ANTI BIOTIC

SAFELOX OD BOLUS

SAFELOX OD BOLUS

By INDO-SAFE

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About Product

Safelox OD (Enrofloxacin 200mg Bolus) is a broad-spectrum, once-daily veterinary antibiotic bolus formulated for the treatment of bacterial infections in large animals including cattle, calves, sheep, goats, and pigs. Belonging to the fluoroquinolone carboxylic acid derivative class, Safelox OD delivers potent bactericidal action against a wide range of Gram-negative and Gram-positive pathogens making it a preferred choice among veterinarians for respiratory, digestive, urinary, reproductive, and dermatological infections. Animeal is proud to offer Safelox OD as part of its carefully curated veterinary medicine range, aligned with our commitment to reliable, high-quality animal healthcare solutions.

Composition

  • Enrofloxacin IP 200mg: The active fluoroquinolone compound; inhibits bacterial DNA gyrase enzyme, blocking DNA and RNA synthesis and delivering rapid bactericidal activity against susceptible organisms.
  • Excipients q.s.: Pharmaceutical-grade binders and carriers ensuring bolus integrity, palatability, and consistent release of the active ingredient.

Features and Benefits

Broad-Spectrum Bactericidal Action: Safelox OD ...

Broad-Spectrum Bactericidal Action: Safelox OD targets and eliminates a wide range of Gram-negative bacteria including E. coli, Pasteurella multocida, Klebsiella spp., Mannheimia haemolytica, Salmonella spp. and selected Gram-positive organisms including Staphylococcus aureus and Mycoplasma spp.

Once-Daily Dosing (OD Formula): The 200mg bolus strength is engineered for single daily administration in large animals, reducing handling stress, improving compliance, and simplifying treatment protocols on farm.

Rapid Absorption & Tissue Penetration: Enrofloxacin is quickly absorbed from the gastrointestinal tract and distributes into all major body tissues and fluids including lungs, kidneys, skin, uterus, and joints achieving therapeutic concentrations within 1 to 2 hours of dosing.

Dual Elimination Pathway: Eliminated via both renal and hepatic routes, allowing effective use even in animals with mildly compromised kidney function without significant dosage adjustment.

Targets Multiple Infection Sites: Clinically effective for respiratory tract infections (BRD), gastrointestinal infections, urinary tract infections, mastitis (E. coli-associated), Mycoplasma-induced arthritis in calves, metritis, and skin/wound infections.

Active Metabolite Advantage: Metabolised in the liver to ciprofloxacin, an equally potent active metabolite, extending the drug's antibacterial duration and spectrum beyond the parent compound alone.

Usage and Applications

How to UseAdminister Safelox OD orally as a bol...

How to Use

Administer Safelox OD orally as a bolus. Ensure accurate body weight measurement before dosing to prevent underdosing or adverse effects.

Recommended Dosage (as directed by a veterinarian):

Cattle/Buffalo 5 mg/kg body weight Once daily 3–5 days

Calves 5 mg/kg body weight Once daily 3–5 days

Sheep/Goats 5 mg/kg body weight Once daily3 days

Pigs 2.5 mg/kg body weight Once daily 3 days

Treatment should continue for at least 2–3 days beyond the cessation of clinical signs. Maximum duration of therapy is 30 days. Always follow the dosage schedule as prescribed by your registered veterinarian.

Contraindications:

  • Do not use in animals with known hypersensitivity to enrofloxacin or other fluoroquinolones.
  • Avoid use in young, growing animals due to risk of articular cartilage damage.
  • Do not use in pregnant or lactating animals unless explicitly directed by a veterinarian.
  • Do not use concurrently with antacids, iron supplements, or calcium-rich feed as these may reduce drug absorption.

Do not use in animals producing milk for human consumption unless the stated withdrawal period can be strictly observed.

Storage Advice

Store Safelox OD boluses in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children and non-target animals. Do not use after the expiry date printed on the packaging. Ensure packaging is properly resealed after each use.

About the Brand Safelox / Safe Laboratories

Safelox is manufactured by a trusted Indian veterinary pharmaceutical manufacturer committed to producing high-efficacy, quality-assured animal health products. With a focus on practical large-animal healthcare, Safelox's range of antibiotic boluses is formulated to meet the rigorous demands of farm veterinary practice across India. Animeal proudly partners with quality-driven domestic pharma manufacturers to bring accessible, vet-grade solutions to pet owners, livestock farmers, and animal care professionals across the country.

Disclaimer

Safelox OD Enrofloxacin 200mg Bolus is a prescription veterinary medicine. It must only be used under the supervision and prescription of a licensed veterinarian. Animeal provides accurate product information for reference purposes only and does not substitute professional veterinary advice. Dosage, duration, and suitability must be assessed by a qualified veterinarian based on the individual animal's condition, weight, and medical history. Misuse of antibiotics may contribute to antimicrobial resistance.

Frequently Asked Questions

Is Safelox OD suitable for all large animals?

Safelox OD is formulated for cattle, buffalo, calves, sheep, goats, and pigs. It is not recommended for use in young growing animals, pregnant or lactating females, or animals with known hypersensitivity to fluoroquinolone antibiotics. Always consult your veterinarian to confirm suitability for your specific animal before beginning treatment.

How often should Safelox OD be administered?

Safelox OD is an once-daily (OD) bolus, meaning it is administered just once every 24 hours. The treatment duration typically ranges from 3 to 5 days depending on the severity of the infection and the animal species being treated. Always follow the dosage schedule prescribed by your registered veterinarian.

How effective is Safelox OD against respiratory and digestive infections?

Safelox OD is clinically proven to be highly effective against Bovine Respiratory Disease (BRD), gastrointestinal infections caused by E. coli and Salmonella spp., urinary tract infections, and Mycoplasma-associated conditions. Its rapid tissue penetration ensures therapeutic concentrations are achieved in the lungs, gut, and other target organs within 1–2 hours of administration.

Are there any side effects associated with Safelox OD?

Safelox OD is generally well tolerated when used as directed. However, some animals may experience mild gastrointestinal disturbances such as reduced appetite or loose stools during the course of treatment. Prolonged use or overdosing may lead to cartilage damage in young animals or neurological signs in sensitive individuals. Discontinue use and consult your veterinarian immediately if adverse reactions are observed.

How can I purchase Safelox OD from Animeal?

Safelox OD is a prescription veterinary medicine available on Animeal.in. To place your order, simply upload a valid veterinary prescription through our website or WhatsApp us directly at +91-9004157093. Our team will verify your prescription and process your order with fast 3–4 day delivery across India.