OFLOX SYRUP
In Stock
Oflox 0.3% Eye/Ear Drops, manufactured by Cipla Ltd., is a precision-formulated, broad-spectrum fluoroquinolone antibiotic solution designed to target and eliminate bacterial infections of the eye and external ear canal. Whether your pet is struggling with the discomfort of bacterial conjunctivitis, corneal ulceration, otitis externa, or chronic suppurative otitis media, Oflox 0.3% delivers targeted antimicrobial action directly to the site of infection, alleviating redness, discharge, swelling, and pain with clinical efficacy. This prescription-grade ophthalmic and otic solution is trusted by veterinarians globally for its rapid onset, documented tissue penetration, and established safety profile across species. Animeal is proud to offer Oflox 0.3% Eye/Ear Drops as part of its curated range of veterinary-grade pharmaceutical solutions, making advanced infection management accessible for your beloved companion.
Ingredients
Ofloxacin (Ofloxacinum) 0.3% w/v (3 mg per ml):Ofloxacin is a second-generation fluoroquinolone antibiotic with a well-characterised dual mechanism of bacterial eradication. At the molecular level, it targets and inhibits two essential bacterial enzymes: DNA gyrase (topoisomerase II) and topoisomerase IV. These enzymes are responsible for the supercoiling, relaxation, and segregation of bacterial DNA during replication and transcription. By binding to the enzyme-DNA complex and forming a ternary complex, ofloxacin introduces double-strand breaks into the bacterial chromosome that the cell cannot repair, ultimately causing rapid bactericidal death. Crucially, these enzymes differ structurally from mammalian topoisomerases, which explains the selective toxicity to bacteria and the favourable safety profile in host tissue. Ofloxacin demonstrates superior aqueous penetration when applied topically, with studies confirming meaningful concentration levels in the corneal stroma and aqueous humour following instillation, ensuring adequate drug delivery at the site of infection. Its broad-spectrum activity covers organisms including Staphylococcus aureus, Streptococcus pneumoniae, Pseudomonas aeruginosa, Enterobacter cloacae, Haemophilus influenzae, and Proteus mirabilis, among others.
Benzalkonium Chloride (Benzalkonii Chloridum) as Preservative:Benzalkonium chloride is a quaternary ammonium compound that functions as an antimicrobial preservative, maintaining the sterility of the multi-dose formulation between applications. It disrupts microbial cell membrane integrity through electrostatic interaction with the phospholipid bilayer, preventing contamination of the solution during the course of treatment. Its inclusion also contributes mildly to the overall antimicrobial environment at the application surface.
Excipients: Purified water, sodium chloride, and other pH-adjusting and tonicity-balancing agents formulated to maintain physiological compatibility with ocular and aural mucosa.
