ANTI BIOTIC
SAFELOX OD BOLUS
SAFELOX OD BOLUS
By INDO-SAFE
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About Product
Safelox OD (Enrofloxacin 200mg Bolus) is a broad-spectrum, once-daily veterinary antibiotic bolus formulated for the treatment of bacterial infections in large animals including cattle, calves, sheep, goats, and pigs. Belonging to the fluoroquinolone carboxylic acid derivative class, Safelox OD delivers potent bactericidal action against a wide range of Gram-negative and Gram-positive pathogens making it a preferred choice among veterinarians for respiratory, digestive, urinary, reproductive, and dermatological infections. Animeal is proud to offer Safelox OD as part of its carefully curated veterinary medicine range, aligned with our commitment to reliable, high-quality animal healthcare solutions.
Composition
- Enrofloxacin IP 200mg: The active fluoroquinolone compound; inhibits bacterial DNA gyrase enzyme, blocking DNA and RNA synthesis and delivering rapid bactericidal activity against susceptible organisms.
- Excipients q.s.: Pharmaceutical-grade binders and carriers ensuring bolus integrity, palatability, and consistent release of the active ingredient.
Features and Benefits
Broad-Spectrum Bactericidal Action: Safelox OD ...
Broad-Spectrum Bactericidal Action: Safelox OD targets and eliminates a wide range of Gram-negative bacteria including E. coli, Pasteurella multocida, Klebsiella spp., Mannheimia haemolytica, Salmonella spp. and selected Gram-positive organisms including Staphylococcus aureus and Mycoplasma spp.
Once-Daily Dosing (OD Formula): The 200mg bolus strength is engineered for single daily administration in large animals, reducing handling stress, improving compliance, and simplifying treatment protocols on farm.
Rapid Absorption & Tissue Penetration: Enrofloxacin is quickly absorbed from the gastrointestinal tract and distributes into all major body tissues and fluids including lungs, kidneys, skin, uterus, and joints achieving therapeutic concentrations within 1 to 2 hours of dosing.
Dual Elimination Pathway: Eliminated via both renal and hepatic routes, allowing effective use even in animals with mildly compromised kidney function without significant dosage adjustment.
Targets Multiple Infection Sites: Clinically effective for respiratory tract infections (BRD), gastrointestinal infections, urinary tract infections, mastitis (E. coli-associated), Mycoplasma-induced arthritis in calves, metritis, and skin/wound infections.
Active Metabolite Advantage: Metabolised in the liver to ciprofloxacin, an equally potent active metabolite, extending the drug's antibacterial duration and spectrum beyond the parent compound alone.
Usage and Applications
How to UseAdminister Safelox OD orally as a bol...
How to Use
Administer Safelox OD orally as a bolus. Ensure accurate body weight measurement before dosing to prevent underdosing or adverse effects.
Recommended Dosage (as directed by a veterinarian):
Cattle/Buffalo 5 mg/kg body weight Once daily 3–5 days
Calves 5 mg/kg body weight Once daily 3–5 days
Sheep/Goats 5 mg/kg body weight Once daily3 days
Pigs 2.5 mg/kg body weight Once daily 3 days
Treatment should continue for at least 2–3 days beyond the cessation of clinical signs. Maximum duration of therapy is 30 days. Always follow the dosage schedule as prescribed by your registered veterinarian.
Contraindications:
- Do not use in animals with known hypersensitivity to enrofloxacin or other fluoroquinolones.
- Avoid use in young, growing animals due to risk of articular cartilage damage.
- Do not use in pregnant or lactating animals unless explicitly directed by a veterinarian.
- Do not use concurrently with antacids, iron supplements, or calcium-rich feed as these may reduce drug absorption.
Do not use in animals producing milk for human consumption unless the stated withdrawal period can be strictly observed.
Storage Advice
Store Safelox OD boluses in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children and non-target animals. Do not use after the expiry date printed on the packaging. Ensure packaging is properly resealed after each use.
About the Brand Safelox / Safe Laboratories
Safelox is manufactured by a trusted Indian veterinary pharmaceutical manufacturer committed to producing high-efficacy, quality-assured animal health products. With a focus on practical large-animal healthcare, Safelox's range of antibiotic boluses is formulated to meet the rigorous demands of farm veterinary practice across India. Animeal proudly partners with quality-driven domestic pharma manufacturers to bring accessible, vet-grade solutions to pet owners, livestock farmers, and animal care professionals across the country.
Disclaimer
Safelox OD Enrofloxacin 200mg Bolus is a prescription veterinary medicine. It must only be used under the supervision and prescription of a licensed veterinarian. Animeal provides accurate product information for reference purposes only and does not substitute professional veterinary advice. Dosage, duration, and suitability must be assessed by a qualified veterinarian based on the individual animal's condition, weight, and medical history. Misuse of antibiotics may contribute to antimicrobial resistance.