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ONFYTE SHAMPOO
ONFYTE SHAMPOO
By ARANEX
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About Product
Onfyte Multi-Infection Shampoo by Aranex is a clinically formulated, medicated veterinary shampoo that delivers dual-action antibacterial and antifungal therapy directly to the skin and coat of your canine or feline companion, targeting the full spectrum of superficial dermatological infections that disrupt skin health, comfort, and coat quality. Combining the proven antimicrobial potency of Chlorhexidine Gluconate with the broad-spectrum antifungal activity of Ketoconazole in a pH-balanced, paraben-free, and alcohol-free base, Onfyte Shampoo is specifically designed to address infected wounds and cuts, eczema, dermatitis, pyoderma, ringworm, and idiopathic skin conditions that make your pet's daily life uncomfortable. What distinguishes Onfyte from standard medicated shampoos is its proprietary Unique Drug Depot Technology, which prolongs the retention of active ingredients at the skin surface after rinsing, extending antimicrobial contact time well beyond the bath and reinforcing the therapeutic benefit between applications. Dermatologically tested and formulated in India for the climatic and infectious challenges specific to the Indian subcontinent, Onfyte Multi-Infection Shampoo is a thoughtful, science-driven solution for pet parents managing skin infections in their beloved companions. Animeal is proud to offer Onfyte Multi-Infection Shampoo as part of its curated range of veterinary-grade topical dermatological solutions.
Ingredients:
Chlorhexidine Gluconate (Chlorhexidini Gluconas):Chlorhexidine gluconate is one of the most extensively studied and widely deployed topical antiseptics in both human and veterinary medicine, valued for its reliable broad-spectrum activity against gram-positive bacteria, gram-negative bacteria, and yeast species including Malassezia pachydermatis, the most common fungal pathogen of canine skin. Its mechanism of action is both multifaceted and highly effective: the chlorhexidine cation carries a strong positive charge that enables it to interact electrostatically with the negatively charged phospholipid groups in microbial cell walls and membranes. At bacteriostatic concentrations, this electrostatic binding disrupts cell membrane permeability, causing leakage of intracellular components. At bactericidal concentrations, chlorhexidine causes complete cytoplasmic membrane collapse and coagulation of intracellular proteins, resulting in rapid and irreversible microbial cell death. A defining and clinically critical property of chlorhexidine is its substantivity, meaning that even after rinsing, it binds to the stratum corneum of the skin and hair shaft surfaces and continues to exert antimicrobial activity for hours to days. This substantive residual effect is substantially enhanced by Onfyte's proprietary Unique Drug Depot Technology, creating a sustained drug reservoir at the skin surface that reinforces protection between shampoo sessions. Chlorhexidine is active against Staphylococcus pseudintermedius and Staphylococcus aureus, the gram-positive organisms most commonly implicated in canine pyoderma, as well as gram-negative pathogens including Pseudomonas and Escherichia species that can colonise moist, inflamed skin in dogs and cats.
Ketoconazole (Ketoconazolum):Ketoconazole is a synthetic imidazole antifungal agent with clinically established activity against a broad spectrum of dermatophytes, yeasts, and polymorphic fungi that colonise the skin surface and hair follicles of companion animals. Its antifungal mechanism is highly selective and operates at the level of fungal membrane biosynthesis. Ketoconazole inhibits the cytochrome P-450 enzyme lanosterol 14-alpha-demethylase, a fungal-specific enzyme that catalyses a critical step in the conversion of lanosterol to ergosterol, the principal structural sterol of the fungal cell membrane. By blocking ergosterol synthesis, ketoconazole causes the accumulation of toxic methylated sterol precursors within the fungal cell membrane, leading to disruption of membrane fluidity and integrity, increased permeability, leakage of intracellular contents, and ultimately fungal cell death. Ketoconazole's topical antifungal spectrum includes Malassezia pachydermatis responsible for yeast dermatitis and otitis, Microsporum canis and Trichophyton mentagrophytes responsible for ringworm (dermatophytosis), Candida species, and Aspergillus species. Clinical research confirms that ketoconazole demonstrates enhanced antifungal activity against dermatophytes and Malassezia when formulated in combination with chlorhexidine, as the two agents act synergistically on fungal cell architecture through complementary and mutually reinforcing mechanisms.
