FONDATONE LOTION
In Stock
SAVAVET FONDATONE TOPICAL LOTION (30ML) is a topical solution containing Mometasone Furoate 0.1% in a specially formulated lotion base, presented in a 30ml bottle fitted with a precise spray pump for accurate, mess-free application. It belongs to the therapeutic class of topical corticosteroids specifically classified as a medium-to-high potency synthetic glucocorticoid with exceptional anti-inflammatory and antipruritic activity. FONDATONE is indicated for use in both dogs and cats for the management of allergic dermatitis and, when combined with appropriate antibiotic or antifungal therapy, for the treatment of otitis externa. It is a prescription (Rx) veterinary medicine and must only be used under direct veterinary supervision.
Ingredients:
- Mometasone Furoate 0.1% w/v (Active Ingredient): a synthetic fluorinated corticosteroid belonging to the glucocorticoid class. Mometasone Furoate is one of the most potent and selective topical corticosteroids available, offering a superior therapeutic profile compared to older corticosteroids like hydrocortisone or betamethasone at lower concentrations. Its mechanism of action is multi-layered: It binds with high affinity to intracellular glucocorticoid receptors in skin cells, triggering a cascade of anti-inflammatory gene expression changes that suppress the production of pro-inflammatory mediators including prostaglandins, leukotrienes, cytokines (IL-1, IL-2, IL-6, TNF-α), and histamine It reduces vascular permeability directly decreasing the redness, swelling, heat, and tissue oedema associated with allergic and inflammatory skin reactions It suppresses the activity of mast cells, eosinophils, and T-lymphocytes that drive the chronic itch-scratch cycle in atopic dermatitis It reduces sebaceous gland secretion and modulates keratinocyte proliferation, supporting the restoration of a healthy skin barrier It has a highly favourable systemic safety profile due to its extremely low percutaneous absorption rate particularly important for long-term dermatological use in dogs and cats
- Lotion Base: a precisely formulated vehicle that includes isopropyl alcohol, propylene glycol, hydroxypropylcellulose, and purified water. The lotion base optimises the penetration of Mometasone Furoate into the dermal layers where inflammation originates, while maintaining appropriate pH (~4.5) for skin compatibility. The light, fast-drying lotion format is particularly suitable for hairy and furry skin areas on dogs and cats, as it penetrates without leaving heavy residue or matting the coat
