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IMMUNITY SUPPLEMENTS
POLYBION LC SYRUP
POLYBION LC SYRUP
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Polybion LC Paediatric Mango Flavour Syrup 300ml, manufactured and marketed by Procter and Gamble Health Limited (formerly Merck Limited India), is a sugar-free, alcohol-free, 100% vegetarian oral nutritional supplement formulated with a clinically relevant combination of B-complex vitamins and the essential amino acid Lysine Hydrochloride. Each 5ml serving delivers Pyridoxine Hydrochloride (Vitamin B6) 0.75mg, Nicotinamide (Vitamin B3) 15mg, Cyanocobalamin (Vitamin B12) 2mcg, and Lysine Hydrochloride 375mg in a palatable, mango-flavoured sorbitol base, making it an accessible, everyday nutritional supplement for supporting energy metabolism, appetite, immunity, and healthy growth and development. While primarily formulated for human paediatric use, B-complex vitamins and lysine supplementation have documented nutritional relevance in companion animal health, particularly in young, growing, or convalescent animals where dietary nutritional gaps, reduced appetite, or increased metabolic demand may create a clinical need for targeted micronutrient and amino acid support. Animeal is proud to offer Polybion LC Paediatric Mango Flavour Syrup as a complementary nutritional solution within its curated wellness catalogue, helping pet parents support their companion animals' daily nutritional balance and vitality.
Ingredients:
Pyridoxine Hydrochloride (Vitamin B6): Pyridoxine Hydrochloride is the hydrochloride salt form of Vitamin B6, a water-soluble coenzyme that is essential for over 100 enzymatic reactions in the body, predominantly those involving amino acid metabolism. In its active coenzyme form, pyridoxal-5-phosphate (PLP), it serves as a cofactor for aminotransferases and decarboxylases, directly facilitating the transamination and decarboxylation reactions that govern the synthesis and catabolism of amino acids. This makes it indispensable for protein utilization from dietary sources, as well as for the biosynthesis of critical neurotransmitters including serotonin (from tryptophan), dopamine (from DOPA), gamma-aminobutyric acid (GABA), and norepinephrine. Pyridoxine additionally supports carbohydrate and fat metabolism, participates in haemoglobin synthesis by enabling the formation of delta-aminolevulinic acid (a haem precursor), and reinforces immune cell proliferation and antibody production. In animals, Vitamin B6 deficiency manifests as impaired growth, microcytic anaemia, neurological signs, and dermatitis, making adequate dietary supply critical for growing and convalescent companion animals.
Nicotinamide (Vitamin B3, Niacinamide): Nicotinamide is the amide form of Vitamin B3 (niacin) and serves as the direct precursor to the two universal cellular coenzymes nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide phosphate (NADP+). These coenzymes are among the most centrally important molecules in cellular biochemistry, functioning as hydride ion acceptors and donors across the electron transport chain in mitochondrial oxidative phosphorylation, the citric acid cycle, fatty acid beta-oxidation, and glycolysis. Without adequate NAD+ and NADP+, cellular ATP generation is severely compromised, resulting in fatigue, weakness, and metabolic dysfunction. Nicotinamide additionally supports DNA repair mechanisms via its role as a substrate for poly-ADP-ribose polymerases (PARPs), contributes to skin barrier function and integrity, and plays a role in the regulation of inflammatory cytokine pathways. Unlike niacin, nicotinamide does not cause the vasodilatory flushing response, making it the preferred form for supplemental use. In companion animals, B3 deficiency presents as pellagra-like dermatitis, poor coat condition, gastrointestinal disturbance, and neurological changes.
