EYE AND EAR CARE
TRAVATAN EYE DROP
TRAVATAN EYE DROP
By ALCON
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About Product
Travatan 40mcg/ml Eye Drops Solution 2.5ml, manufactured by Alcon Inc., is a prescription-grade sterile ophthalmic solution containing Travoprost at a concentration of 40 micrograms per millilitre as its active pharmaceutical ingredient. Belonging to the prostaglandin analogue class of intraocular pressure-lowering agents, Travatan targets the root haemodynamic mechanism of elevated intraocular pressure by enhancing the outflow of aqueous humour from the eye through the uveoscleral pathway, delivering clinically significant and sustained reductions in intraocular pressure (IOP) with a single evening drop per day. Elevated intraocular pressure is the primary modifiable risk factor for glaucoma, a progressive optic neuropathy that is among the leading causes of irreversible blindness in both humans and companion animals. In veterinary medicine, Travoprost ophthalmic solution is used off-label under specialist prescription primarily in dogs diagnosed with primary or secondary open-angle glaucoma and ocular hypertension, where it has demonstrated meaningful IOP-lowering efficacy through the uveoscleral outflow pathway. Travatan's FDA-approved formulation contains Polyquaternium-1 (POLYQUAD) as a preservative, offering a gentler ocular surface profile compared to benzalkonium chloride-preserved alternatives. Animeal is proud to offer Travatan 40mcg/ml Eye Drops Solution 2.5ml as part of its curated veterinary ophthalmology prescription catalogue, supporting veterinary specialists and animal owners in delivering cutting-edge, evidence-based ocular care to their canine companions.
Ingredients:
Travoprost:Travoprost is a synthetic fluorinated prostaglandin F2 alpha (PGF2 alpha) analogue and a highly selective, full agonist at the FP prostanoid receptor subtype. It is formulated as a prodrug in the ester form, which is biologically inactive until hydrolyzed by corneal esterase enzymes following topical ocular instillation. Upon penetration through the corneal epithelium, travoprost is rapidly converted by these esterases to its pharmacologically active free acid form, travoprost free acid, which then binds with high affinity to FP receptors located in the ciliary body and trabecular meshwork.
Polyquaternium-1 (POLYQUAD) 10 micrograms/ml:Polyquaternium-1 is a polymeric quaternary ammonium compound used as the ophthalmic preservative in this formulation. Unlike benzalkonium chloride, which exerts membrane-disrupting toxicity to corneal epithelial cells and disrupts the tear film, Polyquaternium-1 functions as a large polymeric molecule that is too large to penetrate corneal epithelial cells, providing antimicrobial preservation while minimizing cytotoxicity to the ocular surface. This results in a superior corneal tolerability profile, making Travatan with POLYQUAD a preferred option for animals requiring prolonged ophthalmic therapy.
Propylene Glycol (7.5 mg/ml): Propylene glycol serves as a tonicity-adjusting co-solvent and humectant in the formulation, contributing to the isotonicity and physical stability of the solution and supporting comfortable instillation on the ocular surface.
Polyoxyethylene Hydrogenated Castor Oil 40 (HCO-40) 2 mg/ml: This non-ionic surfactant acts as a solubilizer for travoprost, which is inherently poorly water-soluble in its free acid form, ensuring uniform drug distribution throughout the aqueous solution and consistent dose delivery with each drop.
Features and Benefits
How to Use:Travatan 40mcg/ml Eye Drops must be ...
How to Use:
Travatan 40mcg/ml Eye Drops must be used only as directed by a prescribing ophthalmologist or veterinary ophthalmologist. In veterinary patients, this product must be administered by the owner under direct instruction and dosing guidance from a licensed veterinary specialist; the dose, frequency, and treatment duration will be determined by the attending veterinary professional based on the individual animal's clinical assessment, IOP measurements, and overall ocular health.
Storage Advice:
Store unopened Travatan 40mcg/ml Eye Drops in a cool, dry place between 2 degrees Celsius and 25 degrees Celsius, away from direct sunlight and heat sources. Do not freeze. Once opened, use within four weeks and do not store beyond this period; write the date of opening on the carton at the time of first use. Keep the bottle tightly closed when not in use. Do not use after the expiry date printed on the bottle and carton. Store out of reach of children and non-target animals at all times.
About the Brand:
Alcon Inc. was founded in 1945 as a small ophthalmic pharmacy in Fort Worth, Texas, by pharmacists Robert Alexander and William Conner, with an original focus on developing sterile ophthalmic products that set the standard for eye care. Over eight decades, Alcon has grown into the world's largest dedicated eye care company, incorporated in Switzerland with global operations across more than 70 countries, and holds FDA approval, EMA authorization, and a portfolio of ISO-certified, cGMP-compliant manufacturing facilities that are at the forefront of ophthalmic pharmaceutical and surgical device innovation. Alcon introduced Travatan ophthalmic solution in 2001, establishing it as a clinically validated, globally recognized first-line prostaglandin analogue for glaucoma management, and has continuously refined the formulation through extensive post-approval research, including the development of the preservative-improved POLYQUAD-preserved variant to better serve patients requiring long-term ocular therapy. Guided by a mission to help people see brilliantly, Alcon's R&D investment spans pharmaceutical eye drops, intraocular lenses, surgical systems, and contact lens technologies, reflecting an uncompromising commitment to advancing every dimension of eye health across all patient populations. This dedication to evidence-based, precision ophthalmic care aligns with Animeal's commitment to bringing veterinary-grade, clinically validated prescription products to the animals and animal owners who need them most. Discover Alcon today.
Disclaimer:
Please note that while Travatan 40mcg/ml Eye Drops Solution 2.5ml is formulated from travoprost, a clinically validated prostaglandin F2 alpha analogue, and is FDA-approved for the reduction of elevated intraocular pressure in human patients with open-angle glaucoma and ocular hypertension, it is a prescription-only ophthalmic pharmaceutical, and its use in dogs and other animals is off-label and must be authorized, dosed, and supervised exclusively by a licensed veterinary ophthalmologist or veterinary specialist with expertise in ocular disease management. This product is not effective for angle-closure, inflammatory, or neovascular glaucoma, and should be used with caution in animals with active uveitis, anterior lens luxation, or known risk factors for macular oedema. Skin contact with the solution must be avoided as travoprost is absorbed transdermally and may have biological activity. For companion animals with a history of intraocular inflammation, posterior capsular disruption, or sensitivity to prostaglandin analogues, consult your veterinary ophthalmologist before introducing this product. Animeal supports your pet's health and happiness journey but does not replace the advice of a qualified veterinary professional.