RABIGEN MONO INJ 1 ML
In Stock
Prescription Required
Virbac Rabigen Mono the globally recommended, veterinarian-trusted inactivated rabies vaccine formulated for the active immunisation of dogs, cats, cattle, horses, and in principle all mammals against rabies. Rabies remains one of the most devastating and invariably fatal zoonotic viral diseases known to medicine a disease that kills tens of thousands of people and countless animals worldwide every year, and one for which there is no cure once clinical signs appear. Vaccination is the single most effective intervention available to protect your pet against this deadly virus, fulfil your legal obligation as a responsible pet parent in India, and contribute to the global drive towards rabies elimination. Rabigen Mono, containing the inactivated VP12 rabies virus strain at a potency of greater than 1.0 International Units per dose meeting and exceeding the minimum protective threshold established by international regulatory authorities is internationally recognised for achieving high virus-neutralising antibody (VNA) titres that confer reliable, long-lasting immune protection. As an approved veterinary vaccine imported and distributed in India by Virbac Animal Health India Pvt. Ltd. under CDSCO Import Permit IMP-248/2014, and manufactured by the world's sixth largest pure-play veterinary biopharmaceutical group, Rabigen Mono is the most trusted anti-rabies vaccine available to Indian pet parents and veterinary professionals today. Animeal is proud to offer this life-saving vaccine to every dog and cat parent across India.
Composition:
- Inactivated VP12 Rabies Virus Strain >1.0 International Units (IU) per dose: The VP12 strain is a fixed, cell-culture-adapted rabies virus strain propagated under controlled laboratory conditions, inactivated using established viricidal processes that eliminate all live viral replication capacity while preserving the immunogenic surface glycoprotein (rG) structures critical for triggering a protective immune response. The minimum potency threshold of >1.0 IU per dose is the global standard established by the WHO and OIE (World Organisation for Animal Health) as the minimum titre required to confer protective immunity against field rabies virus challenge in vaccinated animals. Rabigen Mono consistently meets and exceeds this threshold, producing high virus-neutralising antibody (VNA) titres following vaccination the measurable immunological marker of protective immunity. The immune response to inactivated rabies vaccine is driven primarily by the generation of VNA directed against the rabies glycoprotein, with protective titres achieved within 14 to 28 days of primary vaccination and sustained through the recommended annual or triennial booster schedule.
- Aluminium Hydroxide Gel 10% v/v (Adjuvant): Aluminium hydroxide (alum) is the most widely used and extensively safety-characterised vaccine adjuvant in both human and veterinary immunology. As a depot adjuvant, aluminium hydroxide slows the release of the inactivated viral antigen from the injection site, prolonging antigen presentation to the immune system and dramatically amplifying the magnitude, quality, and duration of the humoral (antibody-mediated) immune response compared to antigen alone. Alum promotes uptake by antigen-presenting cells (APCs), enhances B-cell activation and antibody class-switching, and supports the generation of long-lived plasma cells and memory B-cells the cellular basis for sustained immunological protection between booster doses.
- Thiomersal IP 0.01% w/v (Preservative): An organomercury preservative used at a very low, pharmacopoeially specified concentration to prevent microbial contamination of the multi-dose vaccine vial throughout its in-use period. Thiomersal at 0.01% w/v is the internationally accepted standard preservative concentration in veterinary vaccines, ensuring sterility and potency are maintained between successive draws from multi-dose presentations without adversely affecting vaccine immunogenicity.