Unique Drug Depot Technology:Onfyte's proprietary Unique Drug Depot Technology is a formulation innovation that addresses one of the key limitations of conventional medicated shampoos: the fact that thorough rinsing reduces the duration of active ingredient contact with skin to only the wash period itself. The Drug Depot Technology creates a controlled-release depot of the active antimicrobial agents within the stratum corneum and hair follicle orifices, allowing Chlorhexidine Gluconate and Ketoconazole to continue diffusing into the cutaneous microenvironment for an extended period after rinsing. This prolonged post-rinse delivery substantially increases the cumulative antimicrobial exposure of skin pathogens between bathing sessions, supporting faster resolution of infection, greater reduction of microbial load with each application, and a more sustained protective barrier against recolonisation.
pH-Balanced, Paraben-Free, Alcohol-Free Base:The shampoo base is formulated to maintain a pH compatible with the canine and feline skin surface, typically slightly more acidic than human skin and distinct from the near-neutral pH of many human-formulated shampoos. A pH-balanced formulation prevents disruption of the skin's acid mantle, preserving the natural antimicrobial and moisture-retaining function of the epidermal barrier during and after treatment. The deliberate exclusion of parabens and alcohol addresses two common sources of skin sensitisation and barrier disruption in medicated pet shampoos, making Onfyte an appropriate choice for pets with already compromised, inflamed, or hypersensitive skin where additional chemical irritation would impede rather than support recovery.
Features and Benefits
Dual antibacterial and antifungal action in a s...
Dual antibacterial and antifungal action in a single application: Onfyte Multi-Infection Shampoo combines Chlorhexidine Gluconate and Ketoconazole to simultaneously target bacterial pyoderma, yeast overgrowth, dermatophytosis, and mixed skin infections that frequently co-occur in dogs and cats with compromised skin barriers. This dual-agent approach reduces the need for multiple separate topical products and simplifies the management of complex or multi-pathogen skin conditions.
Unique Drug Depot Technology extends active ingredient contact beyond the bath: Unlike conventional medicated shampoos whose antimicrobial benefit is largely limited to the duration of the wash, Onfyte's proprietary formulation technology creates a sustained-release reservoir of active agents within the stratum corneum, continuing to deliver Chlorhexidine Gluconate and Ketoconazole to the skin surface long after rinsing. This extended post-wash delivery maximises the therapeutic benefit of each application and reinforces the skin's antimicrobial defence between bathing sessions.
Effectively addresses a comprehensive range of superficial skin infections: Onfyte targets infected wounds and cuts, eczema, dermatitis, pyoderma, ringworm, and idiopathic skin conditions in a single multi-action formulation, making it a versatile go-to solution for Indian pet parents managing the diverse dermatological challenges that dogs and cats face in India's hot and humid conditions. The broad antimicrobial spectrum covers the most clinically relevant bacterial, yeast, and dermatophytic pathogens of companion animal skin.
pH-balanced base protects the skin's natural acid mantle during treatment: The formulation is calibrated to a pH appropriate for canine and feline skin, preserving the acid mantle that acts as the skin's first line of defence against environmental pathogens and moisture loss. Maintaining correct pH during medicated shampoo use is clinically important, as repeated exposure to pH-inappropriate products can worsen skin barrier dysfunction and prolong the infection cycle that the shampoo is intended to resolve.
Paraben-free and alcohol-free for safe use on sensitive and infected skin: The deliberate exclusion of parabens and alcohol from the formulation reduces the risk of additional chemical sensitisation, stinging, or barrier disruption in pets whose skin is already inflamed, excoriated, or compromised by infection. This makes Onfyte appropriate for use on pets with reactive skin types, ongoing dermatological conditions, and skin that may be painful or hypersensitive to harsher medicated bases.
