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INJECTABLE
TAXIM INJ 1GM
TAXIM INJ 1GM
By ALKEM
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About Product
Taxim Injection 1gm by Alkem Laboratories is a third-generation cephalosporin antibiotic indicated for the management of serious, moderate-to-severe bacterial infections affecting multiple organ systems in animals. It targets one of the most critical clinical challenges in veterinary medicine: infections caused by both Gram-positive and Gram-negative bacteria, particularly those resistant to first- and second-generation antibiotics or conventional penicillin-class drugs. Available as a sterile powder for reconstitution, each single-dose vial contains 1000mg (1gm) of Cefotaxime Sodium and is administered exclusively via intravenous or intramuscular injection by a licensed veterinary professional. Taxim 1gm is the preferred choice of veterinarians for managing acute sepsis, respiratory tract infections, urinary tract infections, skin and soft tissue infections, bone and joint infections, and bacterial meningitis in dogs and cats. Animeal is proud to offer Taxim Injection 1gm as part of its curated range of prescription-grade veterinary medicines for critical care.
Ingredients:
Cefotaxime Sodium (1000mg per vial): Cefotaxime Sodium is the active pharmaceutical ingredient in Taxim Injection 1gm and belongs to the third-generation cephalosporin class of beta-lactam antibiotics. At the molecular level, Cefotaxime exerts its bactericidal action by irreversibly binding to Penicillin-Binding Proteins (PBPs), enzymes located on the inner membrane of bacterial cell walls that are essential for the cross-linking of peptidoglycan strands. Peptidoglycan is the structural polymer that provides rigidity, integrity, and protective function to the bacterial cell wall. By blocking PBP-mediated transpeptidation, Cefotaxime prevents the formation and repair of peptidoglycan chains, thereby compromising cell wall integrity. This causes an osmotic imbalance, leading to rupture of the bacterial cell membrane, cellular lysis, and ultimately bacterial death. Cefotaxime is resistant to hydrolysis by many bacterial beta-lactamases, including extended-spectrum beta-lactamases (ESBLs), which makes it effective against a wide range of resistant Gram-negative organisms such as Enterobacteriaceae. It demonstrates strong bactericidal activity against Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Haemophilus influenzae, Streptococcus pneumoniae, and Staphylococcus aureus (non-MRSA strains), among others. Critically, Cefotaxime crosses the blood-brain barrier, making it a valuable agent in the treatment of bacterial meningitis and sepsis involving the central nervous system in companion animals.
Sodium Content (as part of the sodium salt formulation): Cefotaxime is formulated as its sodium salt to improve aqueous solubility, enabling rapid and complete reconstitution for injection. The sodium content in each 1gm vial is approximately 48mg (approximately 2.09 mEq), which is clinically relevant for patients requiring sodium restriction and should be considered when managing animals with concurrent cardiac or renal conditions.
Features and Benefits
Broad-Spectrum Bactericidal Efficacy:
Taxim Inj...
Broad-Spectrum Bactericidal Efficacy:
Taxim Injection 1gm targets a wide range of Gram-positive and Gram-negative bacterial pathogens, making it one of the most versatile injectable antibiotics available in critical veterinary care. Its ability to overcome many beta-lactamase-mediated resistance mechanisms ensures effective bactericidal action even against organisms that have developed resistance to older antibiotic classes.
Critical Coverage Across Multiple Organ Systems:
This injectable antibiotic effectively reaches therapeutic concentrations in the lungs, urinary tract, skin, bones, joints, abdominal cavity, and bloodstream of your canine companion or feline friend. Its ability to penetrate the blood-brain barrier sets it apart from most cephalosporins, allowing it to address life-threatening bacterial meningitis and CNS sepsis that other antibiotics cannot reach.
Rapid Onset in Acute and Life-Threatening Infections:
When administered intravenously in a hospital setting, Cefotaxime achieves peak plasma concentrations rapidly, delivering immediate bactericidal action at the site of infection. This makes Taxim 1gm the antibiotic of choice when your pet presents with acute sepsis, severe infection, or deteriorating clinical status that demands swift intervention.
