ZENTONIL CHEW TABLET (S)

Pharmaceutical-Grade SAMe with Patented Microencapsulation Technology:
The most critical determinant of SAMe supplement efficacy is bioavailability SAMe is highly labile and is rapidly destroyed by stomach acid in standard formulations. Each SAMe particle in Zentonil Chew is individually microencapsulated and enteric-coated before incorporation into the palatable chew, a patented gastric-resistant delivery system that ensures SAMe reaches the small intestine intact for peak absorption. This delivery technology is what separates Zentonil from generic SAMe supplements and reinforces its standing as the preferred choice of veterinarians in clinical hepatology practice worldwide.

Rapid Restoration of Depleted Glutathione Stores:
The most clinically urgent consequence of hepatic disease is the collapse of glutathione synthesis stripping liver cells of their primary defence against oxidative injury and toxin accumulation. Zentonil's SAMe directly restores the hepatic SAMe pool, reinvigorating the transsulfuration pathway and restoring GSH synthesis to protective levels, actively decelerating the oxidative cascade that drives further hepatocellular death. This glutathione-replenishing action is the biochemical cornerstone of Zentonil's hepatoprotective efficacy.

Multi-Botanical, Multi-Mechanism Hepatic Protection:
Unlike single-ingredient hepatic supplements, Zentonil Chew combines five distinct active agents SAMe, silybin-phospholipid complex, Vitamin E, Boswellia serrata, and Curcuma longa that target hepatic disease through different, complementary molecular pathways simultaneously. This multi-targeted approach addresses free-radical scavenging, membrane phospholipid repair, 5-LOX and NF-κB-mediated inflammatory suppression, and Nrf2-pathway cytoprotection in a single, convenient daily chew, delivering a breadth of hepatic support that no single-ingredient product can match.

Enhanced Silybin Bioavailability Through Phospholipid Complexation:
Plain silybin has poor oral bioavailability due to its low lipid solubility. Vetoquinol's formulation incorporates silybin pre-complexed with phosphatidylcholine a technology that dramatically amplifies intestinal absorption of this clinically important hepatoprotectant by enabling lymphatic uptake. This means your canine or feline companion receives measurably more active silybin per dose compared to standard milk thistle or silymarin products, translating the well-established hepatoprotective pharmacology of this botanical into real-world clinical benefit.

Cognitive Support for Senior Pets:
Beyond the liver, SAMe's role as the universal methyl donor in the nervous system makes Zentonil uniquely valuable for senior dogs and cats experiencing age-related cognitive decline. SAMe supports the methylation of monoamine neurotransmitters including dopamine, serotonin, and norepinephrine neurochemicals central to mood, alertness, and cognitive function making this a rare hepatic supplement that simultaneously reinforces neurological health in your ageing companion.

Palatable, Flexible-Administration Chew Format:
Zentonil Chews are palatable and flavoured, eliminating the daily struggle of medicating reluctant or food-selective pets. The chew can be given whole, split in two, crushed and mixed with food, or administered directly by hand all without compromising the integrity of the enteric-coated SAMe particles, which are individually protected at the microparticle level rather than relying on a tablet coating. This flexibility makes compliant, consistent daily dosing straightforward even for the most discerning feline or canine patients.

How to Use:

Zentonil Chew must be administered under veterinary supervision and following your veterinarian's specific dosage recommendation. The general dosing guideline is one Zentonil 200 mg chew daily per 10 kg of body weight in both dogs and cats, but your veterinarian may adjust this based on your companion's clinical condition, concurrent medications, and biochemical response. For optimal SAMe absorption, Zentonil is ideally administered on an empty stomach at least 30 minutes before a meal. The chew may be given directly by hand, split in half, crushed and mixed into a small quantity of food, or administered whole the enteric-coated microparticles of SAMe will remain protected regardless of the administration method chosen. Do not administer to human patients. Keep out of reach of children. This product is for animal use only and must not be self-prescribed; always use as directed by your veterinarian. If your companion is concurrently receiving medications metabolised by the liver, inform your veterinarian before commencing Zentonil supplementation.

Storage Advice:

Store unopened Vetoquinol Zentonil Chew in a cool, dry place below 25°C, away from direct sunlight and moisture. Do not freeze. Once the pack is opened, ensure the closure is resealed tightly after each use to protect the enteric-coated SAMe particles from humidity and air exposure, which can degrade bioavailability over time. Do not use after the best-before date printed on the packaging.

About the Brand:

Vetoquinol S.A. was founded in 1933 in Lure, north-eastern France, by pharmacist Joseph Frechin, whose pioneering use of oxyquinoline in animal treatment gave birth to one of the world's most enduring and respected veterinary pharmaceutical names. Over nine decades, Vetoquinol has grown from a single-dispensary origin into one of the top ten global veterinary pharmaceutical laboratories, with a direct presence in 24 countries and product distribution across more than 80 nations remaining an independent, family-owned enterprise throughout, a distinction that underpins its unwavering commitment to veterinary science over shareholder expediency. The company's R&D philosophy centres on developing clinically validated, evidence-based veterinary solutions across companion animal and livestock medicine, with a product portfolio spanning pharmaceuticals, nutraceuticals, and dietary supplements rigorously developed and tested to meet the exacting standards of international veterinary practice. Vetoquinol's global presence in the Asia-Pacific region, including India, reflects its mission to make world-class veterinary hepatology support accessible to companion animals and their caregivers wherever they live. This dedication to science, quality, and animal health aligns with Animeal's commitment to offering pet parents products of the highest global standard. Discover Vetoquinol today.

Disclaimer:

Please note that while Vetoquinol Zentonil Chew is formulated from clinically validated nutraceutical actives SAMe, silybin-phospholipid complex, Vitamin E, Boswellia serrata, Curcuma longa, and Apium graveolens and is appropriate for dogs and cats with hepatic health concerns, it is a complementary nutraceutical supplement and is not a replacement for prescribed veterinary therapy, diagnostic investigation, or medical management of underlying hepatic disease. Zentonil Chew should only be administered under the guidance of a licensed veterinarian who has assessed your pet's liver function and confirmed its suitability for your companion's specific clinical presentation. For pets with severe hepatic failure, concurrent use of multiple medications, or known sensitivity to any of the listed botanicals, consult your veterinarian before use. Animeal supports your pet's health and happiness journey but does not replace the advice of a qualified veterinary professional.