequate drug delivery at the site of infection. Its broad-spectrum activity covers organisms including Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Enterobacter cloacae, Haemophilus influenzae, and Proteus mirabilis, among others.
Benzalkonium Chloride (Benzalkonii Chloridum) as Preservative:Benzalkonium chloride is a quaternary ammonium compound that functions as an antimicrobial preservative, maintaining the sterility of the multi-dose formulation between applications. It disrupts microbial cell membrane integrity through electrostatic interaction with the phospholipid bilayer, preventing contamination of the solution during the course of treatment. Its inclusion also contributes mildly to the overall antimicrobial environment at the application surface.
Excipients: Purified water, sodium chloride, and other pH-adjusting and tonicity-balancing agents formulated to maintain physiological compatibility with ocular and aural mucosa.
Features and Benefits
Rapid, targeted bacterial clearance: Oflox 0.3%...
Rapid, targeted bacterial clearance: Oflox 0.3% delivers active ofloxacin directly to infected ocular and aural tissue, achieving bactericidal concentrations that disrupt DNA replication at the cellular level. Consistent application restores healthy tissue appearance and resolves hallmark infection symptoms such as purulent discharge, erythema, and periocular crusting within the prescribed treatment window.
Broad-spectrum efficacy across common pathogens: The fluoroquinolone class targets a wide range of gram-positive and gram-negative bacteria that commonly colonise the eye and ear canal in animals. This positions Oflox 0.3% as a cutting-edge first-line option for empirical treatment while culture and sensitivity results are awaited.
Proven corneal tissue penetration: Clinical pharmacokinetic studies confirm that topically applied ofloxacin 0.3% achieves therapeutically relevant concentrations within the corneal stroma and anterior chamber, making it particularly effective in cases of bacterial corneal ulceration. This depth of penetration ensures that infections at the corneal surface and within superficial stromal layers are adequately managed.
Dual-purpose ophthalmic and otic formulation: The sterile, pH-balanced solution is specifically formulated for safe use in both the eye and ear, offering veterinary practitioners and pet parents convenience without compromising clinical performance. The gentle isotonic formulation minimises local irritation and supports mucosal tolerance during extended treatment courses.
Manufactured to pharmaceutical-grade standards by Cipla Ltd.: Produced by one of India's most globally respected and WHO-GMP-certified pharmaceutical manufacturers, Oflox 0.3% meets the highest quality benchmarks for sterility, potency, and shelf stability. Each batch undergoes rigorous quality assurance testing to ensure consistent and reliable performance.
Prescription-grade infection control from a trusted brand: As a prescription-only medicine, Oflox 0.3% is positioned as a preferred choice of veterinarians for managing bacterial infections of the eye and ear in clinical and home-care settings. Its proven track record over decades of use reinforces its place as a cornerstone antimicrobial in veterinary ophthalmology and otology.
Usage and Applications
How to Use:Oflox 0.3% Eye/Ear Drops must be adm...
How to Use:
Oflox 0.3% Eye/Ear Drops must be administered only under the direction and prescription of a qualified veterinarian. Prior to each application, wash your hands thoroughly with soap and water to prevent introducing additional contaminants to the treated area. For ocular administration, gently hold your pet's head still and tilt it slightly upward. Using your non-dominant hand, carefully pull down the lower eyelid to create a small conjunctival pocket. Hold the dropper bottle above the eye without allowing the tip to contact the ocular surface, eyelids, or lashes, and instil the prescribed number of drops directly into the conjunctival sac. Allow your pet to blink naturally, and gently hold the eyelids closed for approximately one minute to encourage absorption and reduce drainage. For aural administration, position your pet so the affected ear faces upward. Gently lift and fold the pinna back to straighten the ear canal, then instil the prescribed number of drops into the canal entrance. Massage the base of the ear gently for 30 to 60 seconds to facilitate distribution of the solution within the canal. Avoid inserting the dropper tip into the canal. Always recap the bottle immediately after use. Complete the full prescribed course of treatment even if clinical improvement is visible before completion, as premature discontinuation may result in bacterial resistance or treatment relapse. If redness, excessive discharge, or behavioural signs of pain worsen or do not improve within 48 hours of commencing treatment, contact your veterinarian immediately.
Storage Advice:
Store unopened Oflox 0.3% Eye/Ear Drops in a cool, dry place below 30 degrees Celsius, away from direct sunlight and sources of heat or moisture. Do not freeze. Once opened, keep the bottle tightly capped and use within 28 days; discard any remaining solution after this period to prevent administration of a potentially contaminated or degraded preparation. Do not use after the best-before date printed on the bottle label and outer carton. Keep this medication out of the reach of children and animals. This product is for external use only and must not be taken orally.
About the Brand:
Cipla Ltd. was founded in 1935 in Mumbai, India, by Dr. Khwaja Abdul Hamied, with the pioneering vision of making medicines affordable and accessible to all. Today, Cipla is a global pharmaceutical leader operating in over 80 countries, recognised for its WHO-GMP-certified manufacturing facilities and adherence to the highest international regulatory standards including USFDA, MHRA, and TGA approvals. Cipla's research and development philosophy centres on delivering clinically proven, quality-assured medicines that address real patient and patient-guardian needs, spanning from primary care to specialised therapeutic areas including ophthalmology and infectious disease management. The company's commitment to quality, transparency, and accessible healthcare is reflected in every product it manufactures and aligns with Animeal's commitment to providing only the safest, most effective veterinary-grade solutions for your beloved companions. Discover Cipla's trusted pharmaceutical range today through Animeal.
Disclaimer:
Please note that while Oflox 0.3% Eye/Ear Drops is formulated from ofloxacin, a broad-spectrum fluoroquinolone antibiotic, and is appropriate for use in companion animals under veterinary supervision, it is a prescription-only pharmaceutical medicine and is not a substitute for a thorough veterinary diagnosis, clinical examination, or a tailored treatment plan. This product must not be used without a valid prescription from a licensed veterinarian. Self-administration without professional guidance may result in incorrect diagnosis, inappropriate use, or the development of antimicrobial resistance. For pets with known hypersensitivity to fluoroquinolone antibiotics, a history of tendon disorders, epilepsy, cardiac arrhythmias, or concurrent ocular or aural conditions of unknown aetiology, consult your veterinarian before introducing this product. Animeal supports your pet's health and happiness journey but does not replace the advice of a qualified veterinary professional.
