ITRAVET 200MG TABLET
Out of Stock
Prescription Required
Itravet 200 mg Tablets by Health Kare is a prescription-strength systemic antifungal medication formulated to address a wide spectrum of fungal infections in dogs and cats, including superficial dermatophyte infections such as ringworm, as well as more serious systemic mycoses including blastomycosis, cryptococcosis, and aspergillosis. Fungal diseases in companion animals can be challenging to diagnose and slow to resolve, frequently requiring weeks to months of consistent treatment to fully eradicate the pathogen. Itravet 200 mg delivers Itraconazole at a high-strength 200 mg tablet dose, enabling precise weight-based dosing as directed by your veterinarian. Animeal is proud to offer Itravet 200 mg Tablets as part of its curated range of veterinarian-recommended prescription medicines for the health and recovery of your beloved canine and feline companions.
Ingredients:
Itraconazole- 200 mg per tablet: Itraconazole is a synthetic triazole antifungal agent that targets the fungal cytochrome P450-dependent enzyme 14-alpha-sterol demethylase, which is an essential catalyst in the biosynthesis of ergosterol, the primary structural sterol of fungal cell membranes. By inhibiting this enzyme, Itraconazole causes ergosterol depletion and an accumulation of 14-alpha-methylsterols within the fungal cell. This disrupts the integrity, fluidity, and permeability of the fungal membrane, resulting in leakage of cellular contents, impaired nutrient uptake, and ultimately fungistatic or fungicidal action depending on the organism and concentration achieved. Itraconazole has a broad spectrum of activity spanning dermatophytes (including Microsporum canis, Trichophyton spp.), dimorphic fungi (Blastomyces dermatitidis, Cryptococcus neoformans, Histoplasma capsulatum), and opportunistic moulds (Aspergillus spp.). Notably, Itraconazole accumulates at high concentrations in skin, hair, and nail tissue several times greater than plasma levels conferring sustained antifungal activity even during dose-free intervals, which is a pharmacokinetic advantage particularly important in dermatophyte infections.
