Rexidin M Forte Gel by Indoco Remedies is a cutting-edge triple-action prescription dental gel formulated to target the pain, infection, and inflammation associated with mouth ulcers (aphthous stomatitis), gingivitis, and other oral mucosal conditions. Oral ulcers and gum infections are not merely cosmetic concerns; left unmanaged, they disrupt eating, drinking, and speaking while creating a cycle of bacterial proliferation that delays healing. Rexidin M Forte Gel addresses all three dimensions of this cycle simultaneously: it alleviates pain at the site, eliminates pathogenic bacteria, and reinforces mucosal integrity to accelerate recovery. Animeal is proud to offer this trusted, clinician-recommended formulation for those seeking rapid, multi-targeted oral relief.
Ingredients:
Chlorhexidine Gluconate 1% w/w: Chlorhexidine Gluconaten is a broad-spectrum bisguanidine antiseptic with documented bactericidal and bacteriostatic activity. At the cellular level, it disrupts the integrity of both gram-positive and gram-negative bacterial cell membranes by binding to negatively charged phospholipid bilayer components, causing cytoplasmic leakage and eventual cellular lysis. In the oral environment, it adsorbs strongly to mucosal tissues, salivary proteins, and tooth surfaces, creating a sustained-release reservoir that provides residual antimicrobial protection for several hours following application. This substantivity effect is critical for controlling plaque-forming organisms such as Streptococcus mutans and Porphyromonas gingivalis, both of which are key drivers of periodontal disease progression.
Metronidazole 1% w/w: Metronidazole is a nitroimidazole antibiotic with targeted activity against anaerobic bacteria and protozoa. Once it enters microbial cells, it undergoes reductive activation by nitroreductase enzymes present specifically in anaerobic organisms. The resulting reactive nitro-radical intermediates interact with DNA strands, causing strand breakage, loss of helical structure, and irreversible inhibition of nucleic acid synthesis, ultimately leading to microbial cell death. Metronidazole's anaerobic specificity makes it particularly effective in the periodontal pocket environment and within infected mucosal lesions, where oxygen-depleted conditions favor the growth of the most destructive periodontal pathogens.
Lidocaine 2% w/w (Lignocaine): Lidocaine is a short-acting amide-class local anesthetic that targets voltage-gated sodium channels in peripheral sensory neurons. By reversibly binding to and blocking the intracellular portion of Nav channels, Lidocaine prevents the influx of sodium ions necessary for depolarization and propagation of the nociceptive (pain) impulse. At the concentration present in this gel, it acts topically to provide rapid desensitization of the ulcer site upon application. In addition, the gel base itself forms a thin physical film over the mucosal lesion, providing a mechanical barrier that shields exposed nerve endings from contact stimuli such as food, saliva, and temperature changes.
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