Dermatologically tested and formulated in India for Indian conditions: Onfyte has been dermatologically tested for safety and efficacy, and is specifically formulated for the Indian climatic and infectious environment, where warm temperatures, high humidity, and year-round outdoor exposure create conditions highly conducive to bacterial and fungal skin infections in companion animals. This India-specific formulation context ensures that the product's antimicrobial profile and base characteristics are matched to the real-world challenges faced by Indian pet parents.
Usage and Applications
How to Use:Wet your pet's coat thoroughly w...
How to Use:
Wet your pet's coat thoroughly with lukewarm water before applying Onfyte Multi-Infection Shampoo, ensuring the water penetrates down to the skin surface and not just the outer coat. Apply a generous and appropriate amount of shampoo to the coat, distributing it evenly across the affected skin areas and surrounding regions. Massage the shampoo deeply into the coat using your fingertips, working it into a rich lather and ensuring it makes thorough contact with the skin surface rather than remaining on the outer hair shaft only. This deep contact is essential for the active ingredients and Drug Depot Technology to interact effectively with the cutaneous environment where pathogens reside. Allow the shampoo to remain in full contact with the skin for a minimum of 5 to 10 minutes before rinsing; this contact time is critical for both the immediate antimicrobial activity and the formation of the drug depot within the stratum corneum. Rinse thoroughly with clean water, ensuring that all shampoo residue is removed from the coat, as retained surfactant residue may cause skin irritation. Towel dry or allow your pet to air-dry in a warm, draught-free environment. Avoid contact with your pet's eyes, ear canals, nose, and mouth during application; if accidental contact occurs with the eyes, flush with clean water immediately. Do not allow your pet to lick the shampoo during the contact time period. Use as directed by your veterinarian for the specific skin condition being treated, and complete the recommended frequency and duration of the shampoo protocol even if clinical improvement is visible before completion. For external use only on dogs and cats.
Storage Advice:
Store unopened Onfyte Multi-Infection Shampoo in a cool, dry place below 25 degrees Celsius, away from direct sunlight and heat sources. Keep the cap firmly closed between uses to prevent contamination of the formulation and to preserve the stability of the active pharmaceutical ingredients and the Drug Depot Technology carrier system. Do not freeze. Once opened, use within the period indicated on the packaging. Do not use after the best-before date printed on the bottle. Keep out of the reach of children and away from food preparation surfaces. This product is for external use on animals only.
About the Brand:
Aranex is an Indian veterinary pharmaceutical company dedicated to providing those who raise and care for animals with high-quality products and services that address real therapeutic concerns in veterinary practice and companion animal health. Driven by a mission to improve the health of animals, people, and the planet simultaneously, Aranex operates with core values centred on visionary thinking, customer responsiveness, and a deep responsibility towards animals and society. The company focuses its expertise on developing veterinary medicines and dermatological solutions that address the specific infectious and environmental challenges faced by companion animals in India, leveraging pharmaceutical innovation such as the proprietary Drug Depot Technology to deliver extended therapeutic efficacy that goes beyond standard topical formulations. Aranex's commitment to quality-conscious, science-backed, and India-appropriate veterinary solutions aligns with Animeal's commitment to offering only the most trusted and genuinely effective topical care products for your beloved companions. Discover the full Aranex range today through Animeal.
Disclaimer:
Please note that while Onfyte Multi-Infection Shampoo is formulated from Chlorhexidine Gluconate and Ketoconazole in a pH-balanced, paraben-free, and alcohol-free base and is appropriate for topical use on dogs and cats with bacterial and fungal skin infections, it is a complementary medicated topical shampoo and is not a substitute for a veterinary diagnosis, laboratory culture and sensitivity testing, or a comprehensive dermatological treatment plan for severe, deep-seated, or recurrent skin infections. This product addresses superficial skin conditions and should not be used as the sole management strategy for conditions requiring systemic antibiotic or antifungal therapy. For pets with known hypersensitivity to chlorhexidine or ketoconazole, severe open wounds, conditions involving deeper tissue infection, or skin conditions that have not responded to topical management after an appropriate trial period, consult your veterinarian before continuing use. Animeal supports your pet's health and happiness journey but does not replace the advice of a qualified veterinary professional.