Cyanocobalamin (Vitamin B12): Cyanocobalamin is a stabilized, synthetic form of Vitamin B12, which upon absorption is converted in the body to the two active coenzyme forms methylcobalamin and adenosylcobalamin. Methylcobalamin is essential for the methionine synthase reaction that converts homocysteine to methionine, directly supporting DNA methylation, the one-carbon metabolic cycle, and the regeneration of tetrahydrofolate (active folate). Adenosylcobalamin functions as a cofactor in the methylmalonyl-CoA mutase reaction, enabling the metabolism of odd-chain fatty acids and branched-chain amino acids. Vitamin B12 is uniquely critical for the production and maturation of red blood cells in bone marrow; its deficiency leads to megaloblastic anaemia characterized by large, immature, non-functional erythrocytes and impaired oxygen delivery. It is equally essential for the maintenance of myelin sheath integrity around peripheral and central nervous system axons, with B12 deficiency producing demyelinating neuropathy that manifests as weakness, ataxia, and cognitive changes. Because Vitamin B12 is found predominantly in animal-based foods and requires specific intrinsic factor-mediated absorption in the terminal ileum, deficiency is particularly common in animals with gastrointestinal disease, malabsorption, or exocrine pancreatic insufficiency.
Lysine Hydrochloride (L-Lysine): Lysine is an indispensable essential amino acid that cannot be synthesized endogenously by mammals and must therefore be supplied through diet or supplementation. Structurally, lysine's epsilon-amino group makes it uniquely important in cross-linking collagen fibrils via hydroxylysine formation, a reaction catalyzed by lysyl hydroxylase with ascorbate as cofactor. This structural role makes lysine critical for the integrity of connective tissue, wound healing, bone matrix formation, and skin and coat health. At the metabolic level, lysine is the primary precursor of carnitine, a molecule essential for the transport of long-chain fatty acids across the inner mitochondrial membrane for beta-oxidation and energy generation. The carnitine biosynthetic pathway requires both lysine and methionine as substrates, with pyridoxine and niacin serving as cofactors, highlighting the synergistic nutritional relationship between the components of this formula. Lysine also reinforces immune function by supporting the production of antibodies, immune effector cells, and the complement system. In the context of animal nutrition, lysine serves as a critical appetite stimulant and growth-supporting amino acid, and adequate lysine intake is associated with improved feed conversion efficiency, lean muscle accretion, and overall vigour in growing animals.
Sorbitol Solution 70% (Non-Crystallising): Sorbitol serves as the vehicle and sweetening agent in this formulation, providing a palatable liquid base without sucrose, making the product suitable for animals with glucose metabolism concerns. It additionally has mild osmotic properties that support intestinal motility.
POLYBION LC SYRUP
Out of Stock
Polybion LC Paediatric Mango Flavour Syrup 300ml, manufactured and marketed by Procter and Gamble Health Limited (formerly Merck Limited India), is a sugar-free, alcohol-free, 100% vegetarian oral nutritional supplement formulated with a clinically relevant combination of B-complex vitamins and the essential amino acid Lysine Hydrochloride. Each 5ml serving delivers Pyridoxine Hydrochloride (Vitamin B6) 0.75mg, Nicotinamide (Vitamin B3) 15mg, Cyanocobalamin (Vitamin B12) 2mcg, and Lysine Hydrochloride 375mg in a palatable, mango-flavoured sorbitol base, making it an accessible, everyday nutritional supplement for supporting energy metabolism, appetite, immunity, and healthy growth and development. While primarily formulated for human paediatric use, B-complex vitamins and lysine supplementation have documented nutritional relevance in companion animal health, particularly in young, growing, or convalescent animals where dietary nutritional gaps, reduced appetite, or increased metabolic demand may create a clinical need for targeted micronutrient and amino acid support. Animeal is proud to offer Polybion LC Paediatric Mango Flavour Syrup as a complementary nutritional solution within its curated wellness catalogue, helping pet parents support their companion animals' daily nutritional balance and vitality.
Ingredients:
Pyridoxine Hydrochloride (Vitamin B6): Pyridoxine Hydrochloride is the hydrochloride salt form of Vitamin B6, a water-soluble coenzyme that is essential for over 100 enzymatic reactions in the body, predominantly those involving amino acid metabolism. In its active coenzyme form, pyridoxal-5-phosphate (PLP), it serves as a cofactor for aminotransferases and decarboxylases, directly facilitating the transamination and decarboxylation reactions that govern the synthesis and catabolism of amino acids. This makes it indispensable for protein utilization from dietary sources, as well as for the biosynthesis of critical neurotransmitters including serotonin (from tryptophan), dopamine (from DOPA), gamma-aminobutyric acid (GABA), and norepinephrine. Pyridoxine additionally supports carbohydrate and fat metabolism, participates in haemoglobin synthesis by enabling the formation of delta-aminolevulinic acid (a haem precursor), and reinforces immune cell proliferation and antibody production. In animals, Vitamin B6 deficiency manifests as impaired growth, microcytic anaemia, neurological signs, and dermatitis, making adequate dietary supply critical for growing and convalescent companion animals.