Effective Where Other Antibiotics Have Failed:
The beta-lactamase stability of Cefotaxime Sodium means it remains active against strains resistant to first-generation cephalosporins and penicillins, making it a critical rescue option in complicated bacterial infections. It is particularly valuable in patients who cannot safely receive aminoglycosides due to pre-existing kidney conditions.
Hospital-Grade Sterile Formulation:
Each single-dose vial of Taxim Injection 1gm is manufactured as a sterile lyophilised powder that reconstitutes into a clear, injectable solution, meeting hospital-grade pharmaceutical standards. This ensures consistent potency, sterility, and safety with every dose administered by your veterinary professional.
Usage and Applications
How to Use:Taxim Injection 1gm is a prescriptio...
How to Use:
Taxim Injection 1gm is a prescription-only injectable antibiotic and must be reconstituted and administered exclusively by a licensed veterinarian or trained veterinary professional in a clinical setting. Do not attempt to self-administer this product. The veterinarian will reconstitute the sterile powder with an appropriate diluent such as sterile water for injection or normal saline before administration. The injection may be given intravenously (directly into a vein) or intramuscularly (into a muscle), as directed by the attending veterinarian. Intravenous administration is strongly preferred in companion animals due to the risk of pain, induration, and injection-site reactions associated with intramuscular delivery. The dosage, frequency of administration, and duration of treatment will be determined entirely by the veterinarian based on the type and severity of the infection, the species of the patient, body weight, organ function, and culture-sensitivity findings. The full course of treatment must be completed as prescribed, even if clinical signs appear to resolve before the course is finished, to prevent bacterial relapse and the development of antibiotic resistance. Inform your veterinarian of all medications your pet is currently receiving before commencing treatment with Taxim Injection 1gm.
Storage Advice:
Store unopened Taxim Injection 1gm vials in a cool, dry place between 10 degrees Celsius and 25 degrees Celsius, away from direct sunlight and moisture. Do not freeze. Once reconstituted, the solution must be used immediately and any unused portion must be discarded safely; the reconstituted solution should not be stored for subsequent use. Keep all vials out of the sight and reach of children and animals. This is a prescription-only medicine and must be stored and handled by authorised veterinary personnel only. Do not use after the best-before date printed on the vial label and outer carton.
About the Brand:
Alkem Laboratories Limited is one of India's leading pharmaceutical companies, founded in 1973, and is consistently ranked among the top ten pharmaceutical companies in the country by domestic sales. Alkem holds WHO-GMP certifications across its manufacturing facilities and maintains a robust global presence, exporting to over 50 countries across multiple regulated and semi-regulated markets. The brand's research and development philosophy is centred on delivering high-quality, affordable medicines across therapeutic categories including anti-infectives, central nervous system drugs, and critical care formulations, backed by rigorous clinical and pharmacological standards. Alkem's unwavering commitment to consistent quality, scalable manufacturing, and evidence-based medicine aligns with Animeal's commitment to offering only trusted, clinically sound pharmaceutical options for your pet's health and recovery. Discover Alkem Laboratories today.
Disclaimer:
Please note that while Taxim Injection 1gm is formulated with Cefotaxime Sodium 1000mg, a third-generation cephalosporin antibiotic with proven broad-spectrum bactericidal activity, it is a prescription-only injectable pharmaceutical product and must not be purchased, stored, or administered without a valid prescription from a licensed veterinarian. This product is a human-label pharmaceutical used in companion animals as an extra-label drug under veterinary supervision; it is not independently licensed for veterinary use by a regulatory authority. It is not a substitute for a comprehensive veterinary diagnosis, culture and sensitivity testing, or an established antimicrobial stewardship protocol. For pets with known hypersensitivity to cefotaxime, other cephalosporins, or beta-lactam antibiotics, this product is strictly contraindicated. For pets with pre-existing renal impairment, hepatic disease, cardiac conditions, or seizure disorders, consult your veterinarian before introducing this product. Animeal supports your pet's health and happiness journey but does not replace the advice of a qualified veterinary professional.