Nicotinamide (Vitamin B3, Niacinamide): Nicotinamide is the amide form of Vitamin B3 (niacin) and serves as the direct precursor to the two universal cellular coenzymes nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide phosphate (NADP+). These coenzymes are among the most centrally important molecules in cellular biochemistry, functioning as hydride ion acceptors and donors across the electron transport chain in mitochondrial oxidative phosphorylation, the citric acid cycle, fatty acid beta-oxidation, and glycolysis. Without adequate NAD+ and NADP+, cellular ATP generation is severely compromised, resulting in fatigue, weakness, and metabolic dysfunction. Nicotinamide additionally supports DNA repair mechanisms via its role as a substrate for poly-ADP-ribose polymerases (PARPs), contributes to skin barrier function and integrity, and plays a role in the regulation of inflammatory cytokine pathways. Unlike niacin, nicotinamide does not cause the vasodilatory flushing response, making it the preferred form for supplemental use. In companion animals, B3 deficiency presents as pellagra-like dermatitis, poor coat condition, gastrointestinal disturbance, and neurological changes.
Cyanocobalamin (Vitamin B12): Cyanocobalamin is a stabilized, synthetic form of Vitamin B12, which upon absorption is converted in the body to the two active coenzyme forms methylcobalamin and adenosylcobalamin. Methylcobalamin is essential for the methionine synthase reaction that converts homocysteine to methionine, directly supporting DNA methylation, the one-carbon metabolic cycle, and the regeneration of tetrahydrofolate (active folate). Adenosylcobalamin functions as a cofactor in the methylmalonyl-CoA mutase reaction, enabling the metabolism of odd-chain fatty acids and branched-chain amino acids. Vitamin B12 is uniquely critical for the production and maturation of red blood cells in bone marrow; its deficiency leads to megaloblastic anaemia characterized by large, immature, non-functional erythrocytes and impaired oxygen delivery. It is equally essential for the maintenance of myelin sheath integrity around peripheral and central nervous system axons, with B12 deficiency producing demyelinating neuropathy that manifests as weakness, ataxia, and cognitive changes. Because Vitamin B12 is found predominantly in animal-based foods and requires specific intrinsic factor-mediated absorption in the terminal ileum, deficiency is particularly common in animals with gastrointestinal disease, malabsorption, or exocrine pancreatic insufficiency.
Lysine Hydrochloride (L-Lysine): Lysine is an indispensable essential amino acid that cannot be synthesized endogenously by mammals and must therefore be supplied through diet or supplementation. Structurally, lysine's epsilon-amino group makes it uniquely important in cross-linking collagen fibrils via hydroxylysine formation, a reaction catalyzed by lysyl hydroxylase with ascorbate as cofactor. This structural role makes lysine critical for the integrity of connective tissue, wound healing, bone matrix formation, and skin and coat health. At the metabolic level, lysine is the primary precursor of carnitine, a molecule essential for the transport of long-chain fatty acids across the inner mitochondrial membrane for beta-oxidation and energy generation. The carnitine biosynthetic pathway requires both lysine and methionine as substrates, with pyridoxine and niacin serving as cofactors, highlighting the synergistic nutritional relationship between the components of this formula. Lysine also reinforces immune function by supporting the production of antibodies, immune effector cells, and the complement system. In the context of animal nutrition, lysine serves as a critical appetite stimulant and growth-supporting amino acid, and adequate lysine intake is associated with improved feed conversion efficiency, lean muscle accretion, and overall vigour in growing animals.
Sorbitol Solution 70% (Non-Crystallising): Sorbitol serves as the vehicle and sweetening agent in this formulation, providing a palatable liquid base without sucrose, making the product suitable for animals with glucose metabolism concerns. It additionally has mild osmotic properties that support intestinal motility.
